Publikationen
Zeitschriftenartikel (43)
1.
Zeitschriftenartikel
15 (1), 1147 (2024)
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications 2.
Zeitschriftenartikel
15, 411 (2024)
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design. Nature Communications 3.
Zeitschriftenartikel
52, S. 391 - 411 (2023)
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy. Annual Review of Biophysics 4.
Zeitschriftenartikel
EIGER2 hybrid-photon-counting X-ray detectors for advanced synchrotron diffraction experiments. Journal of Synchrotron Radiation, S. 723 - 738 (2023)
5.
Zeitschriftenartikel
186 (23), e16, S. 5054 - 5067 (2023)
Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell 6.
Zeitschriftenartikel
50 (9), S. 5282 - 5298 (2022)
Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 7.
Zeitschriftenartikel
11, 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life 8.
Zeitschriftenartikel
11 (12), 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life 9.
Zeitschriftenartikel
587 (7832), S. 157 - 161 (2020)
Atomic-resolution protein structure determination by cryo-EM. Nature 10.
Zeitschriftenartikel
6 (30), eaba3916 (2020)
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 11.
Zeitschriftenartikel
180 (6), S. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 12.
Zeitschriftenartikel
27 (7), S. 1124 - 1136 (2019)
Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 13.
Zeitschriftenartikel
17 (7), S. 471 - 492 (2018)
Cryo-EM in drug discovery: Achievements, limitations and prospects. Nature Reviews Drug Discovery 14.
Zeitschriftenartikel
8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications 15.
Zeitschriftenartikel
353 (6306), S. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 16.
Zeitschriftenartikel
16 (12), S. 3103 - 3112 (2016)
The ribosome cooperates with the assembly chaperone pICln to initiate formation of snRNPs. Cell Reports 17.
Zeitschriftenartikel
353 (6299), S. 594 - 598 (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science 18.
Zeitschriftenartikel
65 (1), S. 23 - 34 (2016)
Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy. Microscopy 19.
Zeitschriftenartikel
12 (9), S. 859 - 865 (2015)
ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods 20.
Zeitschriftenartikel
34 (14), S. 1925 - 1941 (2015)
Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization. EMBO Journal 21.
Zeitschriftenartikel
21 (4), S. 613 - 614 (2015)
Assembly of RNPs: help needed. RNA 22.
Zeitschriftenartikel
26 (2), S. 161 - 171 (2015)
The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Molecular Biology of the Cell 23.
Zeitschriftenartikel
22 (6), S. 923 - 930 (2014)
Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit. Structure 24.
Zeitschriftenartikel
93 (3), S. 106 - 117 (2014)
Phosphoregulation of the human SMN complex. European Journal of Cell Biology 25.
Zeitschriftenartikel
49 (4), S. 692 - 703 (2013)
Structural basis of assembly chaperone- mediated snRNP formation. Molecular Cell 26.
Zeitschriftenartikel
2 (5), S. 718 - 731 (2011)
Biogenesis of spliceosomal small nuclear ribonucleoproteins. Wiley Interdisciplinary Reviews: RNA 27.
Zeitschriftenartikel
35 (12), S. 676 - 683 (2010)
Cellular strategies for the assembly of molecular machines. Trends in biochemical sciences 28.
Zeitschriftenartikel
16 (8), S. 1646 - 1659 (2010)
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA 29.
Zeitschriftenartikel
66 (6), S. 685 - 697 (2010)
A crystallization screen based on alternative polymeric precipitants. Acta Crystallographica Section D 30.
Zeitschriftenartikel
16 (4), S. 817 - 827 (2010)
LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication. RNA 31.
Zeitschriftenartikel
106 (32), S. 13517 - 13522 (2009)
Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates. Proceedings of the National Academy of Sciences of the USA 32.
Zeitschriftenartikel
21 (3), S. 387 - 393 (2009)
The role of RNP biogenesis in spinal muscular atrophy. Current Opinion in Cell Biology 33.
Zeitschriftenartikel
18 (7), S. 1288 - 1300 (2009)
IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1). Human Molecular Genetics 34.
Zeitschriftenartikel
15 (5), S. 484 - 487 (2009)
Molekulares Bodybuilding: Wie Zellen RNA-Proteinkomplexe herstellen. BioSpektrum 35.
Zeitschriftenartikel
135 (3), S. 497 - 509 (2008)
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Cell 36.
Zeitschriftenartikel
105 (29), S. 10045 - 10050 (2008)
Evolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the USA 37.
Zeitschriftenartikel
582 (14), S. 1997 - 2003 (2008)
Deciphering the assembly pathway of Sm‐class U snRNPs. FEBS Letters 38.
Zeitschriftenartikel
368 (2), S. 178 - 184 (2007)
A 5′-fluorosulfonylbenzoyladenosine-based method to identify physiological substrates of a Drosophila p21-activated kinase. Analytical Biochemistry 39.
Zeitschriftenartikel
282 (8), S. 5825 - 5833 (2007)
A comprehensive interaction map of the human survival of motor neuron (SMN) complex. Journal of Biological Chemistry 40.
Zeitschriftenartikel
13 (6), S. 610 - 613 (2007)
Wenn Muskeln die Nerven verlieren. Biospektrum 41.
Zeitschriftenartikel
12 (3), S. 113 - 121 (2006)
Spinal muscular atrophy: the RNP connection. Trends in Molecular Medicine 42.
Zeitschriftenartikel
14 (20), S. 3099 - 3111 (2005)
Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization. Human Molecular Genetics 43.
Zeitschriftenartikel
280 (41), S. 34435 - 34440 (2005)
Toward an assembly line for U7 snRNPs - Interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. Journal of Biological Chemistry Buchkapitel (1)
44.
Buchkapitel
Fatty Acid Synthase: Structure, Function, and Regulation. In: Macromolecular Protein Complexes IV: Structure and Function, S. 1 - 33 (Hg. Harris, R.; Marles-Wright, J.). Springer, Cham (2022)