Zeitschriftenartikel (279)

101.
Zeitschriftenartikel
Dhir, A.; Buratti, E.; van Santen, M. A.; Lührmann, R.; Baralle, F. E.: The intronic splicing code: Multiple factors involved in ATM pseudoexon definition. The EMBO Journal 29, S. 749 - 760 (2010)
102.
Zeitschriftenartikel
Schmidt, C.; Lenz, C.; Grote, M.; Lührmann, R.; Urlaub, H.: Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Analytical Chemistry 82 (7), S. 2784 - 2796 (2010)
103.
Zeitschriftenartikel
Weber, G.; Trowitzsch, S.; Kastner, B.; Lührmann, R.; Wahl, M. C.: Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO Journal 29, S. 4172 - 4184 (2010)
104.
Zeitschriftenartikel
Warkocki, Z.; Odenwälder, P.; Schmitzova, J.; Platzmann, F.; Stark, H.; Urlaub, H.; Ficner, R.; Fabrizio, P.; Lührmann, R.: Reconstitution of both steps of S. cerevisiae splicing with purified spliceosomal components. Nature Structural and Molecular Biology 16 (12), S. 1237 - 1243 (2009)
105.
Zeitschriftenartikel
Said, N.; Rieder, R.; Hurwitz, R.; Deckert, J.; Urlaub, H.; Vogel, J.: In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Research 37 (20), e133 (2009)
106.
Zeitschriftenartikel
Wirth, M.; Paap, F.; Fischle, W.; Wenzel, D.; Agafonov, D. E.; Samatov, T. R.; Wisniewski, J. R.; Jedrusik-Bode, M.: HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in Caenorhabditis elegans germ line. Molecular and Cellular Biology 29 (13), S. 3700 - 3709 (2009)
107.
Zeitschriftenartikel
Wolf, E.; Kastner, B.; Deckert, J.; Merz, C.; Stark, H.; Lührmann, R.: Exon, intron and splice site locations in the spliceosomal B complex. EMBO Journal 28, S. 2283 - 2292 (2009)
108.
Zeitschriftenartikel
Wahl, M. C.; Will, C. L.; Lührmann, R.: The spliceosome: design principles of a dynamic RNP machine. Cell 136 (4), S. 701 - 718 (2009)
109.
Zeitschriftenartikel
Fabrizio, P.; Dannenberg, J.; Dube, P.; Kastner, B.; Stark, H.; Urlaub, H.; Lührmann, R.: The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Molecular Cell 36 (4), S. 593 - 608 (2009)
110.
Zeitschriftenartikel
Trowitzsch, S.; Weber, G.; Lührmann, R.; Wahl, M. C.: Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. Journal of Molecular Biology 385 (2), S. 531 - 541 (2009)
111.
Zeitschriftenartikel
Eloranta, M. L.; Lövgren, T.; Finke, D.; Mathsson, L.; Rönnelid, J.; Kastner, B.; Alm, G.; Rönnblom, L.: Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells. Arthritis & Rheumatism 60, S. 2418 - 2427 (2009)
112.
Zeitschriftenartikel
Herold, N.; Will, C. L.; Wolf, E.; Kastner, B.; Urlaub, H.; Lührmann, R.: Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Molecular and Cellular Biology 29 (1), S. 281 - 301 (2009)
113.
Zeitschriftenartikel
Kofler, M.; Schuemann, M.; Merz, C.; Kosslick, D.; Schlundt, A.; Tannert, A.; Schaefer, M.; Lührmann, R.; Krause, E.; Freund, C.: Proline-rich sequence recognition I: Marking GYF and WW domain assembly sites in early spliceosomal complexes. Molecular and Cellular Proteomics 8, S. 2461 - 2473 (2009)
114.
Zeitschriftenartikel
Kuhn, A. N.; van Santen, M. A.; Schwienhorst, A.; Urlaub, H.; Lührmann, R.: Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 15 (1), S. 153 - 175 (2009)
115.
Zeitschriftenartikel
Lührmann, R.; Stark, H.: Structural mapping of spliceosomes by electron microscopy. Current Opinion in Structural Biology 19, S. 96 - 102 (2009)
116.
Zeitschriftenartikel
Pena, V.; Jovin, S. M.; Fabrizio, P.; Orlowski, J.; Bujnicki, J. M.; Lührmann, R.; Wahl, M. C.: Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Molecular Cell 35 (4), S. 454 - 466 (2009)
117.
Zeitschriftenartikel
Yu, Y.; Maroney, P. A.; Denker, J. A.; Zhang, X. H. F.; Dybkov, O.; Luehrmann, R.; Jankowsky, E.; Chasin, L. A.; Nilsen, T. W.: Dynamic regulation of alternative splicing by silencers that modulate 5´ splice site competition. Cell 135 (7), S. 1224 - 1236 (2008)
118.
Zeitschriftenartikel
Karaduman, R.; Dube, P.; Stark, H.; Fabrizio, P.; Kastner, B.; Luehrmann, R.: Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopy. RNA 14, S. 2528 - 2537 (2008)
119.
Zeitschriftenartikel
Trowitzsch, S.; Weber, G.; Luehrmann, R.; Wahl, M. C.: An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. The Journal of Biological Chemistry 283 (47), S. 32317 - 32327 (2008)
120.
Zeitschriftenartikel
Haecker, I.; Sander, B.; Golas, M. M.; Wolf, E.; Karagoez, E.; Kastner, B.; Stark, H.; Fabrizio, P.; Luehrmann, R.: Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nature Structural and Molecular Biology 15 (11), S. 1206 - 1212 (2008)
121.
Zeitschriftenartikel
Pena, V.; Rozov, A.; Fabrizio, P.; Luehrmann, R.; Wahl, M. C.: Structure and function of an RNase H domain at the heart of the spliceosome. The EMBO Journal 27 (21), S. 2929 - 2940 (2008)
122.
Zeitschriftenartikel
Licht, K.; Medenbach, J.; Luehrmann, R.; Kambach, C.; Bindereif, A.: 3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins. RNA 14 (8), S. 1532 - 1538 (2008)
123.
Zeitschriftenartikel
Pessa, H. K.; Will, C. L.; Meng, X.; Schneider, C.; Watkins, N. J.; Peraelae, N.; Nymark, M.; Turunen, J. J.; Luehrmann, R.; Frilander, M. J.: Minor spliceosome components are predominantly localized in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 105, S. 8655 - 8660 (2008)
124.
Zeitschriftenartikel
Bishop, T.; Gallagher, D.; Pascual, A.; Lygate, C. A.; de Bono, J. P.; Nicholls, L. G.; Ortega-Saenz, P.; Oster, H.; Wijeyekoon, B.; Sutherland, A. I. et al.; Grosfeld, A.; Aragones, J.; Schneider, M.; van Geyte, K.; Teixeira, D.; Diez-Juan, A.; Lopez-Barneo, J.; Channon, K. M.; Maxwell, P. H.; Pugh, C. W.; Davies, A. M.; Carmeliet, P.; Ratcliffe, P. J.: Abnormal sympathoadrenal development and systemic hypotension in PHD3–/– mice. Molecular and Cellular Biology 28 (10), S. 3386 - 3400 (2008)
125.
Zeitschriftenartikel
Mathew, R.; Hartmuth, K.; Moehlmann, S.; Urlaub, H.; Ficner, R.; Luehrmann, R.: Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nature Structural & Molecular Biology 15 (5), S. 435 - 443 (2008)
126.
Zeitschriftenartikel
Turunen, J. J.; Will, C. L.; Grote, M.; Luehrmann, R.; Frilander, M. J.: The U11-48K protein contacts the 5' splice site of U12-Type introns and the U11-59K protein. Molecular and Cellular Biology 28 (10), S. 3548 - 3560 (2008)
127.
Zeitschriftenartikel
Bessonov, S.; Anokhina, M.; Will, C. L.; Urlaub, H.; Luehrmann, R.: Isolation of an active step I spliceosome and composition of its RNP core. Nature 452 (7189), S. 846 - 850 (2008)
128.
Zeitschriftenartikel
Kastner, B.; Fischer, N.; Golas, M. M.; Sander, B.; Dube, P.; Boehringer, D.; Hartmuth, K.; Deckert, J.; Hauer, F.; Wolf, E. et al.; Uchtenhagen, H.; Urlaub, H.; Herzog, F.; Peters, J. M.; Porschke, D.; Luehrmann, R.; Stark, H.: GraFix: sample preparation for single-particle electron cryomicroscopy. Nature Methods 5 (1), S. 53 - 55 (2008)
129.
Zeitschriftenartikel
Rino, J.; Carvalho, T.; Braga, J.; Desterro, J. M.; Luehrmann, R.; Carmo-Fonseca, M.: A stochastic view of spliceosome assembly and recycling in the nucleus. PLoS Computational Biology 3 (10), e201, S. 2019 - 2031 (2007)
130.
Zeitschriftenartikel
Watkins, N. J.; Lemm, I.; Luehrmann, R.: Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis. Molecular and Cellular Biology 27 (20), S. 7018 - 7027 (2007)
131.
Zeitschriftenartikel
Kuehn-Hoelsken, E.; Dybkov, O.; Sander, B.; Luehrmann, R.; Urlaub, H.: Improved identification of enriched peptide–RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Research 35 (15), e95 (2007)
132.
Zeitschriftenartikel
Nielsen, T. K.; Liu, S.; Luehrmann, R.; Ficner, R.: Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). Journal of Molecular Biology 369 (4), S. 902 - 908 (2007)
133.
Zeitschriftenartikel
Liu, S.; Li, P.; Dybkov, O.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Carlomagno, T.; Wahl, M. C.: Binding of the human Prp31 nop domain to a composite RNA-protein platform in U4 snRNP. Science 316, 5821, S. 115 - 120 (2007)
134.
Zeitschriftenartikel
Behzadnia, N.; Golas, M. M.; Hartmuth, K.; Sander, B.; Kastner, B.; Deckert, J.; Dube, P.; Will, C. L.; Urlaub, H.; Stark, H. et al.; Luehrmann, R.: Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 26 (6), S. 1737 - 1748 (2007)
135.
Zeitschriftenartikel
Pena, V.; Liu, S.; Bujnicki, J. M.; Luehrmann, R.; Wahl, M. C.: Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa. Molecular Cell 25 (4), S. 615 - 624 (2007)
136.
Zeitschriftenartikel
Doenmez, G.; Hartmuth, K.; Kastner, B.; Will, C. L.; Luehrmann, R.: The 5′ end of U2 snRNA is in close proximity to U1 and functional sites of the Pre-mRNA in early spliceosomal complexes. Molecular Cell 25 (3), S. 399 - 411 (2007)
137.
Zeitschriftenartikel
Vazquez-Pianzola, P.; Hernandez, G.; Suter, B.; Rivera-Pomar, R.: Different modes of translation for hid, grim and sickle mRNAs in Drosophila. Cell Death and Differentiation 14 (2), S. 286 - 295 (2007)
138.
Zeitschriftenartikel
Merz, C.; Urlaub, H.; Will, C. L.; Luehrmann, R.: Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 13, S. 116 - 128 (2007)
139.
Zeitschriftenartikel
Sander, B.; Golas, M. M.; Makarov, E. M.; Brahms, H.; Kastner, B.; Luehrmann, R.; Stark, H.: Organization of Core Spliceosomal Components U5 snRNA Loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as Revealed by Electron Cryomicroscopy. Molecular Cell 24 (2), S. 267 - 278 (2006)
140.
Zeitschriftenartikel
Schultz, A.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.: RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoprotein. Journal of Biological Chemistry 281 (38), S. 28278 - 28286 (2006)
141.
Zeitschriftenartikel
Donnert, G.; Keller, J.; Medda, R.; Andrei, M. A.; Rizzoli, S. O.; Luehrmann, R.; Jahn, R.; Eggeling, C.; Hell, S. W.: Macromolecular-scale resolution in biological fluorescence microscopy. Proceedings of the National Academy of Sciences of the United States of America 103 (31), S. 11440 - 11445 (2006)
142.
Zeitschriftenartikel
Trippe, R.; Guschina, E.; Hossbach, M.; Urlaub, H.; Luehrmann, R.; Benecke, B. J.: Identification, cloning and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA 12 (8), S. 1494 - 1504 (2006)
143.
Zeitschriftenartikel
Deckert, J.; Hartmuth, K.; Boehringer, D.; Behzadnia, N.; Will, C. L.; Kastner, B.; Stark, H.; Urlaub, H.; Luehrmann, R.: Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and Cellular Biology 26 (14), S. 5528 - 5543 (2006)
144.
Zeitschriftenartikel
Lemm, I.; Girard, C.; Kuhn, A. N.; Watkins, N. J.; Schneider, M.; Bordonne, R.; Luehrmann, R.: Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Molecular Biology of the Cell 17, S. 3221 - 3231 (2006)
145.
Zeitschriftenartikel
Schultz, A.; Nottrott, S.; Watkins, N. J.; Luehrmann, R.: Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs. Molecular and Cellular Biology 26 (13), S. 5146 - 5154 (2006)
146.
Zeitschriftenartikel
Rhode, B.; Hartmuth, K.; Westhof, E.; Luehrmann, R.: Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes. EMBO Journal 25 (11), S. 2475 - 2486 (2006)
147.
Zeitschriftenartikel
Savarese, E.; Chae, O. W.; Trowitzsch, S.; Weber, G.; Kastner, B.; Akira, S.; Wagner, H.; Schmid, R. M.; Bauer, S.; Krug, A.: U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 107 (8), S. 3229 - 3234 (2006)
148.
Zeitschriftenartikel
Dybkov, O.; Will, C. L.; Deckert, J.; Behzadnia, N.; Hartmuth, K.; Luehrmann, R.: U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Molecular and Cellular Biology 26 (7), S. 2803 - 2816 (2006)
149.
Zeitschriftenartikel
Spadaccini, R.; Reidt, U.; Dybkov, O.; Will, C. L.; Frank, R.; Stier, G.; Corsini, L.; Wahl, M. C.; Luehrmann, R.; Sattler, M.: Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA 12 (3), S. 410 - 425 (2006)
150.
Zeitschriftenartikel
Behzadnia, N.; Hartmuth, K.; Will, C. L.; Luehrmann, R.: Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP. RNA 12, S. 1738 - 1746 (2006)
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