Publikationen

Hartmuth, K.; Urlaub, H.; Vornlocher, H. P.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proceedings of the National Academy of Sciences of the United States of America 99 (26), S. 16719 - 16724 (2002)

Granneman, S.; Pruijn, G. J. M.; Horstman, W.; van Venrooij, W. J.; Luehrmann, R.; Watkins, N. J.: The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in vitro. Journal of Biological Chemistry 277 (50), S. 48490 - 48500 (2002)

Makarov, E. M.; Makarova, O.; Urlaub, H.; Gentzel, M.; Will, C. L.; Wilm, M.; Luehrmann, R.: Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298 (5601), S. 2205 - 2208 (2002)

Ingelfinger, D.; Arndt-Jovin, D. J.; Luehrmann, R.; Achsel, T.: The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci. RNA-A Publication of the RNA Society 8 (12), S. 1489 - 1501 (2002)

Watkins, N. J.; Dickmanns, A.; Luehrmann, R.: Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP. Molecular and Cellular Biology 22 (23), S. 8342 - 8352 (2002)

De Antoni, A.; Schmitzova, J.; Trepte, H. H.; Gallwitz, D.; Albert, S.: Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. Journal of Biological Chemistry 277 (43), S. 41023 - 41031 (2002)

Nottrott, S.; Urlaub, H.; Luehrmann, R.: Hierarchical, clustered protein interact ions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO Journal 21 (20), S. 5527 - 5538 (2002)

Will, C. L.; Urlaub, H.; Achsel, T.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO Journal 21 (18), S. 4978 - 4988 (2002)

Martinez, J.; Patkaniowska, A.; Urlaub, H.; Luehrmann, R.; Tuschl, T.: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 (5), S. 563 - 574 (2002)

Bartels, C.; Klatt, C.; Luehrmann, R.; Fabrizio, P.: The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome. EMBO Reports 3 (9), S. 875 - 880 (2002)

Dellaire, G.; Makarov, E. M.; Cowger, J. J. M.; Longman, D.; Sutherland, H. G. E.; Luehrmann, R.; Torchia, J.; Bickmore, W. A.: Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes. Molecular and Cellular Biology 22 (14), S. 5141 - 5156 (2002)

Schneider, C.; Will, C. L.; Makarova, O.; Makarov, E. M.; Luehrmann, R.: Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Molecular and Cellular Biology 22 (10), S. 3219 - 3229 (2002)

Lagos-Quintana, M.; Rauhut, R.; Yalcin, A.; Meyer, J.; Lendeckel, W.; Tuschl, T.: Identification of tissue-specific microRNAs from mouse. Current Biology 12 (9), S. 735 - 739 (2002)

Makarova, O.; Makarov, E. M.; Liu, S.; Vornlocher, H. P.; Luehrmann, R.: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6 center dot U5 tri-snRNP formation and pre-mRNA splicing. EMBO Journal 21 (5), S. 1148 - 1157 (2002)

Huber, J.; Dickmanns, A.; Luehrmann, R.: The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro. Journal of Cell Biology 156 (3), S. 467 - 479 (2002)

Urlaub, H.; Hartmuth, K.; Luehrmann, R.: A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles. Methods 26 (2), S. 170 - 181 (2002)

Mougin, A.; Gottschalk, A.; Fabrizio, P.; Luehrmann, R.; Branlant, C.: Direct probing of RNA structure and RNA-protein interactions in purifies HeLa cells and yeast spliceosomal U4/U6.U5 tri-snRNP particles. Journal of Biological Chemistry 317 (5), S. 631 - 649 (2002)