Zeitschriftenartikel (282)
101.
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Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis. Nature Structural and Molecular Biology 17 (4), S. 403 - 409 (2010)
102.
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An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing. Molecular Cell 37 (6), S. 821 - 833 (2010)
103.
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Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nature Structural and Molecular Biology 17 (2), S. 216 - 222 (2010)
104.
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The intronic splicing code: Multiple factors involved in ATM pseudoexon definition. The EMBO Journal 29, S. 749 - 760 (2010)
105.
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Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Analytical Chemistry 82 (7), S. 2784 - 2796 (2010)
106.
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Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO Journal 29, S. 4172 - 4184 (2010)
107.
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Reconstitution of both steps of S. cerevisiae splicing with purified spliceosomal components. Nature Structural and Molecular Biology 16 (12), S. 1237 - 1243 (2009)
108.
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In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Research 37 (20), e133 (2009)
109.
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HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in Caenorhabditis elegans germ line. Molecular and Cellular Biology 29 (13), S. 3700 - 3709 (2009)
110.
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Exon, intron and splice site locations in the spliceosomal B complex. EMBO Journal 28, S. 2283 - 2292 (2009)
111.
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The spliceosome: design principles of a dynamic RNP machine. Cell 136 (4), S. 701 - 718 (2009)
112.
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The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Molecular Cell 36 (4), S. 593 - 608 (2009)
113.
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Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. Journal of Molecular Biology 385 (2), S. 531 - 541 (2009)
114.
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Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells. Arthritis & Rheumatism 60, S. 2418 - 2427 (2009)
115.
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Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Molecular and Cellular Biology 29 (1), S. 281 - 301 (2009)
116.
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Proline-rich sequence recognition I: Marking GYF and WW domain assembly sites in early spliceosomal complexes. Molecular and Cellular Proteomics 8, S. 2461 - 2473 (2009)
117.
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Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 15 (1), S. 153 - 175 (2009)
118.
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Structural mapping of spliceosomes by electron microscopy. Current Opinion in Structural Biology 19, S. 96 - 102 (2009)
119.
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Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Molecular Cell 35 (4), S. 454 - 466 (2009)
120.
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Dynamic regulation of alternative splicing by silencers that modulate 5´ splice site competition. Cell 135 (7), S. 1224 - 1236 (2008)
121.
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Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopy. RNA 14, S. 2528 - 2537 (2008)
122.
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An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. The Journal of Biological Chemistry 283 (47), S. 32317 - 32327 (2008)
123.
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Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nature Structural and Molecular Biology 15 (11), S. 1206 - 1212 (2008)
124.
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Structure and function of an RNase H domain at the heart of the spliceosome. The EMBO Journal 27 (21), S. 2929 - 2940 (2008)
125.
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3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins. RNA 14 (8), S. 1532 - 1538 (2008)
126.
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Minor spliceosome components are predominantly localized in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 105, S. 8655 - 8660 (2008)
127.
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Abnormal sympathoadrenal development and systemic hypotension in PHD3–/– mice. Molecular and Cellular Biology 28 (10), S. 3386 - 3400 (2008)
128.
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Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nature Structural & Molecular Biology 15 (5), S. 435 - 443 (2008)
129.
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The U11-48K protein contacts the 5' splice site of U12-Type introns and the U11-59K protein. Molecular and Cellular Biology 28 (10), S. 3548 - 3560 (2008)
130.
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Isolation of an active step I spliceosome and composition of its RNP core. Nature 452 (7189), S. 846 - 850 (2008)
131.
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GraFix: sample preparation for single-particle electron cryomicroscopy. Nature Methods 5 (1), S. 53 - 55 (2008)
132.
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A stochastic view of spliceosome assembly and recycling in the nucleus. PLoS Computational Biology 3 (10), e201, S. 2019 - 2031 (2007)
133.
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Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis. Molecular and Cellular Biology 27 (20), S. 7018 - 7027 (2007)
134.
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Improved identification of enriched peptide–RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Research 35 (15), e95 (2007)
135.
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Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). Journal of Molecular Biology 369 (4), S. 902 - 908 (2007)
136.
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Binding of the human Prp31 nop domain to a composite RNA-protein platform in U4 snRNP. Science 316, 5821, S. 115 - 120 (2007)
137.
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Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 26 (6), S. 1737 - 1748 (2007)
138.
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Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa. Molecular Cell 25 (4), S. 615 - 624 (2007)
139.
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The 5′ end of U2 snRNA is in close proximity to U1 and functional sites of the Pre-mRNA in early spliceosomal complexes. Molecular Cell 25 (3), S. 399 - 411 (2007)
140.
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Different modes of translation for hid, grim and sickle mRNAs in Drosophila. Cell Death and Differentiation 14 (2), S. 286 - 295 (2007)
141.
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Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 13, S. 116 - 128 (2007)
142.
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Organization of Core Spliceosomal Components U5 snRNA Loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as Revealed by Electron Cryomicroscopy. Molecular Cell 24 (2), S. 267 - 278 (2006)
143.
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RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoprotein. Journal of Biological Chemistry 281 (38), S. 28278 - 28286 (2006)
144.
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Macromolecular-scale resolution in biological fluorescence microscopy. Proceedings of the National Academy of Sciences of the United States of America 103 (31), S. 11440 - 11445 (2006)
145.
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Identification, cloning and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA 12 (8), S. 1494 - 1504 (2006)
146.
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Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and Cellular Biology 26 (14), S. 5528 - 5543 (2006)
147.
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Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Molecular Biology of the Cell 17, S. 3221 - 3231 (2006)
148.
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Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs. Molecular and Cellular Biology 26 (13), S. 5146 - 5154 (2006)
149.
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Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes. EMBO Journal 25 (11), S. 2475 - 2486 (2006)
150.
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U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 107 (8), S. 3229 - 3234 (2006)