Zeitschriftenartikel (242)
100.
Zeitschriftenartikel
Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation. Nature Communications 5, 5857 (2014)
101.
Zeitschriftenartikel
Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes. Journal of Biological Chemistry 289 (50), S. 34620 - 34626 (2014)
102.
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Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of Inorganic Biochemistry 141, S. 208 - 211 (2014)
103.
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A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 60 (4), S. 231 - 240 (2014)
104.
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Long-range correlated dynamics in intrinsically disordered proteins. Journal of the American Chemical Society 136 (46), S. 16201 - 16209 (2014)
105.
Zeitschriftenartikel
NMR-based detection of hydrogen/deuterium exchange in liposome-embedded membrane proteins. PLOS One 9 (11), e112374 (2014)
106.
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Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure 22 (10), S. 1501 - 1511 (2014)
107.
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Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 21 (10), S. 911 - 918 (2014)
108.
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α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease 70, S. 149 - 161 (2014)
109.
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Toward the functional oligomerization state of tryptophan-rich sensory proteins. Protein Science 23 (8), S. 1154 - 1160 (2014)
110.
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Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chemical Reviews 114 (13), S. 6632 - 6660 (2014)
111.
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Detection of a transient intramolecular hydrogen bond using (l)J(NH) scalar couplings. Journal of Magnetic Resonance 243, S. 93 - 97 (2014)
112.
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Nucleotide interactions of the human voltage-dependent anion channel. Journal of Biological Chemistry 289 (19), S. 13397 - 13406 (2014)
113.
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Site-specific copper-catalyzed oxidation of alpha-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease. Inorganic Chemistry 53 (9), S. 4350 - 4358 (2014)
114.
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Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1 beta. FEBS Letters 588 (7), S. 1094 - 1099 (2014)
115.
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Turn plasticity distinguishes different modes of amyloid-beta aggregation. Journal of the American Chemical Society 136 (13), S. 4913 - 4919 (2014)
116.
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Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 343 (6177), S. 1363 - 1366 (2014)
117.
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Hsp90-Tau complex reveals molecular basis for specificity in chaperone action. Cell 156 (5), S. 963 - 974 (2014)
118.
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Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 22 (2), S. 238 - 249 (2014)
119.
Zeitschriftenartikel
Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Experimental Dermatology 23 (1), S. 20 - 26 (2014)
120.
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Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2. Biochemistry 52 (50), S. 9068 - 9079 (2013)
121.
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Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 21 (12), S. 2162 - 2174 (2013)
122.
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Predicting the rotational tumbling of dynamic multidomain proteins and supramolecular complexes. Angewandte Chemie International Edition 52 (43), S. 11410 - 11414 (2013)
123.
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Beta-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology 74 (1), S. 109 - 118 (2013)
124.
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N-truncated amyloid beta (A beta) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathologica 126 (2), S. 189 - 205 (2013)
125.
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Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6), e1001577 (2013)
126.
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Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), S. 795 - 813 (2013)
127.
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Conserved amyloid core structure of stop mutants of the human prion protein. Prion 7 (3), S. 193 - 197 (2013)
128.
Zeitschriftenartikel
Structural plasticity in human heterochromatin protein 1 beta. PLoS One 8 (4), e60887 (2013)
129.
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Cold denaturation of a protein dimer monitored at atomic resolution. Nature Chemical Biology 9 (4), S. 264 - 270 (2013)
130.
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Imbalance of Hsp70 family variants fosters tau accumulation. FASEB Journal 27 (4), S. 1450 - 1459 (2013)
131.
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Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation. Angewandte Chemie-International Edition 52 (12), S. 3511 - 3515 (2013)
132.
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N-H spin-spin couplings: Probing hydrogen bonds in proteins. Angewandte Chemie-International Edition 52 (12), S. 3525 - 3528 (2013)
133.
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Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. Journal of Biological Chemistry 288 (5), S. 2994 - 3002 (2013)
134.
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Inhibition of tau filament formation by conformational modulation. Journal of the American Chemical Society 135 (7), S. 2853 - 2862 (2013)
135.
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Determination of amyloid core structure using chemical shifts. Protein Science 21 (12), S. 1948 - 1953 (2012)
136.
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Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. Journal of Biological Chemistry 287 (41), S. 34786 - 34800 (2012)
137.
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Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287 (40), S. 33756 - 33765 (2012)
138.
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Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: Leucine 46 hydrophobic pocket. PLoS One 7 (9), e0045024 (2012)
139.
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Beta-barrel mobility underlies closure of the voltage-dependent anion channel. Structure 20 (9), S. 1540 - 1549 (2012)
140.
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Cold-induced changes in the protein ubiquitin. PLoS One 7 (6), e37270 (2012)
141.
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Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. Journal of Biological Chemistry 287 (33), S. 27567 - 27579 (2012)
142.
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Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. ChemBioChem 13 (7), S. 930 - 950 (2012)
143.
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Aggregation of alpha Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathologica 123 (5), S. 671 - 683 (2012)
144.
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Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?—A critical assessment. Angewandte Chemie International Edition 51 (33), S. 8388 - 8391 (2012)
145.
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β-sheet core of Tau paired helical filaments revealed by solid-state NMR. Journal of the American Chemical Society 134 (34), S. 13982 - 13989 (2012)
146.
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Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. Journal of the American Chemical Society 134 (36), S. 15138 - 15148 (2012)
147.
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Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133 (40), S. 15842 - 15845 (2011)
148.
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Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly. Journal of Biological Chemistry 286 (37), S. 32036 - 32044 (2011)
149.
Zeitschriftenartikel
Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9), e24701 (2011)
150.
Zeitschriftenartikel
Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), S. 1202 - 1211 (2011)
151.
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The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), S. 2564 - 2578 (2011)
152.
Zeitschriftenartikel
Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), S. 49 - 60 (2011)
153.
Zeitschriftenartikel
Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), S. 2255 - 2265 (2011)
154.
Zeitschriftenartikel
Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5), e20289 (2011)
155.
Zeitschriftenartikel
Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), S. 387 - 395 (2011)
156.
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Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), S. 194 - 196 (2011)
157.
Zeitschriftenartikel
The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), S. 11520 - 11524 (2011)
158.
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Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), S. 111 - 119 (2011)
159.
Zeitschriftenartikel
Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), S. 22546 - 22551 (2010)
160.
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Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), S. 10668 - 10679 (2010)
161.
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The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences. Protein Science 19 (11), S. 2045 - 2054 (2010)
162.
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Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR. ChemBioChem 11 (13), S. 1829 - 1832 (2010)
163.
Zeitschriftenartikel
Automatic assignment of the intrinsically disordered protein Tau with 441-residues. Journal of the American Chemical Society 132 (34), S. 11906 - 11907 (2010)
164.
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Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. Journal of Biological Chemistry 285 (34), S. 26581 - 26598 (2010)
165.
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VDAC, a multi-functional mitochondrial protein regulating cell life and death. Molecular Aspects of Medicine 31 (3), S. 227 - 285 (2010)
166.
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Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry 285 (20), S. 14941 - 14954 (2010)
167.
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Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), S. 3184 - 3198 (2010)
168.
Zeitschriftenartikel
The native conformation of the human VDAC1 N terminus. Angewandte Chemie - International Edition 49 (10), S. 1882 - 1885 (2010)
169.
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Phosphorylation of synucleins by members of the polo-like kinase family. Journal of Biological Chemistry 285 (4), S. 2807 - 2822 (2010)
170.
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NMR characterization of long-range order in intrinsically disordered proteins. Journal of the American Chemical Society 132 (24), S. 8407 - 8418 (2010)
171.
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Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin. Journal of the American Chemical Society 132 (27), S. 9223 - 9225 (2010)
172.
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Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), S. 21057 - 21062 (2009)
173.
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Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), S. 17482 - 17489 (2009)
174.
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Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules. Biochemistry 48 (42), S. 10047 - 10055 (2009)
175.
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Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure 17 (9), S. 1169 - 1185 (2009)
176.
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A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry 48 (41), S. 9858 - 9870 (2009)
177.
Zeitschriftenartikel
Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), S. 1840 - 1846 (2009)
178.
Zeitschriftenartikel
Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), S. 3256 - 3268 (2009)
179.
Zeitschriftenartikel
Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)
180.
Zeitschriftenartikel
Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), S. 28 - 36 (2009)
181.
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Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), S. 35918 - 35928 (2008)
182.
Zeitschriftenartikel
Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), S. 2015 - 2019 (2008)
183.
Zeitschriftenartikel
Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), S. 10841 - 10851 (2008)
184.
Zeitschriftenartikel
Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), S. 15370 - 15375 (2008)
185.
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The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), S. 10740 - 10756 (2008)
186.
Zeitschriftenartikel
Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), S. 11801 - 11812 (2008)
187.
Zeitschriftenartikel
Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), S. 5046 - 5048 (2008)
188.
Zeitschriftenartikel
High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)
189.
Zeitschriftenartikel
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, S. 16895 - 16905 (2008)
190.
Zeitschriftenartikel
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), S. 512 - 523 (2008)
191.
Zeitschriftenartikel
NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), S. 679 - 690 (2008)
192.
Zeitschriftenartikel
The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), S. 1025 - 1034 (2008)
193.
Zeitschriftenartikel
High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), S. 1 - 13 (2008)
194.
Zeitschriftenartikel
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), S. 708 - 722 (2007)
195.
Zeitschriftenartikel
The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), S. 12230 - 12239 (2007)
196.
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Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), S. 3032 - 3033 (2007)
197.
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Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), S. 2574 - 2582 (2007)
198.
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The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), S. 5015 - 5025 (2007)