Publications | Max Planck Institute for Multidisciplinary Sciences

Max Planck Institute for Multidisciplinary Sciences

Journal Article (203)

151.

Journal Article

Zikich, D.; Mezer, A.; Varoqueaux, F.; Sheinin, A.; Junge, H. J.; Nachliel, E.; Melamed, R.; Brose, N.; Gutman, M.; Ashery, U.: Vesicle priming and recruitment by ubMunc13-2 are differentially regulated by calcium and calmodulin. Journal of Neuroscience 28 (8), pp. 1949 - 1960 (2008)

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152.

Journal Article

Brose, N.: For better or for worse: Complexins regulate SNARE function and vesicle fusion. Traffic 9, pp. 1403 - 1413 (2008)

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153.

Journal Article

Brose, N.: Altered complexin expression in psychiatric and neurological disorders: Cause or consequence ? Molecular Cells 25 (1), pp. 7 - 19 (2008)

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154.

Journal Article

Brose, N.: Kontaktscheue Neurone. Gehirn & Geist ( 7 ) (10), pp. 66 - 71 (2008)

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155.

Journal Article

Jamain, S.; Radyushkin, K.; Hammerschmidt, K.; Granon, S.; Boretius, S.; Varoqueaux, F.; Ramanantsoa, N.; Gallego, J.; Ronnenberg, A.; Winter, D. et al.; Frahm, J.; Fischer, J.; Bourgeron, T.; Ehrenreich, H.; Brose, N.: Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proceedings of the National Academy of Sciences of the United States of America 105 (5), pp. 1710 - 1715 (2008)

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156.

Journal Article

Speidel, D.; Salehi, A.; Obermueller, S.; Lundquist, I.; Brose, N.; Renström, E.; Rorsman, P.: CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic β cells. Cell Metabolism 7, pp. 57 - 67 (2008)

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157.

Journal Article

Jockusch, W. J.; Speidel, D.; Sigler, A.; Soerensen, J. B.; Varoqueaux, F.; Rhee, J.-S.; Brose, N.: CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell 131 (4), pp. 796 - 808 (2007)

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158.

Journal Article

Xue, M.; Reim, K.; Chen, X.; Chao, H.-T.; Deng, H.; Rizo, J.; Brose, N.; Rosenmund, C.: Distinct domains of complexin I differentially regulate neurotransmitter release. Nature Structural & Molecular Biology 14 (10), pp. 949 - 958 (2007)

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159.

Journal Article

Wegmeyer, H.; Egea, J.; Rabe, N.; Gezelius, H.; Filosa, A.; Enjin, A.; Varoqueaux, F.; Deininger, K.; Schnütgen, F.; Brose, N. et al.; Klein, R.; Kullander, K.; Betz, A.: EphA4-Dependent axon guidance is mediated by the RacGAP alpha 2-chimaerin. Neuron 55 (5), pp. 756 - 767 (2007)

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160.

Journal Article

Wojcik, S. M.; Brose, N.: Regulation of membrane fusion in synaptic excitation-secretion coupling: Speed and accuracy matter. Neuron 55 (1), pp. 11 - 24 (2007)

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161.

Journal Article

Glynn, D.; Reim, K.; Brose, N.; Morton, A. J.: Depletion of Complexin II does not affect disease progression in a mouse model of Huntington's disease (HD); support for role for complexin II in behavioural pathology in a mouse model of HD. Brain Research Bulletin 72 (2-3 Sp. Iss. Sp. Iss. SI), pp. 108 - 120 (2007)

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162.

Journal Article

Basu, J.; Betz, A.; Brose, N.; Rosenmund, C.: Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion. Journal of Neuroscience 27 (5), pp. 1200 - 1210 (2007)

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163.

Journal Article

Brose, N.: Autismus - wenn Nervenzellen kontaktscheu sind. BIOspektrum 13, pp. 614 - 616 (2007)

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164.

Journal Article

Chubykin, A. A.; Atasoy, D.; Etherton, M. R.; Brose, N.; Kavalali, E. T.; Gibson, J. R.; Südhof, T. C.: Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron 54, pp. 919 - 931 (2007)

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165.

Journal Article

Tordera, R. M.; Totterdell, S.; Wojcik, S. M.; Brose, N.; Elizalde, N.; Lasheras, B.; Del Rio, J.: Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1). European Journal of Neuroscience 25 (1), pp. 281 - 290 (2007)

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166.

Journal Article

Herzog, E.; Takamori, S.; Jahn, R.; Brose, N.; Wojcik, S. M.: Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus. Journal of Neurochemistry 99 (3), pp. 1011 - 1018 (2006)

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167.

Journal Article

Speidel, D.; Lundquist, I.; Brose, N.; Rorsman, P.; Renstrom, E.: Glucagon hypersecretion underlies glucose intolerance in CAPS-deficient mice. Diabetologia 49, pp. 354 - 355 (2006)

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168.

Journal Article

Varoqueaux, F.; Aramuni, G.; Rawson, R. L.; Mohrmann, R.; Missler, M.; Gottmann, K.; Zhang, W.; Südhof, T. C.; Brose, N.: Neuroligins determine synapse maturation and function. Neuron 51 (6), pp. 741 - 754 (2006)

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169.

Journal Article

Andrews-Zwilling, Y. S.; Kawabe, H.; Reim, K.; Varoqueaux, F.; Brose, N.: Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. Journal of Biological Chemistry 281 (28), pp. 19720 - 19731 (2006)

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170.

Journal Article

Kang, L. J.; He, Z.; Xu, P.; Fan, J.; Betz, A.; Brose, N.; Xu, T.: Munc13-1 is required for the sustained release of insulin from pancreatic β cells. Cell Metabolism 3 (6), pp. 463 - 468 (2006)

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171.

Journal Article

Kwan, E. P.; Xie, L.; Sheu, L.; Nolan, C. J.; Prentki, M.; Betz, A.; Brose, N.; Gaisano, H. Y.: Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes 55 (5), pp. 1421 - 1429 (2006)

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172.

Journal Article

Vinatier, J.; Herzog, E.; Plamont, M.-A.; Wojcik, S. M.; Schmidt, A.; Brose, N.; Daviet, L.; El Mestikawy, S.; Giros, B.: Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis. Journal of Neurochemistry 97 (4), pp. 1111 - 1125 (2006)

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173.

Journal Article

Wojcik, S. M.; Katsurabayashi, S.; Guillemin, I.; Friauf, E.; Rosenmund, C.; Brose, N.; Rhee, J.-S.: A shared vesicular carrier allows synaptic corelease of GABA and glycine. Neuron 50 (4), pp. 575 - 587 (2006)

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174.

Journal Article

Dimova, K.; Kawabe, H.; Betz, A.; Brose, N.; Jahn, O.: Characterization of the Munc13-calmodulin interaction by photoaffinity labeling. Biochimica et Biophysica Acta 1763, pp. 1256 - 1265 (2006)

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175.

Journal Article

Kalla, S.; Stern, M.; Basu, J.; Varoqueaux, F.; Reim, K.; Rosenmund, C.; Ziv, N. E.; Brose, N.: Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice. Journal of Neuroscience 26 (50), pp. 13054 - 13066 (2006)

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176.

Journal Article

Stevens, D. R.; Wu, Z.-X.; Matti, U.; Junge, H. J.; Schirra, C.; Becherer, U.; Wojcik, S. M.; Brose, N.; Rettig, J.: Identification of the minimal protein domain required for priming activity of Munc13-1. Current Biology 15 (24), pp. 2243 - 2248 (2005)

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177.

Journal Article

Gibson, H. E.; Reim, K.; Brose, N.; Morton, A. J.; Jones, S.: A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse. European Journal of Neuroscience 22 (7), pp. 1701 - 1712 (2005)

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178.

Journal Article

Glynn, D.; Drew, C. J.; Reim, K.; Brose, N.; Morton, A. J.: Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits. Human Molecular Genetics 14 (16), pp. 2369 - 2385 (2005)

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179.

Journal Article

Varoqueaux, F.; Sons, M. S.; Plomp, J. J.; Brose, N.: Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse. Molecular and Cellular Biology 25 (14), pp. 5973 - 5984 (2005)

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180.

Journal Article

Reim, K.; Wegmeyer, H.; Brandstätter, J. H.; Xue, M.; Rosenmund, C.; Dresbach, T.; Hofmann, K.; Brose, N.: Structurally and functionally unique complexins at retinal ribbon synapses. Journal of Cell Biology 169 (4), pp. 669 - 680 (2005)

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181.

Journal Article

Speidel, D.; Bruederle, C. E.; Enk, C.; Voets, T.; Varoqueaux, F.; Reim, K.; Becherer, U.; Fornal, F.; Ruggieri, S.; Holighaus, Y. et al.; Weihe, E.; Bruns, D.; Brose, N.; Rettig, J.: CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron 46 (1), pp. 75 - 88 (2005)

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182.

Journal Article

Neeft, M.; Wieffer, M.; de Jong, A. S.; Negroiu, G.; Metz, C. H. G.; van Loon, A.; Griffith, J.; Krijgsveld, J.; Wulffraat, N.; Koch, H. et al.; Heckt, A. J. R.; Brose, N.; Kleijmeer, M.; van der Sluijs, P.: Munc13-4 is an effector of Rab27a and controls secretion of lysosomes in hematopoietic cells. Molecular Biology of the Cell 16 (2), pp. 731 - 741 (2005)

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183.

Journal Article

Steinacker, P.; Schwarz, P.; Reim, K.; Brechlin, P.; Jahn, O.; Kratzin, H.; Aitken, A.; Wiltfang, J.; Aguzzi, A.; Bahn, E. et al.; Baxter, H. C.; Brose, N.; Otto, M.: Unchanged Survival Rates of 14-3-3γ Knockout Mice after Inoculation with Pathological Prion Protein. Molecular and Cellular Biology 25 (4), pp. 1339 - 1346 (2005)

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184.

Journal Article

Dresbach, T.; Neeb, A.; Meyer, G.; Gundelfinger, E. D.; Brose, N.: Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding. Molecular and Cellular Neuroscience 27 (3), pp. 227 - 235 (2004)

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185.

Journal Article

Meyer, G.; Varoqueaux, F.; Neeb, A.; Oschlies, M.; Brose, N.: The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Neuropharmacology 47 (5), pp. 724 - 733 (2004)

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186.

Journal Article

Varoqueaux, F.; Jamain, S.; Brose, N.: Neuroligin 2 is exclusively localized to inhibitory synapses. European Journal of Cell Biology 83 (9), pp. 449 - 456 (2004)

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187.

Journal Article

Junge, H. J.; Rhee, J. S.; Jahn, O.; Varoqueaux, F.; Spiess, J.; Waxham, M. N.; Rosenmund, C.; Brose, N.: Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity. Cell 118 (3), pp. 389 - 401 (2004)

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188.

Journal Article

Rossner, S.; Fuchsbrunner, K.; Lange-Dohna, C.; Hartlage-Rübsamen, M.; Bigl, V.; Betz, A.; Reim, K.; Brose, N.: Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing. The Journal of Biological Chemistry 279 (27), pp. 27841 - 27844 (2004)

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189.

Journal Article

Brose, N.; Betz, A.; Wegmeyer, H.: Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals. Current Opinion in Neurobiology 14 (3), pp. 328 - 340 (2004)

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190.

Journal Article

Wojcik, S. M.; Rhee, J. S.; Herzog, E.; Sigler, A.; Jahn, R.; Takamori, S.; Brose, N.; Rosenmund, C.: An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proceedings of the National Academy of Sciences of the United States of America 101 (18), pp. 7158 - 7163 (2004)

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191.

Journal Article

Nagy, G.; Reim, K.; Matti, U.; Brose, N.; Binz, T.; Rettig, J.; Neher, E.; Sørensen, J. B.: Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron 41 (3), pp. 417 - 429 (2004)

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192.

Journal Article

Speidel, D.; Varoqueaux, F.; Enk, C.; Nojiri, M.; Grishanin, R. N.; Martin, T. F.J.; Hofmann, K.; Brose, N.; Reim, K.: A family of Ca²⁺ -dependent activator proteins for secretion. The Journal of Biological Chemistry 278 (52), pp. 52802 - 52809 (2003)

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193.

Journal Article

Meyer, G.; Brose, N.: SPARring with spines. Science Magazine 302 (5649), pp. 1341 - 1344 (2003)

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194.

Journal Article

Sheu, L.; Pasyk, E. A.; Ji, J.; Huang, X.; Gao, X.; Varoqueaux, F.; Brose, N.; Gaisano, H. Y.: Regulation of insulin exocytosis by Munc13-1. The Journal of Biological Chemistry 278 (30), pp. 27556 - 27563 (2003)

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195.

Journal Article

Tobaben, S.; Varoqueaux, F.; Brose, N.; Stahl, B.; Meyer, G.: A brain specific isoform of small glutamine-rich tetratricopeptide repeat containing protein (SGT) binds to Hsc70 and the cysteine string protein. The Journal of Biological Chemistry 278 (40), pp. 38376 - 38383 (2003)

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196.

Journal Article

Sørensen, J. B.; Nagy, G.; Varoqueaux, F.; Nehring, R. B.; Brose, N.; Wilson, M. C.; Neher, E.: Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell 114, pp. 75 - 86 (2003)

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197.

Journal Article

Rosenmund, C.; Rettig, J.; Brose, N.: Molecular mechanisms of active zone function. Current Opinion in Neurobiology 13 (5), pp. 509 - 519 (2003)

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198.

Journal Article

Brose, N.; Neher, E.: Specificity emerges in the dissection of diacylglycerol- and protein kinase C-mediated signalling pathways. Proceedings of the National Academy of Sciences of the United States of America 99 (26), pp. 16522 - 16523 (2002)

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199.

Journal Article

Brose, N.; Rosenmund, C.: Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters. Journal of Cell Science 115 (23), pp. 4399 - 4411 (2002)

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200.

Journal Article

Varoqueaux, F.; Sigler, A.; Rhee, J. S.; Brose, N.; Enk, C.; Reim, K.; Rosenmund, C.: Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences of the United States of America 99 (13), pp. 9037 - 9042 (2002)

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