Publications of Tiago Fleming Outeiro

Outeiro, T. F.: Alpha-synuclein in Parkinson's disease: the debate that must go on. Parkinsonism & Related Disorders 136, 107850 (2025)

Ayoub, S.; Arabi, M.; Al-Najjar, Y.; Laswi, I.; Outeiro, T. F.; Chaari, A.: Glycation in Alzheimer’s Disease and Type 2 Diabetes: The Prospect of Dual Drug Approaches for Therapeutic Interventions. Molecular Neurobiology (2025)

Yuan, L.; Mao, L.-H.; Huang, Y.-Y.; Outeiro, T. F.; Li, W.; Vieira, T. C. R. G.; Li, J.-Y.: Stress granules: emerging players in neurodegenerative diseases. Translational Neurodegeneration 14, 22 (2025)

Lungu, R.; Fernandes, F. F.; Pires Monteiro, S.; Outeiro, T. F.; Shemesh, N.: Neural and vascular contributions to sensory impairments in a human alpha-synuclein transgenic mouse model of Parkinson’s disease. Journal of Cerebral Blood Flow and Metabolism (2025)

Ali, T. T.; Merghani, M.; Al-Azzani, M.; Gatzemeier, L. M.; Hoppert, M.; Kaloyanova, D.; Outeiro, T. F.; Neumann, P.; Popova, B.; Braus, G. H.: Rationally designed peptides inhibit the formation of α-synuclein fibrils and oligomers. European Journal of Medicinal Chemistry 289, 117452 (2025)

Amaral, L.; Martins, M.; Côrte-Real, M.; Outeiro, T. F.; Chaves, S. R.; Rego, A.: The neurotoxicity of pesticides: Implications for Parkinson's disease. Chemosphere 377, 144348 (2025)

Koss, D. J.; Todd, O.; Menon, H.; Anderson, Z.; Yang, T.; Findlay, L.; Graham, B.; Palmowski, P.; Porter, A.; Morrice, N. et al.; Walker, L.; Attems, J.; Ghanem, S. S.; El-Agnaf, O.; LeBeau, F. E.; Erskine, D.; Outeiro, T. F.: A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies. Molecular Neurodegeneration 20, 34 (2025)

Laurent, C.; Poncet, G.; Herskovits, T.; Alves de Sousa, R.; Le Corre, L.; Al-Azzani, M.; Koenig, A.; Birman, S.; Outeiro, T. F.; Mansuy, D. et al.; Dairou, J.: Inhibition of the Parkinson’s Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family. ACS Chemical Neuroscience 16 (6), pp. 1034 - 1042 (2025)

Flores-León, M.; Outeiro, T. F.: Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy. The FEBS Journal (2025)

Coles, N. P.; Elsheikh, S.; Quesnel, A.; Butler, L.; Jennings, C.; Tarzi, C.; Achadu, O. J.; Islam, M.; Kalesh, K.; Occhipinti, A. et al.; Angione, C.; Marles-Wright, J.; Koss, D. J.; Thomas, A. J.; Outeiro, T. F.; Filippou, P. S.; Khundakar, A. A.: Molecular Insights into α-Synuclein Fibrillation: A Raman Spectroscopy and Machine Learning Approach. ACS Chemical Neuroscience 16 (4), pp. 687 - 698 (2025)

Outeiro, T. F.; Höglinger, G.; Lang, A. E.; Vieira, T. C. R. G.: Protein misfolding: understanding biology to classify and treat synucleinopathies. Journal of Neural Transmission (2025)

Lang, A. E.; Höglinger, G. U.; Adler, C. H.; Berg, D.; Klein, C.; Outeiro, T. F.; Poewe, W.; Postuma, R.; Stoessl, A. J.: Initial biological classification of Lewy body diseases: No consensus on terminology. Alzheimer's & Dementia 21 (2), e14449 (2025)

da Silva, I. S.; Cardoso, A. R.; Reimer, L.; König, A.; van Riesen, C.; Outeiro, T. F.; Jensen, P. H.; Sales, M. G. F.: α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF. Biosensors and Bioelectronics 268, 116880 (2025)

Fonseca-Fonseca, L. A.; Fuentes, N. P.; Sánchez, J. R.; Iglesias, Á. T.; Outeiro, T. F.; Silva, V. D. A. d.; Costa, S. L.; Núñez-Figueredo, Y.: Correlational assessment of the effects of JM-20 in a rat model of parkinsonism. Behavioural Brain Research 476, 115269 (2025)

Coles, N. P.; Elsheikh, S.; Quesnel, A.; Butler, L.; Achadu, O.; Islam, M.; Kalesh, K.; Occhipinti, A.; Angione, C.; Marles-Wright, J. et al.; Koss, D. J.; Thomas, A. J.; Outeiro, T. F.; Filippou, P. S.; Khundakar, A. A.: Alpha-synuclein aggregation induces prominent cellular lipid changes as revealed by Raman spectroscopy and machine learning analysis. Brain Communications 7 (2), fcaf133 (2025)

Soares, E. S.; Queiroz, L. Y.; Gerhardt, E.; Prediger, R. D. S.; Outeiro, T. F.; Cimarosti, H. I.: SUMOylation modulates mitochondrial dynamics in an in vitro rotenone model of Parkinson's disease. Molecular and Cellular Neuroscience 131, 103969 (2024)

Amaro-Leal, Â.; Afonso, A. I.; Machado, F.; Shvachiy, L.; Rocha, I.; Outeiro, T. F.; Geraldes, V.: Dose-Dependent Cognitive Decline, Anxiety, and Locomotor Impairments Induced by Doxorubicin: Evidence from an Animal Model. Biology 13 (11), 939 (2024)

de Bruyn, E.; Dorn, A.E.; Rossetti, G.; Fernandez, C.; Outeiro, T. F.; Schulz, J.B.; Carloni, P.: Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution. Journal of Chemical Information and Modeling 64 (21), pp. 8215 - 8226 (2024)

Abdelrasol, H.; Chopra, A.; Shvachiy, L.; Beutner, D.; Outeiro, T. F.; Setz, C.: Stress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure. Cell Stress 8 (1), pp. 83 - 98 (2024)

Gatzemeier, L. M.; Meyer, F.; Outeiro, T. F.: Synthesis and Semi-Synthesis of Alpha-Synuclein: Insight into the Chemical Complexity of Synucleinopathies. Chembiochem 25 (20), e202400253 (2024)