Publications of S. Ort
All genres
Journal Article (10)
2015
Journal Article
26 (1), pp. 137 - 144 (2015)
Fluorogen activating protein–affibody probes: modular, no-wash measurement of epidermal growth factor receptors. Bioconjugate Chemistry 2011
Journal Article
50 (14), pp. 2870 - 2880 (2011)
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry 2010
Journal Article
49 (31), pp. 6784 - 6790 (2010)
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry 2009
Journal Article
48 (6), pp. 1256 - 1263 (2009)
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry 2008
Journal Article
378 (3), pp. 607 - 621 (2008)
Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology
Journal Article
582 (5), pp. 720 - 724 (2008)
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters 2007
Journal Article
367 (2), pp. 488 - 500 (2007)
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1. Journal of Molecular Biology 2006
Journal Article
45 (2), pp. 452 - 461 (2006)
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: Illuminating the role of main-chain reorganization. Biochemistry 2004
Journal Article
279 (32), pp. 33882 - 33889 (2004)
Substrate-induced conformational changes in human UMP/CMP kinase. Journal of Biological Chemistry 2003
Journal Article
10 (7), pp. 513 - 519 (2003)
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nature Structural Biology Conference Paper (3)
2008
Conference Paper
275 (Suppl. 1), p. 168 - 168 (2008)
Design and intracellular delivery of enzymes to enhance metabolic activation of prodrugs and improve anticancer therapy. FEBS Journal 2006
Conference Paper
273 (Suppl. 1), p. 50 - 50 (2006)
Engineering of nucleoside kinases to improve the activation of nucleoside analog prodrugs. FEBS Journal 2004
Conference Paper
13 (Suppl. 1), p. 190 - 190 (2004)
Substrate-induced conformational changes in human UMP/CMP kinase. Protein Science Thesis - PhD (1)
2005
Thesis - PhD
Proteindesign zur Verbesserung des Nukleosidanaloga-Umsatzes in menschlichen Zellen: Desoxycytidin-Kinase und UMP/CMP-Kinase. Dissertation, Universität Göttingen, Göttingen (2005)