Publications of M. Konrad
All genres
Journal Article (90)
2013
Journal Article
20 (4), pp. 533 - 540 (2013)
Free glycine accelerates the autoproteolytic activation of human asparaginase. Chemistry and Biology
Journal Article
13 (8), pp. 1472 - 1475 (2013)
Micro-optical lens array for fluorescence detection in droplet-based microfluidics. Lab on a Chip 2012
Journal Article
162 (3), pp. 599 - 605 (2012)
Controlled enzyme-catalyzed degradation of polymeric capsules templated on CaCO3: Influence of the number of LbL layers, conditions of degradation, and disassembly of multicompartments. Journal of Controlled Release
Journal Article
51 (34), pp. 6816 - 6826 (2012)
Structures of apo and product-bound human L-asparaginase: Insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry
Journal Article
279 (11), pp. 1915 - 1928 (2012)
Balance of human choline kinase isoforms is critical for cell cycle regulation: Implications for the development of choline kinase-targeted cancer therapy. FEBS Journal
Journal Article
7 (4), pp. 663 - 669 (2012)
Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line. ChemMedChem 2011
Journal Article
50 (14), pp. 2870 - 2880 (2011)
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry 2010
Journal Article
49 (44), pp. 8116 - 8120 (2010)
Enzyme reaction in the pores of CaCO3 particles upon ultrasound disruption of attached substrate-filled liposomes. Angewandte Chemie International Edition
Journal Article
122 (44), pp. 8293 - 8297 (2010)
Enzymreaktion in den Poren von CaCO3-Partikeln mit angelagerten, mit Substrat gefüllten Liposomen. Angewandte Chemie
Journal Article
5 (9), e12999 (2010)
Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms. PLoS ONE
Journal Article
53 (15), pp. 5792 - 5800 (2010)
The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): Implications for the development of dCK-activated acyclic guanine analogues. Journal of Medicinal Chemistry
Journal Article
49 (31), pp. 6784 - 6790 (2010)
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry 2009
Journal Article
48 (6), pp. 1256 - 1263 (2009)
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry 2008
Journal Article
17 (11), pp. 1946 - 1954 (2008)
Structural requirements for calmodulin binding to membrane-associated guanylate kinase homologs. Protein Science
Journal Article
89 (7), pp. 1672 - 1679 (2008)
Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells. Journal of General Virology
Journal Article
68 (6), pp. 1583 - 1594 (2008)
Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Molecular Microbiology
Journal Article
378 (3), pp. 607 - 621 (2008)
Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology
Journal Article
582 (5), pp. 720 - 724 (2008)
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters
Journal Article
283 (4), pp. 1902 - 1910 (2008)
Ultra short yeast tropomyosins show novel myosin regulation. Journal of Biological Chemistry
Journal Article
51 (14), pp. 4219 - 4225 (2008)
Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase. Journal of Medicinal Chemistry