Publications of R. Lührmann
All genres
Journal Article (189)
41.
Journal Article
21 (11), pp. 1993 - 2005 (2015)
Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 42.
Journal Article
125 (9), pp. 3572 - 3584 (2015)
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. Journal of Clinical Investigation 43.
Journal Article
162 (3), pp. 690 - 690.e1 (2015)
Snapshot: Spliceosome dynamics III. Cell 44.
Journal Article
162 (2), pp. 456 - 456.e1 (2015)
SnapShot: Spliceosome dynamics II. Cell 45.
Journal Article
4, e07320 (2015)
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife 46.
Journal Article
161 (6), pp. 1474 - 1474.e1 (2015)
SnapShot: Spliceosome dynamics I. Cell 47.
Journal Article
22 (2), pp. 138 - 144 (2015)
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 48.
Journal Article
29 (1), pp. 94 - 107 (2015)
The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development 49.
Journal Article
289 (50), pp. 34683 - 34698 (2014)
Identification of small molecule inhibitors of pre-mRNA splicing. The Journal of Biological Chemistry 50.
Journal Article
111 (44), pp. 15622 - 15629 (2014)
Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells. Proceedings of the National Academy of Sciences of the United States of America 51.
Journal Article
21 (10), pp. 911 - 918 (2014)
Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 52.
Journal Article
70 (6), pp. 1622 - 1630 (2014)
Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallographica D 53.
Journal Article
11 (4), pp. 298 - 312 (2014)
Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology 54.
Journal Article
20 (3), pp. 406 - 420 (2014)
Mass spectrometry–based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA 55.
Journal Article
21 (12), pp. 2162 - 2174 (2013)
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 56.
Journal Article
32 (21), pp. 2804 - 2818 (2013)
RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core. EMBO Journal 57.
Journal Article
8 (9), e74851 (2013)
The Prp19 complex directly functions in mitotic spindle assembly. PLoS One 58.
Journal Article
341 (6141), pp. 80 - 84 (2013)
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science 59.
Journal Article
19 (7), pp. 902 - 915 (2013)
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA 60.
Journal Article
27 (5), pp. 525 - 540 (2013)
Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes and Development