Publications of J. Liepe

Mishto, M.; Mansurkhodzhaev, A.; Ying, G.; Bitra, A.; Cordfunke, R. A.; Henze, S.; Paul, D.; Sidney, J.; Urlaub, H.; Neefjes, J. et al.; Sette, A.; Zajonc, D. M.; Liepe, J.: An in silico-in vitro pipeline identifying an HLA-A^*02:01⁺ KRAS G12V⁺ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 10, 2572 (2019)

Liepe, J.; Ovaa, H.; Mishto, M.: Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? Current Opinion in Immunology 52, pp. 81 - 86 (2018)

Dony, L.; Mackerodt, J.; Ward, S.; Filippi, S.; Stumpf, M. P. H.; Liepe, J.: PEITH(Θ) - perfecting experiments with information theory in python with GPU support. Bioinformatics 34 (7), pp. 1249 - 1250 (2018)

Mishto, M.; Liepe, J.: Post-translational peptide splicing and T cell responses. Trends in Immunology 38 (12), pp. 904 - 915 (2017)

Platteel, A. C. M.; Liepe, J.; van Eden, W.; Mishto, M.; Sijts, A. J. A. M.: An unexpected major role for proteasome-catalyzed peptide splicing in generation of T cell epitopes: Is there relevance for vaccine development? Frontiers in Immunology 8, 1441 (2017)

MacLean, A. L.; Smith, M. A.; Liepe, J.; Sim, A.; Khorshed, R.; Rashidi, N. M.; Scherf, N.; Kinner, A.; Roeder, I.; Lo Celso, C. et al.; Stumpf, M. P. H.: Single cell phenotyping reveals heterogeneity among haematopoietic stem cells following infection. Stem Cells 35 (11), pp. 2292 - 2304 (2017)

Platteel, A. C. M.; Liepe, J.; Textoris-Taube, K.; Keller, C.; Henklein, P.; Schalkwijk, H. H.; Cardoso, R.; Kloetzel, P. M.; Mishto, M.; Sijts, A. J. A. M.: Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8⁺ T cells during bacterial infection. Cell Reports 20 (5), pp. 1242 - 1253 (2017)

Dianzani, C.; Bellavista, E.; Liepe, J.; Verderio, C.; Martucci, M.; Santoro, A.; Chiocchetti, A.; Gigliotti, C. L.; Boggio, E.; Ferrara, B. et al.; Riganti, L.; Keller, C.; Janek, K.; Niewienda, A.; Fenoglio, C.; Sorosina, M.; Cantello, R.; Kloetzel, P. M.; Stumpf, M. P. H.; Paul, F.; Ruprecht, K.; Galimberti, D.; Boneschi, F. M.; Comi, C.; Dianzani, U.; Mishto, M.: Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis. Scientific Reports 7, 43718 (2017)

Liepe, J.; Marino, F.; Sidney, J.; Jeko, A.; Bunting, D. E.; Sette, A.; Kloetzel, P. M.; Stumpf, M.l. P. H.; Heck, A. J. R.; Mishto, M.: A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science 354 (6310), pp. 354 - 358 (2016)

Weavers, H.; Liepe, J.; Sim, A.; Wood, W.; Martin, P.-; Stumpf, M. P. H.: Systems analysis of the dynamic inflammatory response to tissue damage reveals spatiotemporal properties of the wound attractant gradient. Current Biology 26 (15), pp. 1975 - 1989 (2016)

Liepe, J.; Sim, A.; Weavers, H.; Ward, L.; Martin, P.; Stump, M. P. H.: Accurate reconstruction of cell and particle tracks from 3D live imaging data. Cell Systems 3 (1), pp. 102 - 107 (2016)

Platteel, A. C. M.; Mishto, M.; Textoris-Taube, K.; Keller, C.; Liepe, J.; Busch, D. H.; Kloetzel, P. M.; Sijts, A. J. A. M.: CD8(⁺) T cells of Listeria monocytogenes-infected mice recognize both linear and spliced proteasome products. European Journal of Immunology 46 (5), pp. 1109 - 1118 (2016)

Textoris-Taube, K.; Keller, C.; Liepe, J.; Henklein, P.; Sidney, J.; Sette, A.; Kloetzel, P. M.; Mishto, M.: The T210M substitution in the HLA-a*02:01 gp100 epitope strongly affects overall proteasomal cleavage site usage and antigen processing. Journal of Biological Chemistry 290 (51), pp. 30417 - 30428 (2015)

Jones, P. J. M.; Sim, A.; Taylor, H. B.; Bugeon, L.; Dallman, M. J.; Pereira, B.; Stumpf, M. P. H.; Liepe, J.: Inference of random walk models to describe leukocyte migration. Physical Biology 12 (6), 066001 (2015)

Liepe, J.; Holzhütter, H. G.; Bellavista, E.; Kloetzel, P. M.; Stumpf, M. P. H.; Mishto, M.: Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes. eLife 4, e07545 (2015)

Sim, A.; Liepe, J.; Stumpf, M. P.: Goldstein-Kac telegraph processes with random speeds: Path probabilities, likelihoods, and reported Lévy flights. Physical Review E 91 (4), 042115 (2015)

Mishto, M.; Liepe, J.; Textoris-Taube, K.; Keller, C.; Henklein, P.; Weberruss, M.; Dahlmann, B.; Enenkel, C.; Voigt, A.; Kuckelkorn, U. et al.; Stumpf, M. P. H.; Kloetzel, P. M.: Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation. European Journal of Immunology 44 (12), pp. 3508 - 3521 (2014)

McMahon, S. S.; Sim, A.; Filippi, S.; Johnson, R.; Liepe, J.; Smith, D.; Stumpf, M. P. H.: Information theory and signal transduction systems: From molecular information processing to network inference. Seminars in Cell and Developmental Biology 35, pp. 98 - 108 (2014)

Liepe, J.; Holzhütter, H. G.; Kloetzel, P. M.; Stumpf, M. P.; Mishto, M.: Modelling proteasome and proteasome regulator activities. Biomolecules 4 (2), pp. 585 - 599 (2014)

Liepe, J.; Kirk, P.; Filippi, S.; Toni, T.; Barnes, C. P.; Stumpf, M. P. H.: A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation. Nature Protocols 9, pp. 439 - 456 (2014)