Publications of T. Ruhwedel

Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A.; Tzvetanova, I.; Battefeld, A.; Kusch, K.; Kole, M. H. P.; Strenzke, N.; Möbius, W. et al.; de Hoz, L.; Nave, K.-A.: A role of oligodendrocytes in information processing. Nature Communications 11 (1), 5497 (2020)

Marshall-Phelps, K. L. H.; Kegel, L.; Baraban, M.; Ruhwedel, T.; Almeida, R. G.; Rubio-Brotons, M.; Klingseisen, A.; Benito-Kwiecinski, S. K.; Early, J. J.; Bin, J. M. et al.; Suminaite, D.; Livesey, M. R.; Möbius, W.; Poole, R. J.; Lyons, D. A.: Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b. Journal of Cell Biology 219 (7), e201909022 (2020)

Steyer, A. M.; Ruhwedel, T.; Nardis, C.; Werner, H. B.; Nave, K.-A.; Möbius, W.: Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy. Journal of Structural Biology 210 (2), 107492 (2020)

Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A.; Spieth, L.; Düking, T.; Schneider, L. V.; Schlaphoff, L.; Dreha-Kulaczewski, S.; Bley, A.; Burfeind, D. et al.; Kusch, K.; Mitkovski, M.; Ruhwedel, T.; Guder, P.; Röhse, H.; Denecke, J.; Gärtner, J.; Möbius, W.; Nave, K.-A.; Saher, G.: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica 138, pp. 147 - 161 (2019)

Steyer, A. M.; Ruhwedel, T.; Möbius, W.: Biological sample preparation by high-pressure freezing, microwave-assisted contrast enhancement, and minimal resin embedding for volume imaging. Journal of Visualized Experiments 145, e59156 (2019)

Fledrich, R.; Abdelaal, T. A. M.; Rasch, L.; Bansal, V.; Schütza, V.; Brügger, B.; Lüchtenborg, C.; Prukop, T.; Stenzel, J.; Rahman, R.U. et al.; Hermes, D.; Ewers, D.; Möbius, W.; Ruhwedel, T.; Katona, I.; Weis, J.; Klein, D.; Martini, R.; Brück, W.; Müller, W.C.; Bonn, S.; Bechmann, I.; Nave, K.-A.; Stassart, R. M.; Sereda, M. W.: Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy. Nature Communications 9, 3025 (2018)

Weil, M.-T.; Heibeck, S.; Töpperwien, M.; tom Dieck, S.; Ruhwedel, T.; Salditt, T.; Rodicio, M. C.; Morgan, J. R.; Nave, K.-A.; Möbius, W. et al.; Werner, H. B.: Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia. The Journal of Neuroscience 38 (29), pp. 6586 - 6596 (2018)

Cantuti-Castelvetri, L.; Fitzner, D.; Bosch-Queralt, M.; Weil, M.-T.; Su, M.; Sen, P.; Ruhwedel, T.; Mitkovski, M.; Trendelenburg, G.; Lütjohann, D. et al.; Möbius, W.; Simons, M.: Defective cholesterol clearance limits remyelination in the aged central nervous system. Science 359 (6376), pp. 684 - 688 (2018)

Berghoff, S. A.; Düking, T.; Spieth, L.; Winchenbach, J.; Stumpf, S. K.; Gerndt, N.; Kusch, K.; Ruhwedel, T.; Möbius, W.; Saher, G.: Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model. Acta Neuropathologica Communications 5, 94 (2017)

Berghoff, S. A.; Gerndt, N.; Winchenbach, J.; Stumpf, S. K.; Hosang, L.; Odoardi, F.; Ruhwedel, T.; Böhler, C.; Barrette, B.; Stassart, R. et al.; Liebetanz, D.; Dibaj, P.; Möbius, W.; Edgar, J. M.; Saher, G.: Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nature Communications 8, 14241 (2017)

Weil, M.-T.; Ruhwedel, T.; Möbius, W.; Simons, M.: Intracerebral injections and ultrastructural analysis of high-pressure frozen brain tissue. Current Protocols in Neuroscience 78, pp. 2.27.1 - 2.27.18 (2017)

Töpperwien, M.; Krenkel, M.; Ruhwedel, T.; Möbius, W.; Pacureanu, A.; Cloetens, P.; Salditt, T.: Phase-contrast tomography of sciatic nerves: image quality and experimental parameters. Journal of Physics: Conference Series 849, 012001 (2017)

Poggi, G.; Boretius, S.; Möbius, W.; Moschny, N.; Baudewig, J.; Ruhwedel, T.; Hassouna, I.; Wieser, G. L.; Werner, H. B.; Goebbels, S. et al.; Nave, K.-A.; Ehrenreich, H.: Cortical network dysfunction caused by a subtle defect of myelination. Glia 64 (11), pp. 2025 - 2040 (2016)

Weil, M.-T.; Möbius, W.; Winkler, A.; Ruhwedel, T.; Wrzos, C.; Romanelli, E.; Bennett, J. L.; Enz, L.; Goebels, N.; Nave, K.-A. et al.; Kerschensteiner, M.; Schaeren-Wiemers, N.; Stadelmann, C.; Simons, M.: Loss of myelin basic protein function triggers myelin breakdown in models of demyelinating diseases. Cell Reports 16 (2), pp. 314 - 322 (2016)

Schiller, S. A.; Seebode, C.; Wieser, G. L.; Goebbels, S.; Ruhwedel, T.; Horowitz, M.; Rapaport, D.; Sarig, O.; Sprecher, E.; Emmert, S.: Non-keratinocyte SNAP29 influences epidermal differentiation and hair follicle formation in mice. Experimental Dermatology: an International Journal for Rapid Publication of Short Reports in Experimental Dermatology 25, pp. 644 - 659 (2016)

Scheuer, T.; Brockmöller, V.; Blanco Knowlton, M.; Weitkamp, J.-H.; Ruhwedel, T.; Mueller, S.; Endesfelder, S.; Bührer, C.; Schmitz, T.: Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline. Glia 63 (10), pp. 1825 - 1839 (2015)

Gritsch, S.; Lu, J.; Thilemann, S.; Wörtge, S.; Möbius, W.; Bruttger, J.; Karram, K.; Ruhwedel, T.; Blanfeld, M.; Vardeh, D. et al.; Waisman, A.; Nave, K.-A.; Kuner, R.: Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice. Nature Communications 5, 5472 (2014)

Schertel, A.; Snaidero, N.; Han, H.-M.; Ruhwedel, T.; Laue, M.; Grabenbauer, M.; Möbius, W.: Cryo FIM-SEM: Volume imaging of cellular ultrastructure in native frozen specimens. Journal of Structural Biology 184, pp. 355 - 360 (2013)

Saher, G.; Rudolphi, F.; Corthals, K.; Ruhwedel, T.; Schmidt, K.-F.; Löwel, S.; Dibaj, P.; Barrette, B.; Möbius, W.; Nave, K.-A.: Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet. Nature Medicine 18 (7), pp. 1130 - 1135 (2012)

Goebbels, S.; Oltrogge, J.; Wolfer, S.; Wieser, G. L.; Nientiedt, T.; Pieper, A.; Ruhwedel, T.; Groszer, M.; Sereda, M. W.; Nave, K.-A.: Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy. Embo Molecular Medicine 4 (6), pp. 486 - 499 (2012)