Publications of Tiago Fleming Outeiro

Cullinane, P. W.; de Fernandez, E. P.; König, A.; Outeiro, T. F.; Jaunmuktane, Z.; Warner, T. T.: Type 2 Diabetes and Parkinson's Disease: A Focused Review of Current Concepts. Movement Disorders 38 (2), pp. 162 - 177 (2022)

Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M. et al.; Gollisch, T.; Outeiro, T. F.: Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, pp. 2397 - 2422 (2022)

Berkhoudt Lassen, L.; Schneider Thomsen, M.; Basso, E.; Füchtbauer, E.-M.; Füchtbauer, A.; Outeiro, T. F.; Jensen, P. H.; Moos, T.: Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation. Cells 11 (22), 3673 (2022)

Brás, I. C.; Khani, M. H.; Riedel, D.; Parfentev, I.; Gerhardt, E.; van Riesen, C.; Urlaub, H.; Gollisch, T.; Outeiro, T. F.: Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 269, 104721 (2022)

Magalhaes, R. S. S.; Boechat, F. C.; Brasil, A. A.; Neto, J. R. M.; Ribeiro, G. D.; Paranhos, L. H.; de Souza, N. N.; Vieira, T.; Outeiro, T. F.; Neves, B. C. et al.; Eleutherio, E. C. A.: Hexokinase 2: The preferential target of trehalose-6-phosphate over hexokinase 1. Journal of Cellular Biochemistry (2022)

Koss, D. J.; Erskine, D.; Porter, A.; Palmoski, P.; Menon, H.; Todd, O. G. J.; Leite, M.; Attems, J.; Outeiro, T. F.: Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies. Acta Neuropathologica Communications 10 (1), 98 (2022)

Domingues, R.; Sant'Anna, R.; Carvalho da Fonseca, A. C.; Robbs, B. K.; Foguel, D.; Outeiro, T. F.: Extracellular alpha-synuclein: Sensors, receptors, and responses. Neurobiology of Disease 168, 105696 (2022)

Thom, T.; Schmitz, M.; Fischer, A.-L.; Correia, A.; Correia, S.; Llorens, F.; Pique, A.-V.; Möbius, W.; Domingues, R.; Zafar, S. et al.; Stoops, E.; Silva, C. J.; Fischer, A.; Outeiro, T. F.; Zerr, I.: Cellular Prion Protein Mediates α-Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo. Movement Disorders 37 (1), pp. 39 - 51 (2022)

Oliveira, L. M. A.; Gasser, T.; Edwards, R.; Zweckstetter, M.; Melki, R.; Stefanis, L.; Lashuel, H. A.; Sulzer, D.; Vekrellis, K.; Halliday, G. M. et al.; Tomlinson, J. J.; Schlossmacher, M.; Jensen, P. H.; Schulze-Hentrich, J.; Riess, O.; Hirst, W.D.; El-Agnaf, O.; Mollenhauer, B.; Lansbury, P.; Outeiro, T. F.: Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)

Wong-Guerra, M.; Montano-Peguero, Y.; Ramírez-Sánchez, J.; Jiménez-Martin, J.; Fonseca-Fonseca, L. A.; Hernández-Enseñat, D.; Nonose, Y.; Valdés, O.; Mondelo-Rodriguez, A.; Ortiz-Miranda, Y. et al.; Bergado, G.; Carmenate, T.; Soto del Valle, R. M.; Pardo-Andreu, G.; Outeiro, T. F.; Padrón-Yaquis, A. S.; Martimbianco de Assis, A.; O Souza, D.; Nuñez-Figueredo, Y.: JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats. NeuroToxicology 87, pp. 70 - 85 (2021)

Masaracchia, C.; Koenig, A.; Valiente-Gabioud, A. A.; Peralta, P.; Favretto, F.; Strohäker, T.; Lazaro, D. F.; Zweckstetter, M.; Fernandez, C. O.; Outeiro, T. F.: Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2020)

Vaz, R.; Chapela, D.; Coelho, J.; Lopez, L.; Ferreira, J.; Alfonso, N.; Sousa, S.; Outeiro, T. F.: Tapentadol Prevent Motor Impairments in a Mouse Model of Dyskinesia. Neuroscience 404, pp. 58 - 71 (2020)

Brasil, A.D.; de Carvalho, M.D.C.; Gerhardt, E.; Queiroz, D.D.; Pereira, M.D.; Outeiro, T. F.; Eleutherio, E.C.A.: Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1. Proceedings of the National Academy of Sciences of the United States of America 116 (51), pp. 25991 - 2600 (2019)

Szegö, É. M.; Dominguez-Meijide, A.; Gerhardt, E.; König, A.; Koss, D. J.; Li, W.; Pinho, R.; Fahlbusch, C.; Johnson, M.; Santos, P. et al.; Villar-Piqué, A.; Thom, T.; Rizzoli, S.; Schmitz, M.; Li, J.; Zerr, I.; Attems, J.; Jahn, O.; Outeiro, T. F.: Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 28, pp. 65 - 77 (2019)

Rossetti, G.; Kless, A.; Lai, L.; Outeiro, T. F.; Carloni, P.: Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions 47, pp. 909 - 918 (2019)

Wu, J.; Ardah, M.; Haikal, C.; Svanbergsson, A.; Diepenbroek, M.; Vaikath, N. N.; Li, W.; Wang, Z.-Y.; Outeiro, T. F.; El-Agnaf, O. M. et al.; Li, J.-Y.: Dihydromyricetin and salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Translational neurodegeneration 8, 18 (2019)

Outeiro, T. F.; Harvey, K.; Dominguez-Meijide, A.; Gerhardt, E.: LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? Biochemical Society Transactions 47 (3), pp. 827 - 838 (2019)

Candelise, N.; Schmitz, M.; Llorens, F.; Villar-Piqué, A.; Cramm, M.; Thom, T.; da Silva Correia, S. M.; Gomes da Cunha, J. E.; Möbius, W.; Outeiro, T. F. et al.; González Álvarez, V.; Banchelli, M.; D'Andrea, C.; de Angelis, M.; Zafar, S.; Rabano, A.; Matteini, P.; Zerr, I.: Seeding variability of different alpha synuclein strains in synucleinopathies. Annals of Neurology 85 (5), pp. 691 - 703 (2019)

Vasili, E.; Dominguez-Meijide, A.; Outeiro, T. F.: Spreading of α-synuclein and tau: a systematic comparison of the mechanisms involved. Frontiers in Molecular Neuroscience 12, 107 (2019)

Carija, A.; Pinheiro, F.; Pujols, J.; Brás, I. C.; Fernandes Lázaro, D.; Santambrogio, C.; Grandori, R.; Outeiro, T. F.; Navarro, S.; Ventura, S.: Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity. Redox Biology 22, 101135 (2019)