Publikationen von S. Ort
Alle Typen
Zeitschriftenartikel (10)
Zeitschriftenartikel
26 (1), S. 137 - 144 (2015)
Fluorogen activating protein–affibody probes: modular, no-wash measurement of epidermal growth factor receptors. Bioconjugate Chemistry
Zeitschriftenartikel
50 (14), S. 2870 - 2880 (2011)
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry
Zeitschriftenartikel
49 (31), S. 6784 - 6790 (2010)
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry
Zeitschriftenartikel
48 (6), S. 1256 - 1263 (2009)
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry
Zeitschriftenartikel
378 (3), S. 607 - 621 (2008)
Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology
Zeitschriftenartikel
582 (5), S. 720 - 724 (2008)
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters
Zeitschriftenartikel
367 (2), S. 488 - 500 (2007)
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1. Journal of Molecular Biology
Zeitschriftenartikel
45 (2), S. 452 - 461 (2006)
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: Illuminating the role of main-chain reorganization. Biochemistry
Zeitschriftenartikel
279 (32), S. 33882 - 33889 (2004)
Substrate-induced conformational changes in human UMP/CMP kinase. Journal of Biological Chemistry
Zeitschriftenartikel
10 (7), S. 513 - 519 (2003)
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nature Structural Biology Konferenzbeitrag (3)
Konferenzbeitrag
275 (Suppl. 1), S. 168 - 168 (2008)
Design and intracellular delivery of enzymes to enhance metabolic activation of prodrugs and improve anticancer therapy. FEBS Journal
Konferenzbeitrag
273 (Suppl. 1), S. 50 - 50 (2006)
Engineering of nucleoside kinases to improve the activation of nucleoside analog prodrugs. FEBS Journal
Konferenzbeitrag
13 (Suppl. 1), S. 190 - 190 (2004)
Substrate-induced conformational changes in human UMP/CMP kinase. Protein Science Hochschulschrift - Doktorarbeit (1)
Hochschulschrift - Doktorarbeit
Proteindesign zur Verbesserung des Nukleosidanaloga-Umsatzes in menschlichen Zellen: Desoxycytidin-Kinase und UMP/CMP-Kinase. Dissertation, Universität Göttingen, Göttingen (2005)