Publikationen von M. Konrad
Alle Typen
Zeitschriftenartikel (90)
Zeitschriftenartikel
20 (4), S. 533 - 540 (2013)
Free glycine accelerates the autoproteolytic activation of human asparaginase. Chemistry and Biology
Zeitschriftenartikel
13 (8), S. 1472 - 1475 (2013)
Micro-optical lens array for fluorescence detection in droplet-based microfluidics. Lab on a Chip
Zeitschriftenartikel
162 (3), S. 599 - 605 (2012)
Controlled enzyme-catalyzed degradation of polymeric capsules templated on CaCO3: Influence of the number of LbL layers, conditions of degradation, and disassembly of multicompartments. Journal of Controlled Release
Zeitschriftenartikel
51 (34), S. 6816 - 6826 (2012)
Structures of apo and product-bound human L-asparaginase: Insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry
Zeitschriftenartikel
279 (11), S. 1915 - 1928 (2012)
Balance of human choline kinase isoforms is critical for cell cycle regulation: Implications for the development of choline kinase-targeted cancer therapy. FEBS Journal
Zeitschriftenartikel
7 (4), S. 663 - 669 (2012)
Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line. ChemMedChem
Zeitschriftenartikel
50 (14), S. 2870 - 2880 (2011)
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry
Zeitschriftenartikel
49 (44), S. 8116 - 8120 (2010)
Enzyme reaction in the pores of CaCO3 particles upon ultrasound disruption of attached substrate-filled liposomes. Angewandte Chemie International Edition
Zeitschriftenartikel
122 (44), S. 8293 - 8297 (2010)
Enzymreaktion in den Poren von CaCO3-Partikeln mit angelagerten, mit Substrat gefüllten Liposomen. Angewandte Chemie
Zeitschriftenartikel
5 (9), e12999 (2010)
Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms. PLoS ONE
Zeitschriftenartikel
53 (15), S. 5792 - 5800 (2010)
The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): Implications for the development of dCK-activated acyclic guanine analogues. Journal of Medicinal Chemistry
Zeitschriftenartikel
49 (31), S. 6784 - 6790 (2010)
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry
Zeitschriftenartikel
48 (6), S. 1256 - 1263 (2009)
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry
Zeitschriftenartikel
17 (11), S. 1946 - 1954 (2008)
Structural requirements for calmodulin binding to membrane-associated guanylate kinase homologs. Protein Science
Zeitschriftenartikel
89 (7), S. 1672 - 1679 (2008)
Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells. Journal of General Virology
Zeitschriftenartikel
68 (6), S. 1583 - 1594 (2008)
Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Molecular Microbiology
Zeitschriftenartikel
378 (3), S. 607 - 621 (2008)
Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology
Zeitschriftenartikel
582 (5), S. 720 - 724 (2008)
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters
Zeitschriftenartikel
283 (4), S. 1902 - 1910 (2008)
Ultra short yeast tropomyosins show novel myosin regulation. Journal of Biological Chemistry
Zeitschriftenartikel
51 (14), S. 4219 - 4225 (2008)
Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase. Journal of Medicinal Chemistry