Publications of R. Luehrmann

Hochleitner, E. O.; Kastner, B.; Froehlich, T.; Schmidt, A.; Luehrmann, R.; Arnold, G.; Lottspeich, F.: Protein stoichiometry of a multiprotein complex, the human spliceosomal U1 small nuclear ribonucleoprotein - Absolute quantification using isotope-coded tags and mass spectrometry. Journal of Biological Chemistry 280 (4), pp. 2536 - 2542 (2005)

Watkins, N. J.; Lemm, I.; Ingelfinger, D.; Schneider, C.; Hossbach, M.; Urlaub, H.; Luehrmann, R.: Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Molecular Cell 16 (5), pp. 789 - 798 (2004)

Doenmez, G.; Hartmuth, K.; Luehrmann, R.: Modified nucleotides at the 5 ' end of human U2 snRNA are required for spliceosomal E-complex formation. RNA 10 (12), pp. 1925 - 1933 (2004)

Narayanan, U.; Achsel, T.; Luehrmann, R.; Matera, A. G.: Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein. Molecular Cell 16 (2), pp. 223 - 234 (2004)

Granneman, S.; Vogelzangs, J.; Luehrmann, R.; van Venrooij, W. J.; Pruijn, G. J. M.; Watkins, N. J.: Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP. Molecular and Cellular Biology 24 (19), pp. 8600 - 8610 (2004)

Medenbach, J.; Schreiner, S.; Liu, S.; Luehrmann, R.; Bindereif, A.: Human U4/U6 snRNP recycling factor p110: Mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling. Molecular and Cellular Biology 24 (17), pp. 7392 - 7401 (2004)

Schaffert, N.; Hossbach, M.; Heintzmann, R.; Achsel, T.; Luehrmann, R.: RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies. EMBO Journal 23, pp. 3000 - 3009 (2004)

Schneider, C.; Will, C. L.; Brosius, J.; Frilander, M. J.; Luehrmann, R.: Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 101 (26), pp. 9584 - 9589 (2004)

Makarova, O.; Makarov, E. M.; Urlaub, H.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO Journal 23 (12), pp. 2381 - 2391 (2004)

Will, C. L.; Schneider, C.; Hossbach, M.; Urlaub, H.; Rauhut, R.; Elbashir, S. M.; Tuschl, T.; Luehrmann, R.: The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 10 (6), pp. 929 - 941 (2004)

Boehringer, D.; Makarov, E. M.; Sander, B.; Makarova, O.; Kastner, B.; Luehrmann, R.; Stark, H.: Three-dimensional structure of a pre-catalytic human spliceosomal complex B. Nature Structural and Molecular Biology 11 (5), pp. 463 - 468 (2004)

Pillai, R. S.; Grimmler, M.; Meister, G.; Will, C. L.; Luehrmann, R.; Fischer, U.; Schuemperli, D.: Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes & Development 17 (18), pp. 2321 - 2333 (2003)

Ingelfinger, D.; Gothel, S. F.; Marahiel, M. A.; Reidt, U.; Ficner, R.; Luehrmann, R.; Achsel, T.: Two protein-protein interaction sites on the spliceosome-associated human cyclophilin CypH. Nucleic Acids Research 31 (16), pp. 4791 - 4796 (2003)

Bartels, C.; Urlaub, H.; Luehrmann, R.; Fabrizio, P.: Mutagenesis suggests several roles of Snu114p in pre- mRNA splicing. Journal of Biological Chemistry 278 (30), pp. 28324 - 28334 (2003)

Reidt, U.; Wahl, M. C.; Fasshauer, D.; Horowitz, D.; Luehrmann, R.; Ficner, R.: Crystal Structure of a Complex Between Human Spliceosomal Cyclophilin H and a U4/U6 snRNP-60K Peptide. Journal of Molecular Biology 331, pp. 45 - 56 (2003)

Hartmuth, K.; Urlaub, H.; Vornlocher, H. P.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proceedings of the National Academy of Sciences of the United States of America 99 (26), pp. 16719 - 16724 (2002)

Granneman, S.; Pruijn, G. J. M.; Horstman, W.; van Venrooij, W. J.; Luehrmann, R.; Watkins, N. J.: The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in vitro. Journal of Biological Chemistry 277 (50), pp. 48490 - 48500 (2002)

Makarov, E. M.; Makarova, O.; Urlaub, H.; Gentzel, M.; Will, C. L.; Wilm, M.; Luehrmann, R.: Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298 (5601), pp. 2205 - 2208 (2002)

Ingelfinger, D.; Arndt-Jovin, D. J.; Luehrmann, R.; Achsel, T.: The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci. RNA-A Publication of the RNA Society 8 (12), pp. 1489 - 1501 (2002)

Will, C. L.; Urlaub, H.; Achsel, T.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO Journal 21 (18), pp. 4978 - 4988 (2002)