Max Planck Institute for Multidisciplinary Sciences

Publications

Journal Article (49)

1.

Journal Article

Dzyubenko, E.; Willig, K. I.; Yin, D.; Sardari, M.; Tokmak, E.; Labus, P.; Schmermund, B.; Hermann, D. M.: Structural changes in perineuronal nets and their perforating GABAergic synapses precede motor coordination recovery post stroke. Journal of Biomedical Science 30, 76 (2023)

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2.

Journal Article

Ray, A.; Christian, J. A.; Mosso, M. B.; Park, E.; Wegner, W.; Willig, K. I.; Barth, A. L.: Quantitative Fluorescence Analysis Reveals Dendrite-Specific Thalamocortical Plasticity in L5 Pyramidal Neurons during Learning. The Journal of Neuroscience 43 (4), pp. 584 - 600 (2023)

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Fuhrmann, M.; Gockel, N.; Arizono, M.; Dembitskaya, Y.; Naegerl, U. V.; Pennacchietti, F.; Damenti, M.; Testa, I.; Willig, K. I.: Super-Resolution Microscopy Opens New Doors to Life at the Nanoscale. The Journal of Neuroscience 42 (45), pp. 8488 - 8497 (2022)

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4.

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Grimm, E.; van der Hoeven, F.; Sardella, D.; Willig, K. I.; Engel, U.; Veits, N.; Engel, R.; Cavalcanti-Adam, E. A.; Bestvater, F.; Bordoni, L. et al.; Jennemann, R.; Schönig, K.; Schiessl, I. M.; Sandhoff, R.: A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis. PLoS One 17 (9), e0273660 (2022)

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5.

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Willig, K. I.: In vivo super-resolution of the brain - How to visualize the hidden nanoplasticity? iScience 25 (9), 104961 (2022)

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6.

Journal Article

Wegner, W.; Steffens, H.; Gregor, C.; Wolf, F.; Willig, K. I.: Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy. eLife 11, e73603 (2022)

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7.

Journal Article

Spieth, L.; Berghoff, S. A.; Stumpf, S. K.; Winchenbach, J.; Michaelis, T.; Watanabe, T.; Gerndt, N.; Düking, T.; Hofer, S.; Ruhwedel, T. et al.; Shaib, A. H.; Willig, K. I.; Kronenberg, K.; Karst, U.; Frahm, J.; Rhee, J. S.; Minguet, S.; Möbius, W.; Kruse, N.; von der Brelie, C.; Michels, P.; Stadelmann, C.; Hülper, P.; Saher, G.: Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neuro-Oncology Advances 3 (1), vdab140 (2021)

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8.

Journal Article

Kuljis, D. A.; Micheva, K. D.; Ray, A.; Wegner, W.; Bowman, R.; Madison, D. V.; Willig, K. I.; Barth, A. L.: Gephyrin-lacking PV synapses on neocortical pyramidal neurons. International Journal of Molecular Sciences 22 (18), 10032 (2021)

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9.

Journal Article

Ambrozkiewicz, M.; Borisova, E.; Schwark, M.; Ripamonti, S.; Schaub, T.; Smorodchenko, A.; Weber, A. I.; Rhee, H. J.; Altas, B.; Yilmaz, R. et al.; Mueller, S.; Piepkorn, L.; Horan, S. T.; Straussberg, R.; Zaqout, S.; Jahn, O.; Dere, E.; Rosário, M.; Boehm-Sturm, P.; Borck, G.; Willig, K. I.; Rhee, J. S.; Tarabykin, V.; Kawabe, H.: The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Molecular Psychiatry 26, pp. 1980 - 1995 (2021)

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10.

Journal Article

Steffens, H.; Wegner, W.; Willig, K. I.: In vivo STED microscopy: a roadmap to nanoscale imaging in the living mouse. Methods, 10.1016/j.ymeth.2019.05.020 (2019)

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11.

Journal Article

Neef, J.; Urban, N. T.; Ohn, T. L.; Frank, T.; Jean, P.; Hell, S. W.; Willig, K. I.; Moser, T.: Quantitative optical nanophysiology of Ca²⁺ signaling at inner hair cell active zones. Nature Communications 9, 290 (2018)

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supplementary-material

12.

Journal Article

Wegner, W.; Mott, A. C.; Grant, S. G. N.; Steffens, H.; Willig, K. I.: In vivo STED microscopy visualizes PSD95 sub-structures and morphological changes over several hours in the mouse visual cortex. Scientific Reports 8, 219 (2018)

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13.

Journal Article

Richardson, D. S.; Gregor, C.; Winter, F.; Urban, N. T.; Sahl, S. J.; Willig, K. I.; Hell, S. W.: SRpHi ratiometric pH biosensors for super-resolution microscopy. Nature Communications 8, 577 (2017)

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14.

Journal Article

Wegner, W.; Ilgen, P.; Gregor, C.; Van Dort, J.; Mott, A. C.; Steffens, H.; Willig, K. I.: In vivo mouse and live cell STED microscopy of neuronal actin plasticity using far-red emitting fluorescent proteins. Scientific Reports 7, 11781 (2017)

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15.

Journal Article

Hell, S. W.; Sahl, S. J.; Bates, M.; Zhuang, X.; Heintzmann, R.; Booth, M. J.; Bewersdorf, J.; Shtengel, G.; Hess, H.; Tinnefeld, P. et al.; Honigmann, A.; Jakobs, S.; Testa, I.; Cognet, L.; Lounis, B.; Ewers, H.; Davis, S. J.; Eggeling, C.; Klenerman, D.; Willig, K. I.; Vicidomini, G.; Castello, M.; Diaspro, A.; Cordes, T.: The 2015 super-resolution microscopy roadmap. Journal of Physics D: Applied Physics 48 (44), 443001 (2015)

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16.

Journal Article

Eggeling, C.; Willig, K. I.; Sahl, S. J.; Hell, S. W.: Lens-based fluorescence nanoscopy. Quarterly Reviews of Biophysics 48 (2), pp. 178 - 243 (2015)

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17.

Journal Article

Belov, V. N.; Mitronova, G.; Bossi, M. L.; Boyarski, V. P.; Hebisch, E.; Geisler, C.; Kolmakov, K.; Wurm, C. A.; Willig, K. I.; Hell, S. W.: Masked rhodamine dyes of five principal colors revealed by photolysis of a 2-diazo-1-indanone caging group: synthesis, photophysics, and light microscopy applications. Chemistry-A European Journal 20 (41), pp. 13162 - 13173 (2014)

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supplementary-material

18.

Journal Article

Agarwal, A.; Zhang, M.; Trembak-Duff, I.; Unterbarnscheidt, T.; Radyushkin, K.; Dibaj, P.; de Souza, D. M.; Boretius, S.; Brzózka, M. M.; Steffens, H. et al.; Berning, S.; Teng, Z.; Gummert, M. N.; Tantra, M.; Guest, P. C.; Willig, K. I.; Frahm, J.; Hell, S. W.; Bahn, S.; Rossner, M. J.; Nave, K. A.; Ehrenreich, H.; Zhang, W.; Schwab, M. H.: Dysregulated expression of Neuregulin-1 by cortical pyramidal neurons disrupts synaptic plasticity. Cell Reports 8 (4), pp. 1130 - 1145 (2014)

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19.

Journal Article

Willig, K. I.; Barrantes, F. J.: Recent applications of superresolution microscopy in neurobiology. Current Opinion in Chemical Biology 20, pp. 16 - 21 (2014)

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20.

Journal Article

Jensen, N. A.; Danzl, J. G.; Willig, K. I.; Lavoie-Cardinal, F.; Brakemann, T.; Hell, S. W.; Jakobs, S.: Coordinate-targeted and coordinate-stochastic super-resolution microscopy with the reversibly switchable fluorescent protein Dreiklang. ChemPhysChem 15 (4), pp. 756 - 762 (2014)

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21.

Journal Article

Willig, K. I.; Steffens, H.; Gregor, C.; Herholt, A.; Rossner, M. J.; Hell, S. W.: Nanoscopy of filamentous actin in cortical dendrites of a living mouse. Biophysical Journal 106 (1), pp. L01 - L03 (2014)

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22.

Journal Article

Eggeling, C.; Willig, K. I.; Barrantes, F.: STED microscopy of living cells - new frontiers in membrane and neurobiology. Journal of Neurochemistry 126 (2), pp. 203 - 212 (2013)

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23.

Journal Article

Eggeling, C.; Willig, K. I.; Barrantes, F. J.: STED microscopy of living cells – new frontiers in membrane and neurobiology. Journal of Neurochemistry 126 (2), pp. 203 - 212 (2013)

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24.

Journal Article

Nizamov, S.; Willig, K. I.; Sednev, M. V.; Belov, V. N.; Hell, S. W.: Phosphorylated 3-heteroarylcoumarins and their use in fluorescence microscopy and nanoscopy. Chemistry-A European Journal 18 (51), pp. 16339 - 16348 (2012)

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25.

Journal Article

Testa, I.; Urban, N.; Jakobs, S.; Eggeling, C.; Willig, K. I.; Hell, S. W.: Nanoscopy of living brain slices with low light levels. Neuron 75 (6), pp. 992 - 1000 (2012)

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26.

Journal Article

Berning, S.; Willig, K. I.; Steffens, H.; Dibaj, P.; Hell, S. W.: Nanoscopy in a living mouse brain. Science 335 (6068), p. 551 - 551 (2012)

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27.

Journal Article

Lalkens, B.; Testa, I.; Willig, K. I.; Hell, S. W.: MRT letter: Nanoscopy of protein colocalization in living cells by STED and GSDIM. Microscopy Research and Technique 75 (1), pp. 1 - 6 (2012)

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28.

Journal Article

Tonnesen, J.; Nadrigny, F.; Willig, K. I.; Wedlich-Söldner, R.; Nägerl, U. V.: Two-color STED microscopy of living synapses using a single laser-beam pair. Biophysical Journal 101 (10), pp. 2545 - 2552 (2011)

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29.

Journal Article

Kleine-Vehn, J.; Wabnik, K.; Martiniere, A.; Langowski, L.; Willig, K.; Naramoto, S.; Leitner, J.; Tanaka, H.; Jakobs, S.; Robert, S. et al.; Luschnig, C.; Govaerts, W.; Hell, S. W.; Runions, J.; Friml, J.: Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane. Molecular Systems Biology 7, 540 (2011)

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30.

Journal Article

Grotjohann, T.; Testa, I.; Leutenegger, M.; Bock, H.; Urban, N.; Lavoie-Cardinal, F.; Willig, K.; Eggeling, C.; Jakobs, S.; Hell, S. W.: Diffraction-unlimited all-optical imaging and writing with a photochromic GFP. Nature 478 (7368), pp. 204 - 208 (2011)

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31.

Journal Article

Urban, N.; Willig, K.; Hell, S. W.: STED nanoscopy of actin dynamics in synapses deep inside living brain slices. Biophysical Journal 101 (5), pp. 1277 - 1284 (2011)

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32.

Journal Article

van den Bogaart, G.; Meyenberg, K.; Risselada, H. J.; Amin, H.; Willig, K.; Hubrich, B. E.; Dier, M.; Hell, S. W.; Grubmüller, H.; Diederichsen, U. et al.; Jahn, R.: Membrane protein sequestering by ionic protein–lipid interactions. Nature 479 (7374), doi:10.1038/nature10545, pp. 552 - 555 (2011)

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33.

Journal Article

Willig, K.; Stiel, A. C.; Brakemann, T.; Jakobs, S.; Hell, S. W.: Dual-label STED nanoscopy of living cells using photochromism. Nano Letters 11 (9), pp. 3970 - 3973 (2011)

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34.

Journal Article

Watanabe, S.; Punge, A.; Hollopeter, G.; Willig, K.; Hobson, R. J.; Davis, M. W.; Hell, S. W.; Jorgensen, E. M.: Protein localization in electron micrographs using fluorescence nanoscopy. Nature methods 8 (1), pp. 80 - 84 (2010)

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35.

Journal Article

Hein, B.; Willig, K.; Wurm, C.; Westphal, V.; Jakobs, S.; Hell, S. W.: Stimulated emission depletion nanoscopy of living cells using SNAP-tag fusion proteins. Biophysical Journal 98 (1), pp. 158 - 163 (2010)

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36.

Journal Article

Han, K. Y.; Willig, K. I.; Rittweger, E.; Jelezko, F.; Eggeling, C.; Hell, S. W.: Three-dimensional stimulated emission depletion microscopy of nitrogen-vacancy centers in diamond using continuous-wave light. Nano Letters 9 (9), pp. 3323 - 3329 (2009)

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37.

Journal Article

Naegerl, U. V.; Willig, K.; Hein, B.; Hell, S. W.; Bonhoeffer, T.: Live-cell imaging of dendritic spines by STED microscopy. Proceedings of the National Academy of Sciences of the United States of America 105 (48), pp. 18982 - 18987 (2008)

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38.

Journal Article

Hein, B.; Willig, K.; Hell, S. W.: Stimulated emission depletion (STED) nanoscopy of a fluorescent protein-labeled organelle inside a living cell. Proceedings of the National Academy of Scienes of the United States of America 105 (38), pp. 14271 - 14276 (2008)

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39.

Journal Article

Willig, K.; Harke, B.; Medda, R.; Hell, S. W.: STED microscopy with continuous wave beams. Nature Methods 4 (11), pp. 915 - 918 (2007)

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40.

Journal Article

Sieber, J. J.; Willig, K. I.; Kutzner, C.; Gerding-Reimers, C.; Harke, B.; Donnert, G.; Rammner, B.; Eggeling, C.; Hell, S. W.; Grubmüller, H. et al.; Lang, T.: Anatomy and dynamics of a supramolecular membrane protein cluster. Science 317 (5841), pp. 1072 - 1076 (2007)

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41.

Journal Article

Baier, C. J.; Kellner, R.; Borroni, V.; Willig, K.; Garbus, I.; Hell, S. W.; Barrantes, F. J.: Cholesterol modulates acetylcholine receptor organization and stability at the cell membrane. Journal of Neurochemistry 102 (Suppl. 1), pp. 24 - 25 (2007)

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42.

Journal Article

Kellner, R. ..; Baier, J.; Willig, K.; Hell, S. W.; Barrantes, F. J.: Nanoscale organization of nicotinic acetylcholine receptors revealed by stimulated emission depletion microscopy. Neuroscience 144 (1), pp. 135 - 143 (2007)

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43.

Journal Article

Fitzner, D.; Schneider, A.; Kippert, W.; Moebius, W.; Willig, K.; Hell, S. W.; Bunt, G.; Gaus, K.; Simons, M.: Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin. EMBO Journal 25 (21), pp. 5037 - 5048 (2006)

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44.

Journal Article

Willig, K. I.; Kellner, R.; Medda, R.; Hein, B.; Jakobs, S.; Hell, S. W.: Nanoscale resolution in GFP-based microscopy. Nature Methods 3 (9), pp. 721 - 723 (2006)

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45.

Journal Article

Willig, K.; Keller, J.; Bossi, M.; Hell, S. W.: STED-microscopy resolves nanoparticle assemblies. New Journal of Physics 8, 106 (2006)

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46.

Journal Article

Kittel, R. J.; Wichmann, C.; Rasse, T. M.; Fouquet, W.; Schmidt, M.; Schmid, A.; Wagh, D. A.; Pawlu, C.; Kellner, R.; Willig, K. et al.; Hell, S. W.; Buchner, E.; Heckmann, M.; Sigrist, S. J.: Bruchpilot promotes active zone assembly, Ca2+-channel clustering, and vesicle release. Science 312, pp. 1051 - 1054 (2006)

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47.

Journal Article

Willig, K.; Rizzoli, S. O.; Westphal, V.; Jahn, R.; Hell, S. W.: STED-microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature 440, pp. 935 - 939 (2006)

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48.

Journal Article

Sieber, J.; Willig, K.; Heintzmann, R.; Hell, S. W.; Lang, T.: The SNARE-motif is essential for the formation of syntaxin clusters in the plasma membrane. Biophysical Journal 90 (8), pp. 2843 - 2851 (2006)

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49.

Journal Article

Hell, S. W.; Willig, K.; Westphal, V.: Fluoreszenzmikroskopie ohne Beugungsgrenze. Biospektrum 12 (5), pp. 492 - 494 (2006)

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Book Chapter (1)

50.

Book Chapter

Hell, S. W.; Willig, K.; Dyba, M.; Jakobs, S.; Kastrup, L.; Westphal, V.: Nanoscale resolution with focused light: STED and other RESOLFT microscopy concepts. In: Handbook of biological confocal microscopy, pp. 571 - 579 (Ed. Pawley, J.B.). Springer, New York (2006)

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