Publications of Holger Taschenberger

Lin, K.-H.; Ranjan, M.; Lipstein, N.; Brose, N.; Neher, E.; Taschenberger, H.: Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short‐term plasticity. The Journal of Physiology (2025)

Zeppillo, T.; Ali, H.; Ravichandran, S.; Ritter, T. C.; Wenger, S.; López-Murcia, F. J.; Gideons, E.; Signorelli, J.; Schmeisser, M. J.; Wiltfang, J. et al.; Rhee, J. S.; Brose, N.; Taschenberger, H.; Krüger-Burg, D. D.: Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA_ARs and cytosolic gephyrin aggregation. Communications Biology 7, 1157 (2024)

López-Murcia, F. J.; Lin, K.-H.; Berns, M. M. M.; Ranjan, M.; Lipstein, N.; Neher, E.; Brose, N.; Reim, K.; Taschenberger, H.: Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion. PNAS 121 (15), e2320505121 (2024)

Weichard, I.; Taschenberger, H.; Gsell, F.; Bornschein, G.; Ritzau-Jost, A.; Schmidt, H.; Kittel, R. J.; Eilers, J.; Neher, E.; Hallermann, S. et al.; Nerlich, J.: Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons. Proceedings of the National Academy of Sciences of the United States of America 120 (43), e2305460120 (2023)

Eisner, D.; Neher, E.; Taschenberger, H.; Smith, G.: Physiology of intracellular calcium buffering. Physiological Reviews 103 (4), pp. 2767 - 2845 (2023)

Singh, M.; Zhao, Y.; Daguano Gastaldi, V.; Wojcik, S. M.; Curto, Y.; Kawaguchi, R.; Merino, R.M.; Garcia-Agudo, L. F.; Taschenberger, H.; Brose, N. et al.; Geschwind, D.; Nave, K.-A.; Ehrenreich, H.: Erythropoietin re-wires cognition-associated transcriptional networks. Nature Communications 14, 4777 (2023)

Platzer, K.; Sticht, H.; Bupp, C.; Ganapathi, M.; Pereira, E. M.; Le Guyader, G.; Bilan, F.; Henderson, L. B.; Lemke, J. R.; Taschenberger, H. et al.; Brose, N.; Jamra, R. A.; Wojcik, S. M.: De Novo Missense Variants in SLC32A1 Cause a Developmental and Epileptic Encephalopathy Due to Impaired GABAergic Neurotransmission. Annals of Neurology 92 (6), pp. 958 - 973 (2022)

Keine, C.; Al-Yaari, M.; Radulovic, T.; Thomas, C. I.; Ramos, P. V.; Guerrero-Given, D.; Ranjan, M.; Taschenberger, H.; Kamasawa, N.; Young Jr., S. M.: Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming. eLife 11, e81505 (2022)

Lin, K.-H.; Taschenberger, H.; Neher, E.: A sequential two-step priming scheme reproduces diversity in synaptic strength and short-term plasticity. Proceedings of the National Academy of Sciences of the United States of America 119, e2207987119 (2022)

Lipstein, N.; Chang, S.; Lin, K.-H.; López-Murcia, F. J.; Neher, E.; Taschenberger, H.; Brose, N.: Munc13-1 is a Ca²⁺-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission. Neuron 109 (24), pp. 3980 - 4000.e7 (2021)

Neher, E.; Taschenberger, H.: Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States. Neuroscience 458, pp. 182 - 202 (2021)

Imig, C.; López-Murcia, F. J.; Maus, L.; García-Plaza, I. H.; Mortensen, L.-S.; Schwark, M.; Schwarze, V.; Angibaud, J.; Nägerl, U. V.; Taschenberger, H. et al.; Brose, N.; Cooper, B. H.: Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices. Neuron 108 (5), pp. 843 - 860.e8 (2020)

López-Murcia, F. J.; Reim, K.; Jahn, O.; Taschenberger, H.; Brose, N.: Acute complexin knockout abates spontaneous and evoked transmitter release. Cell Reports 26 (10), pp. 2521 - 2530.e5 (2019)

Babaev, O.; Cruces-Solís, H.; Piletti Chatain, C.; Hammer, M.; Wenger, S.; Ali, H.; Karalis, N.; de Hoz, L.; Schlüter , O. M.; Yanagawa, Y. et al.; Ehrenreich, H.; Taschenberger, H.; Brose, N.; Krueger-Burg, D.: IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses. Nature Communications 9 (1), 5400 (2018)

Lin, K. H.; Taschenberger, H.; Neher, E.: Dynamics of volume-averaged intracellular Ca²⁺ in a rat CNS nerve terminal during single and repetitive voltage-clamp depolarizations. Journal of Physiology 595 (10), pp. 3219 - 3236 (2017)

Lipstein, N.; Verhoeven-Duif, N. M.; Michelassi, F. E.; Calloway, N.; van Hasselt, P. M.; Pienkowska, K.; van Haaften, G.; van Haelst, M. M.; van Empelen, R.; Cuppen, I. et al.; van Teeseling, H. C.; Evelein, A. M. V.; Vorstman, J. A.; Thoms, S.; Jahn, O.; Duran, K. J.; Monroe, G. R.; Ryan, T. A.; Taschenberger, H.; Dittman, J. S.; Rhee, J.; Visser, G.; Jans, J. J.; Brose, N.: Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of Clinical Investigation 127 (3), pp. 1005 - 1018 (2017)

Taschenberger, H.; Woehler, A.; Neher, E.: Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength. Proceedings of the National Academy of Sciences of the United States of America 113 (31), pp. E4548 - E4557 (2016)

Oliveira, L. M. A.; Falomir, L. J.; Gralle Botelho, M.; Lin, K. H.; Wales, P.; Koch, J.; Gerhardt, E.; Taschenberger, H.; Outeiro, T. F.; Lingor, P. et al.; Schüle, B.; Arndt-Jovin, D. J.; Jovin, T. M.: Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells. Cell Death and Disease 6, e1994 (2015)

Chang, S.; Reim, K.; Pedersen, M.; Neher, E.; Brose, N.; Taschenberger, H.: Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse. Journal of Neuroscience 35 (21), pp. 8272 - 8290 (2015)

Chang, S.; Reim, K.; Pedersen, M.; Neher, E.; Brose, N.; Taschenberger, H.: Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse. The Journal of Neuroscience 35 (21), pp. 8272 - 8290 (2015)