Publications of Kathrin Kusch

Asadollahi, E.; Trevisiol, A.; Saab, A. S.; Looser, Z. J.; Dibaj, P.; Ebrahimi, R.; Kusch, K.; Ruhwedel, T.; Möbius, W.; Jahn, O. et al.; Lee, J. Y.; Don, A. S.; Khalil, M.-A.; Hiller, K.; Baes, M.; Weber, B.; Abel, E. D.; Ballabio, A.; Popko, B.; Kassmann, C. M.; Ehrenreich, H.; Hirrlinger, J.; Nave, K.-A.: Oligodendroglial fatty acid metabolism as a central nervous system energy reserve. Nature Neuroscience 27, pp. 1934 - 1944 (2024)

Späte, E.; Zhou, B.; Sun, T.; Kusch, K.; Asadollahi, E.; Siems, S. B.; Depp, C.; Werner, H. B.; Saher, G.; Hirrlinger, J. et al.; Möbius, W.; Nave, K.-A.; Göbbels, S.: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia 72 (8), pp. 1374 - 1391 (2024)

Jablonska, B.; Adams, K. L.; Kratimenos, P.; Li, Z.; Strickland, E.; Haydar, T. F.; Kusch, K.; Nave, K.-A.; Gallo, V.: Sirt2 promotes white matter oligodendrogenesis during development and in models of neonatal hypoxia. Nature Communications 13, 4771 (2022)

Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K.; Jahn, O.; Piepkorn, L.; Agüi-Gonzalez, P.; Phan, N. T. N.; Ruhwedel, T.; Sadowski, B. et al.; Rizzoli, S. O.; Werner, H. B.; Ehrenreich, H.; Nave, K.-A.; Möbius, W.: White matter integrity in mice requires continuous myelin synthesis at the inner tongue. Nature Communications 13, 1163 (2022)

Trevisiol, A.; Kusch, K.; Steyer, A. M.; Gregor, I.; Nardis, C.; Winkler, U.; Köhler, S.; Restrepo, A.; Möbius, W.; Werner, H. B. et al.; Nave, K.-A.; Hirrlinger, J.: Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia. PLoS Biology 18 (11), e3000943 (2020)

Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A.; Tzvetanova, I.; Battefeld, A.; Kusch, K.; Kole, M. H. P.; Strenzke, N.; Möbius, W. et al.; de Hoz, L.; Nave, K.-A.: A role of oligodendrocytes in information processing. Nature Communications 11 (1), 5497 (2020)

Eichel, M. A.; Gargareta, V.-I.; D’Este, E.; Fledrich, R.; Kungl, T.; Buscham, T. J.; Lüders, K. A.; Miracle, C.; Jung, R. B.; Distler, U. et al.; Kusch, K.; Möbius, W.; Hülsmann, S.; Tenzer, S.; Nave, K.-A.; Werner, H. B.: CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves. Nature Communications 11 (1), 4514 (2020)

Jahn, O.; Siems, S. B.; Kusch, K.; Hesse, D.; Jung, R. B.; Liepold, T.; Uecker, M.; Sun, T.; Werner, H. B.: The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay. Frontiers in Cellular Neuroscience 14, 249 (2020)

Siems, S. B.; Jahn, O.; Eichel, M. A.; Kannaiyan, N.; Wu, L. M. N.; Sherman, D. L.; Kusch, K.; Hesse, D.; Jung, R. B.; Fledrich, R. et al.; Sereda, M. W.; Rossner, M. J.; Brophy, P. J.; Werner, H. B.: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. eLife 9, e51406 (2020)

Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A.; Spieth, L.; Düking, T.; Schneider, L. V.; Schlaphoff, L.; Dreha-Kulaczewski, S.; Bley, A.; Burfeind, D. et al.; Kusch, K.; Mitkovski, M.; Ruhwedel, T.; Guder, P.; Röhse, H.; Denecke, J.; Gärtner, J.; Möbius, W.; Nave, K.-A.; Saher, G.: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica 138, pp. 147 - 161 (2019)

Fledrich, R.; Akkermann, D.; Schütza, V.; Abdelaal, T. A. M.; Hermes, D.; Schäffner, E.; Soto Bernardini, M. C.; Götze, T.; Klink, A.; Kusch, K. et al.; Krueger, M.; Kungl, T.; Frydrychowicz, C.; Möbius, W.; Brück, W.; Mueller, W. C.; Bechmann, I.; Sereda, M. W.; Schwab, M. H.; Nave, K.-A.; Stassart, R. M.: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies. Nature Communications 10, 1467 (2019)

Lüders, K. A.; Nessler, S.; Kusch, K.; Patzig, J.; Jung, R. B.; Möbius, W.; Nave, K.-A.; Werner, H. B.: Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons. Glia 67 (4), pp. 634 - 649 (2019)

Erwig, M. S.; Patzig, J.; Steyer, A. M.; Dibaj, P.; Heilmann, M.; Heilmann, I.; Jung, R. B.; Kusch, K.; Möbius, W.; Jahn, O. et al.; Nave, K.-A.; Werner, H. B.: Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin. eLife 8, e43888 (2019)

Berghoff, S. A.; Düking, T.; Spieth, L.; Winchenbach, J.; Stumpf, S. K.; Gerndt, N.; Kusch, K.; Ruhwedel, T.; Möbius, W.; Saher, G.: Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model. Acta Neuropathologica Communications 5, 94 (2017)

Trevisiol, A.; Saab, A. S.; Winkler, U.; Marx, G.; Imamura, H.; Möbius, W.; Kusch, K.; Nave, K.-A.; Hirrlinger, J.: Monitoring ATP dynamics in electrically active white matter tracts. eLife 6, e24241 (2017)

Kusch, K.; Uecker, M.; Liepold, T.; Möbius, W.; Hoffmann, C.; Neumann, H.; Werner, H. B.; Jahn, O.: Partial immunoblotting of 2D-gels: a novel method to identify post-translationally modified proteins exemplified for the myelin acetylome. Proteomes 5 (1), 3 (2017)

Patzig, J.; Erwig, M. S.; Tenzer, S.; Kusch, K.; Dibaj, P.; Möbius, W.; Goebbels, S.; Schaeren-Wiemers, N.; Nave, K.-A.; Werner, H. B.: Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction. eLife 5, e17119 (2016)

Saab, A. S.; Tzvetanova, I. D.; Trevisiol, A.; Baltan, S.; Dibaj, P.; Kusch, K.; Möbius, W.; Goetze, B.; Jahn, H. M.; Huang, W. et al.; Steffens, H.; Schomburg, E. D.; Pérez-Samartín, A.; Pérez-Cerdá, F.; Bakhtiari, D.; Matute, C.; Löwel, S.; Griesinger, C.; Hirrlinger, J.; Kirchhoff, F.; Nave, K.-A.: Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism. Neuron 91 (1), pp. 119 - 132 (2016)

Patzig, J.; Kusch, K.; Fledrich, R.; Eichel, M. A.; Lüders, K. A.; Möbius, W.; Sereda, M. W.; Nave, K.-A.; Martini, R.; Werner, H. B.: Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking. Glia 64 (1), pp. 155 - 174 (2016)

Monasterio-Schrader, P. d.; Patzig, J.; Möbius, W.; Barrette, B.; Wagner, T. L.; Kusch, K.; Edgar, J. M.; Brophy, P. J.; Werner, H. B.: Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. Glia 61 (11), pp. 1832 - 1847 (2013)