Publications of H. Urlaub

De, I.; Bessonov, S.; Hofele, R.; Dos Santos, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: The RNA helicase ​Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 22 (2), pp. 138 - 144 (2015)

Lugassy, J.; Corso, J.; Beach, D.; Petrik, T.; Oellerich, T.; Urlaub, H.; Yablonski, D.: Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. Cellular Signalling 27 (1), pp. 125 - 134 (2015)

Hrle, A.; Maier, L. K.; Sharma, K.; Ebert, J.; Basquin, C.; Urlaub, H.; Marchfelder, A.; Conti, E.: Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA Biology 11 (8), pp. 1072 - 1082 (2014)

Petrova, D. T.; Schultze, F. C.; Brandhorst, G.; Luchs, K. D.; Lenz, C.; Urlaub, H.; Rubel, D.; Gross, O.; Walson, P. D.; Oellerich, M.: Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice. Proteome Science 12, 56 (2014)

Staals, R. H.; Zhu, Y.; Taylor, D. W.; Kornfeld, J. E.; Sharma, K.; Barendregt, A.; Koehorst, J. F.; Vlot, M.; Neupane, N.; Varossieau, K. et al.; Sakamoto, K.; Suzuki, T.; Dohmae, N.; Yokoyama, S.; Schaap, P. J.; Urlaub, H.; Heck, A. J. R.; Nogales, E.; Doudna, J. A.; Shinkai, A.; van der Oost, J.: RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell 56 (4), pp. 518 - 530 (2014)

Kramer, K.; Sachsenberg, T.; Beckmann, B. M.; Qamar, S.; Boon, K. L.; Hentze, M. W.; Kohlbacher, O.; Urlaub, H.: Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins. Nature Methods 11 (10), pp. 1064 - 1070 (2014)

Lenz, C.; Urlaub, H.: Separation methodology to improve proteome coverage depth. Expert Review of Proteomics 11 (4), pp. 409 - 414 (2014)

Moritz, B.; Lilie, H.; Naarmann-de Vries, I. S.; Urlaub, H.; Wahle, E.; Ostareck-Lederer, A.; Ostareck, D. H.: Biophysical and biochemical analysis of hnRNP K: Arginine methylation, reversible aggregation and combinatorial binding to nucleic acids. Biological Chemistry 395 (7-8), pp. 837 - 853 (2014)

Wilhelm, B. G.; Mandad, S.; Truckenbrodt, S.; Kröhnert, K.; Schäfer, C.; Rammner, B.; Koo, S. J.; Classen, G. A.; Krauss, M.; Haucke, V. et al.; Urlaub, H.; Rizzoli, S. O.: Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science 344 (6187), pp. 1023 - 1028 (2014)

Vazquez-Pianzola, P.; Adam, J.; Haldemann, D.; Hain, D.; Urlaub, H.; Suter, B.: Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D. Development 141 (9), pp. 1915 - 1926 (2014)

Loedige, I.; Stotz, M.; Qamar, S.; Kramer, K.; Hennig, J.; Schubert, T.; Löffler, P.; Längst, G.; Merkl, R.; Urlaub, H. et al.; Meister, G.: The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Genes and Development 28 (7), pp. 749 - 764 (2014)

Plagens, A.; Tripp, V.; Daume, M.; Sharma, K.; Klingl, A.; Hrle, A.; Conti, E.; Urlaub, H.; Randau, L.: In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex. Nucleic Acids Research 42 (8), pp. 5125 - 5138 (2014)

Brendel, J.; Stoll, B.; Lange, S. J.; Sharma, K.; Lenz, C.; Stachler, A. E.; Maier, L. K.; Richter, H.; Nickel, L.; Schmitz, R. A. et al.; Randau, L.; Allers, T.; Urlaub, H.; Backofen, R.; Marchfelder, A.: A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii. Journal of Biological Chemistry 289 (10), pp. 7164 - 7177 (2014)

Schmidt, C.; Groenborg, M.; Deckert, J.; Bessonov, S.; Conrad, T.; Lührmann, R.; Urlaub, H.: Mass spectrometry–based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA 20 (3), pp. 406 - 420 (2014)

Biesemann, C.; Groenborg, M.; Luquet, E.; Wichert, S. P.; Bernard, V.; Bungers, S. R.; Cooper, B.; Varoqueaux, F.; Li, L.; Byrne, J. A. et al.; Urlaub, H.; Jahn, O.; Brose, N.; Herzog, E.: Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO Journal 33 (2), pp. 157 - 170 (2014)

Xiang, S. Q.; Gapsys, V.; Kim, H. Y.; Bessonov, S.; Hsiao, H. H.; Möhlmann, S.; Klaukien, V.; Ficner, R.; Becker, S.; Urlaub, H. et al.; Lührmann, R.; de Groot, B.; Zweckstetter, M.: Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 21 (12), pp. 2162 - 2174 (2013)

Engelke, M.; Oellerich, T.; Dittmann, K.; Hsiao, H. H.; Urlaub, H.; Serve, H.; Griesinger, C.; Wienands, J.: Cutting edge: Feed-forward activation of phospholipase C gamma 2 via C2 domain-mediated binding to SLP65. Journal of Immunology 191 (11), pp. 5354 - 5358 (2013)

Pilla, E.; Kilisch, M.; Lenz, C.; Urlaub, H.; Geiss-Friedlander, R.: The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. Journal of Biological Chemistry 288 (45), pp. 32787 - 32796 (2013)

Bhaskar, V.; Roudko, V.; Basquin, J.; Sharma, K.; Urlaub, H.; Seraphin, B.; Conti, E.: Structure and RNA-binding properties of the Not1-Not2Not5 module of the yeast Ccr4-Not complex. Nature Structrural and Molecular Biology 12 (20), pp. 1281 - 1288 (2013)

Wirth, M.; Karaca, S.; Wenzel, D.; Ho, L.; Tishkoff, D.; Lombard, D. B.; Verdin, E.; Urlaub, H.; Jedrusik-Bode, M.; Fischle, W.: Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion 13 (6), pp. 705 - 720 (2013)