Publications of Tiago F. Outeiro

Journal Article (56)

1.
Journal Article
Oliveira, L. M. A.; Gasser, T.; Edwards, R.; Zweckstetter, M.; Melki, R.; Stefanis, L.; Lashuel, H. A.; Sulzer, D.; Vekrellis, K.; Halliday, G. M. et al.; Tomlinson, J. J.; Schlossmacher, M.; Jensen, P. H.; Schulze-Hentrich, J.; Riess, O.; Hirst, W.D.; El-Agnaf, O.; Mollenhauer, B.; Lansbury, P.; Outeiro, T. F.: Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)
2.
Journal Article
Masaracchia, C.; Koenig, A.; Valiente-Gabioud, A. A.; Peralta, P.; Favretto, F.; Strohäker, T.; Lazaro, D. F.; Zweckstetter, M.; Fernandez, C. O.; Outeiro, T. F.: Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2020)
3.
Journal Article
Vaz, R.; Chapela, D.; Coelho, J.; Lopez, L.; Ferreira, J.; Alfonso, N.; Sousa, S.; Outeiro, T. F.: Tapentadol Prevent Motor Impairments in a Mouse Model of Dyskinesia. Neuroscience 404, pp. 58 - 71 (2020)
4.
Journal Article
Szegö, É. M.; Dominguez-Meijide, A.; Gerhardt, E.; König, A.; Koss, D. J.; Li, W.; Pinho, R.; Fahlbusch, C.; Johnson, M.; Santos, P. et al.; Villar-Piqué, A.; Thom, T.; Rizzoli, S.; Schmitz, M.; Li, J.; Zerr, I.; Attems, J.; Jahn, O.; Outeiro, T. F.: Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 28, pp. 65 - 77 (2019)
5.
Journal Article
Outeiro, T. F.; Harvey, K.; Dominguez-Meijide, A.; Gerhardt, E.: LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? Biochemical Society Transactions 47, pp. 827 - 838 (2019)
6.
Journal Article
Rossetti, G.; Kless, A.; Lai, L.; Outeiro, T. F.; Carloni, P.: Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions 47, pp. 909 - 918 (2019)
7.
Journal Article
Wu, J.; Ardah, M.; Haikal, C.; Svanbergsson, A.; Diepenbroek, M.; Vaikath, N. N.; Li, W.; Wang, Z.-Y.; Outeiro, T. F.; El-Agnaf, O. M. et al.; Li, J.-Y.: Dihydromyricetin and salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Translational neurodegeneration 8, 18 (2019)
8.
Journal Article
Candelise, N.; Schmitz, M.; Llorens, F.; Villar-Piqué, A.; Cramm, M.; Thom, T.; da Silva Correia, S. M.; Gomes da Cunha, J. E.; Möbius, W.; Outeiro, T. F. et al.; González Álvarez, V.; Banchelli, M.; D'Andrea, C.; de Angelis, M.; Zafar, S.; Rabano, A.; Matteini, P.; Zerr, I.: Seeding variability of different alpha synuclein strains in synucleinopathies. Annals of Neurology 85 (5), pp. 691 - 703 (2019)
9.
Journal Article
Vasili, E.; Dominguez-Meijide, A.; Outeiro, T. F.: Spreading of α-synuclein and tau: a systematic comparison of the mechanisms involved. Frontiers in Molecular Neuroscience 12, 107 (2019)
10.
Journal Article
Harvey, K.; Outeiro, T. F.: The role of LRRK2 in cell signalling. Biochemical Society Transactions 47, pp. 197 - 207 (2019)
11.
Journal Article
Carija, A.; Pinheiro, F.; Pujols, J.; Brás, I. C.; Fernandes Lázaro, D.; Santambrogio, C.; Grandori, R.; Outeiro, T. F.; Navarro, S.; Ventura, S.: Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity. Redox biology 22, 101135 (2019)
12.
Journal Article
Outeiro, T. F.; Koss, D. J.; Erskine, D.; Walker, L.; Kurzawa-Akanbi, M.; Burn, D.; Donaghy, P.; Morris, C.; Taylor, J.-P.; Thomas, A. et al.; Atterns, J.; McKeith, I.: Dementia with Lewy bodies: an update and outlook. Molecular neurodegeneration 14, 5 (2019)
13.
Journal Article
Chiang, A. N.; Liang, M.; Dominguez-Meijide, A.; Masaracchia, C.; Goeckeler-Fried, J. L.; Mazzone, C. S.; Newhouse, D. W.; Kendsersky, N. M.; Yates, M. E.; Manos-Turvey, A. et al.; Needham, P. G.; Outeiro, T. F.; Wipf, P.; Brodsky, J. L.: Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry 27 (1), pp. 79 - 91 (2019)
14.
Journal Article
Pinho , R.; Paiva, I.; Jercic, K. G.; Fonseca-Ornelas, L.; Gerhardt, E.; Fahlbusch, C.; Garcia-Esparcia, P.; Kerimoglu, C.; Pavlou, M. A.S.; Villar-Piqué, A. et al.; Szegö, É.; Lopes da Fonseca, T.; Odoardi, F.; Soeroes, S.; Rego, A. C.; Fischle, W.; Schwamborn, J. C.; Meyer, T.; Kügler, S.; Ferrer, I.; Attems, J.; Fischer, A.; Becker, S.; Zweckstetter, M.; Borovecki, F.; Outeiro, T. F.: Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein. Human Molecular Genetics 28 (1), pp. 31 - 50 (2019)
15.
Journal Article
Prasad, V.; Wasser, Y.; Hans, F.; Goswami, A.; Katona, I.; Outeiro, T. F.; Kahle, P. J.; Schulz, J. B.; Voigt, A.: Monitoring α-synuclein multimerization in vivo. The FASEB Journal 33 (2), pp. 2116 - 2131 (2019)
16.
Journal Article
Brás, I. C.; Tenreiro, S.; Silva, A. M.; Outeiro, T. F.: Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research 18 (8), 10.1093/femsyr/foy108 (2018)
17.
Journal Article
Brás, I. C.; Lopes, L. V.; Outeiro, T. F.: Sensing α-Synuclein from the outside via the prion problem: implications for neurodegeneration. Movement Disorders 33 (11), pp. 1675 - 1684 (2018)
18.
Journal Article
Gustafsson, G.; Lööv, C.; Persson, E.; Lázaro, D. F.; Takeda, S.; Bergström, J.; Erlandsson, A.; Sehlin, D.; Balaj, L.; György, B. et al.; Hallbeck, M.; Outeiro, T. F.; Breakefield, X. O.; Hyman, B. T.; Ingelsson, M.: Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells. Cellular and Molecular Neurobiology 38, pp. 1539 - 1550 (2018)
19.
Journal Article
Magalhães, R. S.S.; Popova, B.; Braus, G. H.; Outeiro, T. F.; Eleutherio, E. C.A.: The trehalose protective mechanism during thermal stress in Saccharomyces cerevisiae: the roles of Ath1 and Agt1. FEMS Yeast Research 18 (6), foy066 (2018)
20.
Journal Article
Masaracchia, C.; Hnida, M.; Gerhardt, E.; Lopes da Fonseca, T.; Villar-Pique, A.; Branco, T.; Stahlberg, M. A.; Dean, C.; Fernández, C. O.; Milosevic, I. et al.; Outeiro, T. F.: Membrane binding, internalization, and sorting of alpha-synuclein in the cell. Acta Neuropathologica Communications 6, 79 (2018)
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