Journal Article (30)
1.
Journal Article
13, 141 (2023)
APP family member dimeric complexes are formed predominantly in synaptic compartments. Cell & Bioscience 2.
Journal Article
11, 87 (2023)
Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity. Acta Neuropathologica Communications 3.
Journal Article
11 (21), 3421 (2022)
The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer’s Disease. Cells 4.
Journal Article
403 (1), pp. 43 - 71 (2022)
Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer’s disease. Biological Chemistry 5.
Journal Article
403 (1), pp. 3 - 26 (2022)
The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research. Biological Chemistry 6.
Journal Article
3, pp. 281 - 287 (2021)
Heterologous production of a cyanobacterial bacteriocin with potent antibacterial activity. Current Research in Biotechnology 7.
Journal Article
77, pp. 5223 - 5242 (2020)
The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif. Cellular and Molecular Life Sciences 8.
Journal Article
26 (3), pp. 185 - 186 (2020)
Forschungskolleg “NeurodegX”. Neuroforum 9.
Journal Article
151 (5), pp. 626 - 641 (2019)
Copper and zinc ions govern the trans‐directed dimerization of APP family members in multiple ways. Journal of Neurochemistry 10.
Journal Article
55, pp. 5809 - 5829 (2018)
Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin. Molecular Neurobiology 11.
Journal Article
75, pp. 301 - 322 (2018)
Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA. Cellular and Molecular Life Sciences 12.
Journal Article
37 (21), pp. 5345 - 5365 (2017)
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission. The Journal of Neuroscience 13.
Journal Article
10, 140 (2017)
Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction. Frontiers in Molecular Neuroscience 14.
Journal Article
10, 118 (2017)
LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State. Frontiers in Molecular Neuroscience 15.
Journal Article
8, 410 (2014)
Shedding of APP limits its synaptogenic activity and cell adhesion properties. Frontiers in Cellular Neuroscience 16.
Journal Article
34 (33), pp. 11159 - 11172 (2014)
Amyloid Precursor Protein Dimerization and Synaptogenic Function Depend on Copper Binding to the Growth Factor-Like Domain. The Journal of Neuroscience 17.
Journal Article
248, pp. 441 - 450 (2013)
Age-dependent increases in tau phosphorylation in the brains of type 2 diabetic rats correlate with a reduced expression of p62. Experimental Neurology 18.
Journal Article
8 (5), p. e64149 (2013)
A New Mint1 Isoform, but Not the Conventional Mint1, Interacts with the Small GTPase Rab6. PLoS One 19.
Journal Article
33 (39), pp. 15596 - 15602 (2013)
Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice. The Journal of Neuroscience 20.
Journal Article
51 (1-2), pp. 43 - 52 (2012)
Amyloid precursor protein (APP) regulates synaptic structure and function. Molecular and Cellular Neuroscience 21.
Journal Article
217, pp. 389 - 395 (2012)
Structural aspects and physiological consequences of APP/APLP trans-dimerization. Experimental Brain Research 22.
Journal Article
69, pp. 1353 - 1375 (2012)
APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms. Cellular and Molecular Life Sciences 23.
Journal Article
49 (4), pp. 448 - 455 (2012)
Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Molecular and Cellular Neuroscience 24.
Journal Article
286 (46), pp. 39804 - 39812 (2011)
Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length. Journal of Biological Chemistry 25.
Journal Article
284 (42), pp. 28943 - 28952 (2009)
Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-β Protein Production. Journal of Biological Chemistry 26.
Journal Article
281 (52), pp. 40114 - 40123 (2006)
PAT1a Modulates Intracellular Transport and Processing of Amyloid Precursor Protein (APP), APLP1, and APLP2. Journal of Biological Chemistry 27.
Journal Article
24, pp. 3624 - 3634 (2005)
Homo- and heterodimerization of APP family members promotes intercellular adhesion. The EMBO Journal 28.
Journal Article
279 (18), pp. 18146 - 18156 (2004)
The Proteolytic Processing of the Amyloid Precursor Protein Gene Family Members APLP-1 and APLP-2 Involves α-, β-, γ-, and ϵ-Like Cleavages. Journal of Biological Chemistry 29.
Journal Article
42 (22), pp. 6664 - 6673 (2003)
γ-Secretase Cleavage and Binding to FE65 Regulate the Nuclear Translocation of the Intracellular C-Terminal Domain (ICD) of the APP Family of Proteins. Biochemistry 30.
Journal Article
41 (8), pp. 2825 - 2835 (2002)
A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing. Biochemistry Preprint (1)
31.
Preprint
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease. bioRxiv (2023)