Publications of the MPI of Experimental Medicine until 2021

Merino, R. M.; Leon-Pinzon, C.; Stuehmer, W.; Möck, M.; Staiger, J. F.; Wolf, F.; Neef, A.: Theta activity paradoxically boosts gamma and ripple frequency sensitivity in prefrontal interneurons. Proceedings of the National Academy of Sciences of the USA 118 (51), e2114549118 (2021)

Segelcke, D.; Fischer, H. K.; Hütte, M.; Dennerlein, S.; Benseler, F.; Brose, N.; Pogatzki-Zahn, E. M.; Schmidt, M.: Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice. Cell Reports 37 (12), 110152 (2021)

Lipstein, N.; Chang, S.; Lin, K.-H.; López-Murcia, F. J.; Neher, E.; Taschenberger, H.; Brose, N.: Munc13-1 is a Ca²⁺-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission. Neuron 109 (24), pp. 3980 - 4000.e7 (2021)

Arinrad, S.; Wilke, J. B. H.; Seelbach, A.; Doeren, J.; Hindermann, M.; Butt, U. J.; Steixner-Kumar, A. A.; Spieth, L.; Ronnenberg, A.; Pan, H. et al.; Berghoff, S. A.; Hollmann, M.; Lüder, F.; Nave, K.-A.; Bechter, K.; Ehrenreich, H.: NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Molecular Psychiatry 27, pp. 4974 - 4983 (2021)

Boehm, U.; Nelson, G.; Brown, C. M.; Bagley, S.; Bajcsy, P.; Bischof, J.; Dauphin, A.; Dobbie, I. M.; Eriksson, J. E.; Faklaris, O. et al.; Fernandez-Rodriguez, J.; Ferrand, A.; Gelman, L.; Gheisari, A.; Hartmann, H.; Kukat, C.; Laude, A.; Mitkovski, M.; Munck, S.; North, A. J.; Rasse, T. M.; Resch-Genger, U.; Schuetz, L. C.; Seitz, A.; Strambio-De-Castillia, C.; Swedlow, J. R.; Nitschke, R.: QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy. Nature Methods 18 (12), pp. 1424 - 1427 (2021)

Edgar, J. M.; McGowan, E.; Chapple, K. J.; Möbius, W.; Lemgruber, L.; Insall, R. H.; Nave, K.-A.; Boullerne, A.: Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin. Journal of Anatomy 239 (6), pp. 1241 - 1255 (2021)

Vieira, A. M.; Zahed, F.; Crispim, A. C.; de Souza Bento, E.; de Freitas Oliveira França, R.; Pinheiro, I. O.; Pardo, L. A.; Carvalho, B. M.: Production of levan from Bacillus subtilis var. natto and apoptotic effect on SH-SY5Y neuroblastoma cells. Carbohydrate Polymers 273, 118613 (2021)

Ni, G.; Zeng, J.; Revez, J.A.; Wang, Y.; Zheng, Z.; Ge, T.; Restuadi, R.; Kiewa, J.; Nyholt, D.R.; Coleman, J.R.I. et al.; Smoller, J.W.; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Ehrenreich, H.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Yang, J.; Visscher, P. M.; Wray, N. R.: A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. Biological Psychiatry 90 (9), pp. 611 - 620 (2021)

Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L.; Depp, C.; Sasmita, A. O.; Vasileva, M. H.; Scholz, P.; Zhao, Y.; Krüger, D. et al.; Wichert, S.; Brown, E. R.; Michail, K.; Nave, K.-A.; Bonn, S.; Odoardi, F.; Rossner, M.; Ischebeck, T.; Edgar, J. M.; Saher, G.: Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Reports 37 (4), 109889 (2021)

Bergner, C. G.; Genc, N.; Hametner, S.; Franz, J.; van der Meer, F.; Mitkovski, M.; Weber, M. S.; Stoltenburg-Didinger, G.; Kühl, J.-S.; Köhler, W. et al.; Brück, W.; Gärtner, J.; Stadelmann, C.: Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis. Glia 69 (10), pp. 2362 - 2377 (2021)

Nelson, G.; Boehm, U.; Bagley, S.; Bajcsy, P.; Bischof, J.; Brown, C. M.; Dauphin, A.; Dobbie, I. M.; Eriksson, J. E.; Faklaris, O. et al.; Fernandez-Rodriguez, J.; Ferrand, A.; Gelman, L.; Gheisari, A.; Hartmann, H.; Kukat, C.; Laude, A.; Mitkovski, M.; Munck, S.; North, A. J.; Rasse, T. M.; Resch-Genger, U.; Schuetz, L. C.; Seitz, A.; Strambio-De-Castillia, C.; Swedlow, J. R.; Alexopoulos, I.; Aumayr, K.; Avilov, S.; Bakker, G. J.; Bammann, R. R.; Bassi, A.; Beckert, H.; Beer, S.; Belyaev, Y.; Bierwagen, J.; Birngruber, K. A.; Bosch, M.; Breitlow, J.; Cameron, L. A.; Chalfoun, J.; Chambers, J. J.; Chen, C. L.; Conde-Sousa, E.; Corbett, A. D.; Cordelieres, F. P.; Nery, E. D.; Dietzel, R.; Eismann, F.; Fazeli, E.; Felscher, A.; Fried, H.; Gaudreault, N.; Goh, W. I.; Guilbert, T.; Hadleigh, R.; Hemmerich, P.; Holst, G. A.; Itano, M. S.; Jaffe, C. B.; Jambor, H. K.; Jarvis, S. C.; Keppler, A.; Kirchenbuechler, D.; Kirchner, M.; Kobayashi, N.; Krens, G.; Kunis, S.; Lacoste, J.; Marcello, M.; Martins, G. G.; Metcalf, D. J.; Mitchell, C. A.; Moore, J.; Mueller, T.; Nelson, M. S.; Ogg, S.; Onami, S.; Palmer, A. L.; Paul-Gilloteaux, P.; Pimentel, J. A.; Plantard, L.; Podder, S.; Rexhepaj, E.; Royon, A.; Saari, M. A.; Schapman, D.; Schoonderwoert, V.; Schroth-Diez, B.; Schwartz, S.; Shaw, M.; Spitaler, M.; Stoeckl, M. T.; Sudar, D.; Teillon, J.; Terjung, S.; Thuenauer, R.; Wilms, C. D.; Wright, G. D.; Nitschke, R.: QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy. Journal of Microscopy 284 (1), pp. 56 - 73 (2021)

Spieth, L.; Berghoff, S. A.; Stumpf, S. K.; Winchenbach, J.; Michaelis, T.; Watanabe, T.; Gerndt, N.; Düking, T.; Hofer, S.; Ruhwedel, T. et al.; Shaib, A. H.; Willig, K. I.; Kronenberg, K.; Karst, U.; Frahm, J.; Rhee, J. S.; Minguet, S.; Möbius, W.; Kruse, N.; von der Brelie, C.; Michels, P.; Stadelmann, C.; Hülper, P.; Saher, G.: Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neuro-Oncology Advances 3 (1), vdab140 (2021)

Kuljis, D. A.; Micheva, K. D.; Ray, A.; Wegner, W.; Bowman, R.; Madison, D. V.; Willig, K. I.; Barth, A. L.: Gephyrin-lacking PV synapses on neocortical pyramidal neurons. International Journal of Molecular Sciences 22 (18), 10032 (2021)

Khan, A.; Ramos Gomes, F.; Markus, M. A.; Mietsch, M.; Hinkel, R.; Alves, F.: Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy. Biomedical Optics Express (2021)

Gettings, S. M.; Maxeiner, S.; Tzika, M.; Cobain, M. R.D.; Ruf, I.; Benseler, F.; Brose, N.; Krasteva-Christ, G.; Vande Velde, G.; Schönberger, M. et al.; Althaus, M.: Two Functional Epithelial Sodium Channel Isoforms Are Present in Rodents despite Pronounced Evolutionary Pseudogenization and Exon Fusion. Molecular Biology and Evolution 38 (12), pp. 5704 - 5725 (2021)

Götze, T.; Soto-Bernardini, M. C.; Zhang, M.; Mießner, H.; Linhoff, L.; Brzózka, M. M.; Velanac, V.; Dullin, C.; Ramos Gomes, F.; Peng, M. et al.; Husseini, H.; Schifferdecker, E.; Fledrich, R.; Sereda, M. W.; Willig, K.; Alves, F.; Rossner, M. J.; Nave, K.-A.; Zhang, W.; Schwab, M. H.: Hyperactivity is a Core Endophenotype of Elevated Neuregulin-1 Signaling in Embryonic Glutamatergic Networks. SCHIZOPHRENIA BULLETIN 47 (5), pp. 1409 - 1420 (2021)

Deutsch, N.R.; Worthmann, H.; Steixner-Kumar, A. A.; Schuppner, R.; Grosse, G.M.; Pan, H.; Gabriel, M.M.; Hasse, I.; van Gemmeren, T.; Lichtinghagen, R. et al.; Ehrenreich, H.; Weissenborn, K.: Autoantibodies against the NMDAR subunit NR1 are associated with neuropsychiatric outcome after ischemic stroke. Brain, Behavior, and Immunity 96, pp. 73 - 79 (2021)

Wilke, J. B. H.; Hindermann, M.; Berghoff, S. A.; Zihsler, S.; Arinrad, S.; Ronnenberg, A.; Barnkothe, N.; Steixner-Kumar, A. A.; Röglin, S.; Stöcker, W. et al.; Hollmann, M.; Nave, K.; Lühder, F.; Ehrenreich, H.: Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis. Molecular Psychiatry 26, pp. 7746 - 7759 (2021)

Oliveira, L. M. A.; Gasser, T.; Edwards, R.; Zweckstetter, M.; Melki, R.; Stefanis, L.; Lashuel, H. A.; Sulzer, D.; Vekrellis, K.; Halliday, G. M. et al.; Tomlinson, J. J.; Schlossmacher, M.; Jensen, P. H.; Schulze-Hentrich, J.; Riess, O.; Hirst, W.D.; El-Agnaf, O.; Mollenhauer, B.; Lansbury, P.; Outeiro, T. F.: Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)

Wilke, J. B. H.; Hindermann, M.; Moussavi, A.; Butt, U. J.; Dadarwal, R.; Berghoff, S. A.; Sarcheshmeh, A. K.; Ronnenberg, A.; Zihsler, S.; Arinrad, S. et al.; Hardeland, R.; Seidel, J.; Lühder, F.; Nave, K.-A.; Boretius, S.; Ehrenreich, H.: Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis. Acta Neuropathologica Communications 9, 121 (2021)