Publikationen

Sasmita, A. O.; Depp, C.; Nazarenko, T.; Sun, T.; Siems, S. B.; Ong, E. C.; Nkeh, Y. B.; Böhler, C.; Yu, X.; Bues, B. et al.; Evangelista, L.; Mao, S.; Morgado, B.; Wu, Z.; Ruhwedel, T.; Subramanian, S.; Börensen, F.; Overhoff, K.; Spieth, L.; Berghoff, S. A.; Sadleir, K. R.; Vassar, R.; Eggert, S.; Goebbels, S.; Saito, T.; Saido, T.; Saher, G.; Möbius, W.; Castelo-Branco, G.; Klafki, H.-W.; Wirths, O.; Wiltfang, J.; Jäkel, S.; Yan, R.; Nave, K.-A.: Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice. Nature Neuroscience 27, S. 1668 - 1674 (2024)

Späte, E.; Zhou, B.; Sun, T.; Kusch, K.; Asadollahi, E.; Siems, S. B.; Depp, C.; Werner, H. B.; Saher, G.; Hirrlinger, J. et al.; Möbius, W.; Nave, K.-A.; Göbbels, S.: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia 72 (8), S. 1374 - 1391 (2024)

Krauter, D.; Stausberg, D.; Hartmann, T. J.; Volkmann, S.; Kungl, T.; Rasche, D. A.; Saher, G.; Fledrich, R.; Stassart, R.M.; Nave, K.-A. et al.; Göbbels, S.; Ewers, D.; Sereda, M. W.: Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases. Embo Molecular Medicine 16, S. 616 - 640 (2024)

Depp, C.; Sun, T.; Sasmita, A. O.; Spieth, L.; Berghoff, S. A.; Nazarenko, T.; Overhoff, K.; Steixner-Kumar, A. A.; Subramanian, S.; Arinrad, S. et al.; Ruhwedel, T.; Möbius, W.; Göbbels, S.; Saher, G.; Werner, H. B.; Damkou, A.; Zampar, S.; Wirths, O.; Thalmann, M.; Simons, M.; Saito, T.; Saido, T.; Krueger-Burg, D.; Kawaguchi, R.; Willem, M.; Haass, C.; Geschwind, D.; Ehrenreich, H.; Stassart, R. M.; Nave, K.-A.: Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. Nature 618, S. 349 - 357 (2023)

Gargareta, V.-I.; Reuschenbach, J.; Siems, S. B.; Sun, T.; Piepkorn, L.; Mangana, C.; Späte, E.; Goebbels, S.; Huitinga, I.; Möbius, W. et al.; Nave, K.-A.; Jahn, O.; Werner, H. B.: Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. eLife 11, e77019 (2022)

Bullock, G.; Johnson, G. S.; Mhlanga-Mutangadura, T.; Petesch, S. C.; Thompson, S.; Goebbels, S.; Katz, M. L.: Lysosomal storage disease associated with a CNP sequence variant in Dalmatian dogs. Gene 830, 146513 (2022)

Mukherjee, C.; Kling, T.; Russo, B.; Miebach, K.; Kess, E.; Schifferer, M.; Pedro, L. D.; Weikert, U.; Fard, M. K.; Kannaiyan, N. et al.; Rossner, M.; Aicher, M.-L.; Goebbels, S.; Nave, K.-A.; Krämer-Albers, E.-M.; Schneider, A.; Simons, M.: Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain. Cell Metabolism 32 (2), S. 259 - 272.e10 (2020)

Luo, L.; Ambrozkiewicz, M.; Benseler, F.; Chen, C.; Dumontier, E.; Falkner, S.; Furlanis, E.; Gomez, A. M.; Hoshina, N.; Huang, W.-H. et al.; Hutchison, M. A.; Itoh-Maruoka, Y.; Lavery, L. A.; Li, W.; Maruo, T.; Motohashi, J.; Pai, E. L.-L.; Pelkey, K. A.; Pereira, A.; Philips, T.; Sinclair, J. L.; Stogsdill, J. A.; Traunmüller, L.; Wang, J.; Wortel, J.; You, W.; Abumaria, N.; Beier, K. T.; Brose, N.; Burgess, H. A.; Cepko, C. L.; Cloutier, J.-F.; Eroglu, C.; Goebbels, S.; Kaeser, P. S.; Kay, J. N.; Lu, W.; Luo, L.; Mandai, K.; McBain, C. J.; Nave, K.-A.; Prado, M. A.M.; Prado, V. F.; Rothstein, J.; Rubenstein, J. L.R.; Saher, G.; Sakimura, K.; Sanes, J. R.; Scheiffele, P.; Takai, Y.; Umemori, H.; Verhage, M.; Yuzaki, M.; Zoghbi, H. Y.; Kawabe, H.; Craig, A. M.: Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors. Neuron 106 (1), S. 37 - 65.e5 (2020)

Hahn, M. A.; Jin, S.-G.; Li, A. X.; Liu, J.; Huang, Z.; Wu, X.; Kim, B.-W.; Johnson, J.; Bilbao, A.-D. V.; Tao, S. et al.; Yim, J. A.; Fong, Y.; Goebbels, S.; Schwab, M. H.; Lu, Q.; Pfeifer, G. P.: Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation. Science Advances 5 (10), aax0080 (2019)

Leitzen, E.; Raddatz, B. B.; Jin, W.; Goebbels, S.; Nave, K.-A.; Baumgärtner, W.; Hansmann, F.: Virus-triggered spinal cord demyelination is followed by a peripheral neuropathy resembling features of Guillain-Barré Syndrome. Scientific Reports 9, 4588 (2019)

Pieper, A.; Rudolph, S.; Wieser, G. L.; Götze, T.; Mießner, H.; Yonemasu, T.; Yan, K.; Tzvetanova, I.; Duverge Castillo, B.; Bode, U. et al.; Bormuth, I.; Wadiche, J. I.; Schwab, M. H.; Goebbels, S.: NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum. Scientific Reports 9, 1448 (2019)

Cathomas, F.; Azzinnari, D.; Bergamini, G.; Sigrist, H.; Buerge, M.; Hoop, V.; Wicki, B.; Goetze, L.; Soares, S.; Kukelova, D. et al.; Seifritz, E.; Goebbels, S.; Nave, K.-A.; Ghandour, S.; Seoighe, C.; Hildebrandt, T.; Leparc, G.; Klein, H.; Stupka, E.; Hengerer, B.; Pryce, C. R.: Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice. Genes, Brain and Behavior 18 (1), e12475 (2019)

Jin, W.; Leitzen, E.; Goebbels, S.; Nave, K.-A.; Baumgärtner, W.; Hansmann, F.: Comparison of Theiler’s Murine Encephalomyelitis Virus Induced Spinal Cord and Peripheral Nerve Lesions Following Intracerebral and Intraspinal Infection. International Journal of Molecular Sciences 20 (20), 5134 (2019)

Katz, E.; Stoler, O.; Scheller, A.; Khrapunsky, Y.; Goebbels, S.; Kirchhoff, F.; Gutnick, M. J.; Wolf, F.; Fleidervish, I. A.: Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America 38 (29), S. 6586 - 6596 (2018)

Janova, H.; Arinrad, S.; Balmuth, E.; Mitjans, M.; Hertel, J.; Habes, M.; Bittner, R. A.; Pan, H.; Goebbels, S.; Begemann, M. et al.; Gerwig, U. C.; Langner, S.; Werner, H. B.; Kittel-Schneider, S.; Homuth, G.; Davatzikos, C.; Völzke, H.; West, B. L.; Reif, A.; Grabe, H. J.; Boretius, S.; Ehrenreich, H.; Nave, K.-A.: Microglia ablation alleviates myelin-associated catatonic signs in mice. The Journal of Clinical Investigation 128 (2), S. 734 - 745 (2018)

Tognatta, R.; Sun, W.; Goebbels, S.; Nave, K.-A.; Nishiyama, A.; Schoch, S.; Dimou, L.; Dietrich, D.: Transient Cnp expression by early progenitors causes cre-lox-based reporter lines to map profoundly different fates. Glia 65 (2), S. 342 - 359 (2017)

Goebbels, S.; Wieser, G. L.; Pieper, A.; Spitzer, S.; Weege, B.; Yan, K.; Edgar, J. M.; Yagensky, O.; Wichert, S. P.; Agarwal, A. et al.; Karram, K.; Renier, N.; Tessier-Lavigne, M.; Rossner, M. J.; Káradóttir, R. T.; Nave, K.-A.: A neuronal PI(3,4,5)P₃-dependent program of oligodendrocyte precursor recruitment and myelination. Nature Neuroscience 20 (1), S. 10 - 15 (2017)

Hassouna, I.; Ott, C.; Wüstefeld, L.; Offen, N.; Neher, R. A.; Mitkovski, M.; Winkler, D.; Sperling, S.; Fries, L.; Goebbels, S. et al.; Vreja, I. C.; Hagemeyer, N.; Dittrich, M.; Rossetti, M. F.; Kröhnert, K.; Hannke, K.; Boretius, S.; Zeug, A.; Höschen, C.; Dandekar, T.; Dere, E.; Neher, E.; Rizzoli, S. O.; Nave, K.-A.; Sirén, A.-L.; Ehrenreich, H.: Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus. Molecular Psychiatry 21 (12), S. 1752 - 1767 (2016)

Poggi, G.; Boretius, S.; Möbius, W.; Moschny, N.; Baudewig, J.; Ruhwedel, T.; Hassouna, I.; Wieser, G. L.; Werner, H. B.; Goebbels, S. et al.; Nave, K.-A.; Ehrenreich, H.: Cortical network dysfunction caused by a subtle defect of myelination. Glia 64 (11), S. 2025 - 2040 (2016)

Vingill, S.; Brockelt, D.; Lancelin, C.; Tatenhorst, L.; Dontcheva, G.; Preisinger, C.; Schwedhelm-Domeyer, N.; Joseph, S.; Mitkovski, M.; Goebbels, S. et al.; Nave, K.-A.; Schulz, J. B.; Marquardt, T.; Lingor, P.; Stegmüller, J.: Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice. EMBO Journal 35 (18), S. 2008 - 2025 (2016)