Publikationen

Markusson, S.; Raasakka, A.; Schröder, M.; Sograte-Idrissi, S.; Rahimi, A.M.; Asadpour, O.; Körner, H.; Lodygin, D.; Eichel-Vogel, M. A.; Chowdhury, R. et al.; Sutinen, A.; Muruganandam, G.; Iyer, M.; Cooper, M.H.; Weigel, M.K.; Ambiel, N.; Werner, H. B.; Zuchero, J.B.; Opazo, F.; Kursula, P.: Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies. Journal of Neurochemistry 169 (1), e16274 (2025)

Siems, S. B.; Gargareta, V.-I.; Schadt, L. C.; Daguano Gastaldi, V.; Jung, R. B.; Piepkorn, L.; Casaccia, P.; Sun, T.; Jahn, O.; Werner, H. B.: Developmental maturation and regional heterogeneity but no sexual dimorphism of the murine CNS myelin proteome. Glia 73 (1), S. 38 - 56 (2025)

Garg, V.; André, S.; Heyer, L.; Kracht, G.; Ruhwedel, T.; Scholz, P.; Ischebeck, T.; Werner, H. B.; Dullin, C.; Engelmann, J. et al.; Möbius, W.; Göpfert, M. C.; Dosch, R.; Geurten, B. R. H.: Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia. Open Biology 14 (11), 240100 (2024)

Gargareta, V.-I.; Berghoff, S. A.; Krauter, D.; Hümmert, S.; Marshall‐Phelps, K. L. H.; Möbius, W.; Nave, K.-A.; Fledrich, R.; Werner, H. B.; Eichel-Vogel, M. A.: Myelinated peripheral axons are more vulnerable to mechanical trauma in a model of enlarged axonal diameters. Glia 72 (9), S. 1572 - 1589 (2024)

Späte, E.; Zhou, B.; Sun, T.; Kusch, K.; Asadollahi, E.; Siems, S. B.; Depp, C.; Werner, H. B.; Saher, G.; Hirrlinger, J. et al.; Möbius, W.; Nave, K.-A.; Göbbels, S.: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia 72 (8), S. 1374 - 1391 (2024)

Looser, Z.J.; Faik, Z.; Ravotto, L.; Zanker, H.S.; Jung, R. B.; Werner, H. B.; Ruhwedel, T.; Möbius, W.; Bergles, D.E.; Barros, L.F. et al.; Nave, K.-A.; Weber, B.; Saab, A.S.: Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health. Nature Neuroscience 27, S. 433 - 448 (2024)

Depp, C.; Sun, T.; Sasmita, A. O.; Spieth, L.; Berghoff, S. A.; Nazarenko, T.; Overhoff, K.; Steixner-Kumar, A. A.; Subramanian, S.; Arinrad, S. et al.; Ruhwedel, T.; Möbius, W.; Göbbels, S.; Saher, G.; Werner, H. B.; Damkou, A.; Zampar, S.; Wirths, O.; Thalmann, M.; Simons, M.; Saito, T.; Saido, T.; Krueger-Burg, D.; Kawaguchi, R.; Willem, M.; Haass, C.; Geschwind, D.; Ehrenreich, H.; Stassart, R. M.; Nave, K.-A.: Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. Nature 618, S. 349 - 357 (2023)

Krämer-Albers, E.-M.; Werner, H. B.: Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles. Nature Reviews Neuroscience 24, S. 474 - 486 (2023)

Arinrad, S.; Depp, C.; Siems, S. B.; Sasmita, A. O.; Eichel, M. A.; Ronnenberg, A.; Hammerschmidt, K.; Lüders, K. A.; Werner, H. B.; Ehrenreich, H. et al.; Nave, K.-A.: Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity. eLife 12, e70792 (2023)

Martens, A.-K.; Erwig, M. S.; Patzig, J.; Fledrich, R.; Füchtbauer, E.; Werner, H. B.: Targeted inactivation of the Septin2 and Septin9 genes in myelinating Schwann cells of mice. Cytoskeleton 80 (7-8), S. 290 - 302 (2023)

Paes de Faria, J.; Vale-Silva, R. S.; Fässler, R.; Werner, H. B.; Relvas, J. B.: Pinch2 regulates myelination in the mouse central nervous system. Development 149 (13), dev200597 (2022)

Gargareta, V.-I.; Reuschenbach, J.; Siems, S. B.; Sun, T.; Piepkorn, L.; Mangana, C.; Späte, E.; Goebbels, S.; Huitinga, I.; Möbius, W. et al.; Nave, K.-A.; Jahn, O.; Werner, H. B.: Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. eLife 11, e77019 (2022)

Buscham, T. J.; Eichel-Vogel, M. A.; Steyer, A. M.; Jahn, O.; Strenzke, N.; Dardawal, R.; Memhave, T. R.; Siems, S. B.; Müller, C.; Meschkat, M. et al.; Sun, T.; Ruhwedel, T.; Möbius, W.; Krämer-Albers, E.-M.; Boretius, S.; Nave, K.-A.; Werner, H. B.: Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5. eLife 11, e75523 (2022)

Siems, S. B.; Jahn, O.; Hoodless, L. J.; Jung, R. B.; Hesse, D.; Möbius, W.; Czopka, T.; Werner, H. B.: Proteome Profile of Myelin in the Zebrafish Brain. Frontiers in Cell and Developmental Biology 9, 640169 (2021)

Trevisiol, A.; Kusch, K.; Steyer, A. M.; Gregor, I.; Nardis, C.; Winkler, U.; Köhler, S.; Restrepo, A.; Möbius, W.; Werner, H. B. et al.; Nave, K.-A.; Hirrlinger, J.: Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia. PLoS Biology 18 (11), e3000943 (2020)

Jahn, O.; Siems, S. B.; Kusch, K.; Hesse, D.; Jung, R. B.; Liepold, T.; Uecker, M.; Sun, T.; Werner, H. B.: The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay. Frontiers in Cellular Neuroscience 14, 249 (2020)

Steyer, A. M.; Ruhwedel, T.; Nardis, C.; Werner, H. B.; Nave, K.-A.; Möbius, W.: Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy. Journal of Structural Biology 210 (2), 107492 (2020)

Wakhloo, D.; Scharkowski, F.; Curto, Y.; Butt, U. J.; Bansal, V.; Steixner-Kumar, A. A.; Wüstefeld, L.; Rajput, A.; Arinrad, S.; Zillmann, M. R. et al.; Seelbach, A.; Hassouna, I.; Schneider, K.; Qadir Ibrahim, A.; Werner, H. B.; Werner, H. B.; Martens, H.; Miskowiak, K.; Wojcik, S. M.; Wojcik, S. M.; Bonn, S.; Nacher, J.; Nave, K. A.; Ehrenreich, H.: Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin. Nature Communications 11, 1313 (2020)

Siems, S. B.; Jahn, O.; Eichel, M. A.; Kannaiyan, N.; Wu, L. M. N.; Sherman, D. L.; Kusch, K.; Hesse, D.; Jung, R. B.; Fledrich, R. et al.; Sereda, M. W.; Rossner, M. J.; Brophy, P. J.; Werner, H. B.: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. eLife 9, e51406 (2020)

Buscham, T. J.; Eichel, M. A.; Siems, S. B.; Werner, H. B.: Turning to myelin turnover. Neural Regeneration Research 14 (12), S. 2063 - 2066 (2019)