Selected Publications

Hümmert, S.; de Faria, J. P.; Jahn, O.; Bilgin, E.; Łukasik, N.; Rao, C.; Mitkovski, M.; Benseler, F.; Brose, N.; Siems, S. B. et al.; Goebbels, S.; Möbius, W.; Ewers, H.; Relvas, J. B.; Werner, H. B.: CDC42-Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity. Glia 74 (3), e70134 (2026)

Siems, S. B.; Gargareta, V.-I.; Schadt, L. C.; Daguano Gastaldi, V.; Jung, R. B.; Piepkorn, L.; Casaccia, P.; Sun, T.; Jahn, O.; Werner, H. B.: Developmental maturation and regional heterogeneity but no sexual dimorphism of the murine CNS myelin proteome. Glia 73 (1), pp. 38 - 56 (2025)

Krämer-Albers, E.-M.; Werner, H. B.: Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles. Nature Reviews Neuroscience 24, pp. 474 - 486 (2023)

Gargareta, V.-I.; Reuschenbach, J.; Siems, S. B.; Sun, T.; Piepkorn, L.; Mangana, C.; Späte, E.; Goebbels, S.; Huitinga, I.; Möbius, W. et al.; Nave, K.-A.; Jahn, O.; Werner, H. B.: Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. eLife 11, e77019 (2022)

Buscham, T. J.; Eichel-Vogel, M. A.; Steyer, A. M.; Jahn, O.; Strenzke, N.; Dardawal, R.; Memhave, T. R.; Siems, S. B.; Müller, C.; Meschkat, M. et al.; Sun, T.; Ruhwedel, T.; Möbius, W.; Krämer-Albers, E.-M.; Boretius, S.; Nave, K.-A.; Werner, H. B.: Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5. eLife 11, e75523 (2022)

Siems, S. B.; Jahn, O.; Hoodless, L. J.; Jung, R. B.; Hesse, D.; Möbius, W.; Czopka, T.; Werner, H. B.: Proteome Profile of Myelin in the Zebrafish Brain. Frontiers in Cell and Developmental Biology 9, 640169 (2021)

Nave, K.-A.; Werner, H. B.: Ensheathment and Myelination of Axons: Evolution of Glial Functions. Annual Review of Neuroscience 44, pp. 197 - 219 (2021)

Eichel, M. A.; Gargareta, V.-I.; D’Este, E.; Fledrich, R.; Kungl, T.; Buscham, T. J.; Lüders, K. A.; Miracle, C.; Jung, R. B.; Distler, U. et al.; Kusch, K.; Möbius, W.; Hülsmann, S.; Tenzer, S.; Nave, K.-A.; Werner, H. B.: CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves. Nature Communications 11 (1), 4514 (2020)

Jahn, O.; Siems, S. B.; Kusch, K.; Hesse, D.; Jung, R. B.; Liepold, T.; Uecker, M.; Sun, T.; Werner, H. B.: The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay. Frontiers in Cellular Neuroscience 14, 249 (2020)

Siems, S. B.; Jahn, O.; Eichel, M. A.; Kannaiyan, N.; Wu, L. M. N.; Sherman, D. L.; Kusch, K.; Hesse, D.; Jung, R. B.; Fledrich, R. et al.; Sereda, M. W.; Rossner, M. J.; Brophy, P. J.; Werner, H. B.: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. eLife 9, e51406 (2020)

Lüders, K. A.; Nessler, S.; Kusch, K.; Patzig, J.; Jung, R. B.; Möbius, W.; Nave, K.-A.; Werner, H. B.: Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons. Glia 67 (4), pp. 634 - 649 (2019)

Erwig, M. S.; Patzig, J.; Steyer, A. M.; Dibaj, P.; Heilmann, M.; Heilmann, I.; Jung, R. B.; Kusch, K.; Möbius, W.; Jahn, O. et al.; Nave, K.-A.; Werner, H. B.: Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin. eLife 8, e43888 (2019)

Weil, M.-T.; Heibeck, S.; Töpperwien, M.; tom Dieck, S.; Ruhwedel, T.; Salditt, T.; Rodicio, M. C.; Morgan, J. R.; Nave, K.-A.; Möbius, W. et al.; Werner, H. B.: Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia. The Journal of Neuroscience 38 (29), pp. 6586 - 6596 (2018)

Patzig, J.; Erwig, M. S.; Tenzer, S.; Kusch, K.; Dibaj, P.; Möbius, W.; Goebbels, S.; Schaeren-Wiemers, N.; Nave, K.-A.; Werner, H. B.: Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction. eLife 5, e17119 (2016)

Thakurela, S.; Garding, A.; Jung, R. B.; Müller, C.; Goebbels, S.; White, R.; Werner, H. B.; Tiwari, V. K.: The transcriptome of mouse central nervous system myelin. Scientific Reports 6, 25828 (2016)

Nave, K.-A.; Werner, H. B.: Myelination of the Nervous System: Mechanisms and Functions. Annual Review of Cell and Developmental Biology 30, pp. 503 - 533 (2014)

Monasterio-Schrader, P. d.; Patzig, J.; Möbius, W.; Barrette, B.; Wagner, T. L.; Kusch, K.; Edgar, J. M.; Brophy, P. J.; Werner, H. B.: Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. Glia 61 (11), pp. 1832 - 1847 (2013)

Itoh, T.; Erdmann, K. S.; Roux, A.; Habermann, B.; Werner, H. B.; De Camilli, P.: Dynamin and the Actin Cytoskeleton Cooperatively Regulate Plasma Membrane Invagination by BAR and F-BAR Proteins. Developmental Cell 9 (6), pp. 791 - 804 (2005)