Publications of M. Konrad
All genres
Journal Article (90)
21.
Journal Article
20 (4), pp. 533 - 540 (2013)
Free glycine accelerates the autoproteolytic activation of human asparaginase. Chemistry and Biology 22.
Journal Article
13 (8), pp. 1472 - 1475 (2013)
Micro-optical lens array for fluorescence detection in droplet-based microfluidics. Lab on a Chip 23.
Journal Article
162 (3), pp. 599 - 605 (2012)
Controlled enzyme-catalyzed degradation of polymeric capsules templated on CaCO3: Influence of the number of LbL layers, conditions of degradation, and disassembly of multicompartments. Journal of Controlled Release 24.
Journal Article
51 (34), pp. 6816 - 6826 (2012)
Structures of apo and product-bound human L-asparaginase: Insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry 25.
Journal Article
279 (11), pp. 1915 - 1928 (2012)
Balance of human choline kinase isoforms is critical for cell cycle regulation: Implications for the development of choline kinase-targeted cancer therapy. FEBS Journal 26.
Journal Article
7 (4), pp. 663 - 669 (2012)
Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line. ChemMedChem 27.
Journal Article
50 (14), pp. 2870 - 2880 (2011)
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry 28.
Journal Article
49 (44), pp. 8116 - 8120 (2010)
Enzyme reaction in the pores of CaCO3 particles upon ultrasound disruption of attached substrate-filled liposomes. Angewandte Chemie International Edition 29.
Journal Article
122 (44), pp. 8293 - 8297 (2010)
Enzymreaktion in den Poren von CaCO3-Partikeln mit angelagerten, mit Substrat gefüllten Liposomen. Angewandte Chemie 30.
Journal Article
5 (9), e12999 (2010)
Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms. PLoS ONE 31.
Journal Article
53 (15), pp. 5792 - 5800 (2010)
The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): Implications for the development of dCK-activated acyclic guanine analogues. Journal of Medicinal Chemistry 32.
Journal Article
49 (31), pp. 6784 - 6790 (2010)
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry 33.
Journal Article
48 (6), pp. 1256 - 1263 (2009)
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry 34.
Journal Article
17 (11), pp. 1946 - 1954 (2008)
Structural requirements for calmodulin binding to membrane-associated guanylate kinase homologs. Protein Science 35.
Journal Article
89 (7), pp. 1672 - 1679 (2008)
Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells. Journal of General Virology 36.
Journal Article
68 (6), pp. 1583 - 1594 (2008)
Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Molecular Microbiology 37.
Journal Article
378 (3), pp. 607 - 621 (2008)
Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology 38.
Journal Article
582 (5), pp. 720 - 724 (2008)
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters 39.
Journal Article
283 (4), pp. 1902 - 1910 (2008)
Ultra short yeast tropomyosins show novel myosin regulation. Journal of Biological Chemistry 40.
Journal Article
51 (14), pp. 4219 - 4225 (2008)
Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase. Journal of Medicinal Chemistry