Publikationen von Tiago F. Outeiro

López-León, M.; Outeiro, T. F.; Goya, R. G.: Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain. Ageing Research Reviews 40, S. 168 - 181 (2017)

Lázaro, D. F.; Castro Dias, M.; Carija, A.; Navarro, S.; Silva Madaleno, C.; Tenreiro, S.; Ventura, S.; Outeiro, T. F.: The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation. Acta Neuropathologica Communications 4, 128 (2016)

Miranda, H. V.; Gomes, M. A.; Branco-Santos, J.; Breda, C.; Lázaro, D. F.; Vaqueiro Lopes, L.; Herrera, F.; Giorgini, F.; Outeiro, T. F.: Glycation potentiates neurodegeneration in models of Huntington's disease. Scientific Reports 6, 36798 (2016)

Villar-Piqué, A.; Lopes da Fonseca, T.; Sant'Anna, R.; Szegö, É. M.; Fonseca-Ornelas, L.; Pinho, R.; Carija, A.; Gerhardt, E.; Masaracchia, C.; Gonzalez, E. A. et al.; Rossetti, G.; Carloni, P.; Fernández, C. O.; Foguel, D.; Milosevic, I.; Zweckstetter, M.; Ventura, S.; Outeiro, T. F.: Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 113 (42), S. E6506 - E6515 (2016)

Letra-Vilela, R.; Sánchez-Sánchez, A. M.; Rocha, A. M.; Martin, V.; Branco-Santos, J.; Puente-Moncada, N.; Santa-Marta, M.; Outeiro, T. F.; Antolín, I.; Rodriguez, C. et al.; Herrera, F.: Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin. Molecular and Cellular Endocrinology 434, S. 238 - 249 (2016)

Batalha, V. L.; Ferreira, D. G.; Coelho, J. E.; Valadas, J. S.; Gomes, R.; Temido-Ferreira, M.; Shmidt, T.; Baqi, Y.; Buée, L.; Müller, C. E. et al.; Hamdane, M.; Outeiro, T. F.; Bader, M.; Meijsing, S.; Sadri-Vakili, G.; Blum, D.; Lopes, L. V.: The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Scientific Reports 6, 31493 (2016)

Lopes da Fonseca, T.; Pinho, R.; Outeiro, T. F.: A familial ATP13A2 mutation enhances alpha-synuclein aggregation and promotes cell death. Human Molecular Genetics 25 (14), S. 2959 - 2971 (2016)

Kleinknecht, A.; Popova, B.; Lázaro, D. F.; Pinho, R.; Valerius, O.; Outeiro, T. F.; Braus, G. H.: C-terminal tyrosine residue modifications modulate the protective phosphorylation of Serine 129 of α-synuclein in a yeast model of Parkinson's disease. PLoS Genetics 12 (6), e1006098 (2016)

Miranda, H. V.; El-Agnaf, O. M. A.; Outeiro, T. F.: Glycation in Parkinson's disease and Alzheimer's disease. Movement Disorders 31 (6), S. 782 - 790 (2016)

Goncalves, S. A.; Macedo, D.; Raquel, H.; Simões, P. D.; Giorgini, F.; Ramalho, J. S.; Barral, D. C.; Moita, L. F.; Outeiro, T. F.: shRNA-based screen identifiers endocytic recycling pathway components that act as genetic modifiers of alpha-synuclein aggregation, secretion and toxicity. PLoS Genetics 12, e1005995 (2016)

Tenreiro, S.; Rosado-Ramos, R.; Gerhardt, E.; Favretto, F.; Magalhães, F.; Popova, B.; Becker, S.; Zweckstetter, M.; Braus, G. H.; Outeiro, T. F.: Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Human Molecular Genetics 25 (2), S. 275 - 290 (2016)

Oliveira, L. M. A.; Falomir, L. J.; Gralle Botelho, M.; Lin, K. H.; Wales, P.; Koch, J.; Gerhardt, E.; Taschenberger, H.; Outeiro, T. F.; Lingor, P. et al.; Schüle, B.; Arndt-Jovin, D. J.; Jovin, T. M.: Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells. Cell Death and Disease 6, e1994 (2015)

Del-Bel, E.; Bortolanza, M.; Do Nascimento, G.C.; Raisman-Vozari, R.; Dos Santos Pereira, M.; González-Lizárraga, F.; Parrales, V.; Michel, P.; Ploper, D.; Ávila, C.L. et al.; Socias, S.; Outeiro, T. F.; Chehin, R.: Doxycycline Therapeutic Approach in Parkinson’s Disease and L-DOPA-Induced Dyskinesia. In: Handbook of Neurotoxicity, S. 1539 - 1559 (Hg. Kostrzewa, R. M.). Springer, Cham (2022)

Szegõ, É. M.; Outeiro, T. F.; Kazantsev, A. G.: Sirtuins in brain and neurodegenerative disease. In: Introductory review on sirtuins in biology, aging, and aging disease, S. 175 - 195 (Hg. Guarente, L.) (2018)

Pavlou, M. A. S.; Outeiro, T. F.: Epigenetics in Parkinson's disease. In: Neuroepigenomics in aging and disease (Hg. Delgado Morales, R.) (2017)

Outeiro, T. F.; Brocardo, P. S.; Gelain, D. P.: Aging and neurodegeneration: From molecular mechanisms to therapeutic interventions. Journal of Neurochemistry 168 (8), S. 1421 - 1683 (2024)

Fernandes, J. B.; Baixinho, C.; Outeiro, T. F.; Godinho, C.: One health care in psychiatric and neurological diseases. Frontiers in Psychiatry 15, 1399709 (2024)

Fernandes, J. B.; Godinho, C.; Outeiro, T. F.; Baixinho, C. L.: Editorial: Personalized care in neurological diseases. Frontiers in Human Neuroscience 17, 1216902 (2023)

Fourcade, S.; Outeiro, T. F.; Pujol, A.: SIRT2 in age-related neurodegenerative disorders. Aging 10 (3), S. 295 - 296 (2018)

Brücke, C.; Al-Azzani, M.; Ramalingam, N.; Ramón, M.; Sousa, R. L.; Buratti, F.; Zech, M.; Sicking, K.; Amaral, L.; Gelpi, E. et al.; Chandran, A.; Agarwal, A.; Chaves, S. R.; Fernández, C. O.; Dettmer, U.; Lautenschläger, J.; Zweckstetter, M.; Fernandez Busnadiego, R.; Zimprich, A.; Outeiro, T. F.: A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features. medRxiv (2025)