Publikationen von M. Konrad
Alle Typen
Zeitschriftenartikel (90)
Zeitschriftenartikel
277 (6), S. 4159 - 4165 (2002)
Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains. Journal of Biological Chemistry
Zeitschriftenartikel
268, S. 1972 - 1981 (2001)
Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene. European Journal of Biochemistry
Zeitschriftenartikel
183, S. 4910 - 4913 (2001)
YLR 209 c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase. Journal of Bacteriology
Zeitschriftenartikel
40, S. 7334 - 7341 (2001)
Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequence. Biochemistry
Zeitschriftenartikel
267, S. 606 - 615 (2000)
Cloning of the guanylate kinase homologues AGK-1 and AGK-2 from Arabidopsis thaliana and characterization of AGK-1. European Journal of Biochemistry
Zeitschriftenartikel
156, S. 953 - 961 (2000)
Yeast GMP kinase mutants constitutively express AMP biosynthesis genes by phenocopying a hypoxanthine-guanine phosphoribosyltransferase defect. Genetics
Zeitschriftenartikel
39, S. 11913 - 11920 (2000)
Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modification. Biochemistry
Zeitschriftenartikel
304, S. 43 - 53 (2000)
Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. Journal of Molecular Biology
Zeitschriftenartikel
8, S. 629 - 642 (2000)
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. Structure
Zeitschriftenartikel
274, S. 35289 - 35292 (1999)
Modifying human thymidylate kinase to potentiate AZT activation. Journal of Biological Chemistry
Zeitschriftenartikel
274, S. 35337 - 35342 (1999)
Binding of nucleotides to guanylate kinase, p21ras, and nucleoside-diphosphate kinase studied by nano-electrospray mass spectrometry. Journal of Biological Chemistry
Zeitschriftenartikel
274, S. 20159 - 20164 (1999)
Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation. Journal of Biological Chemistry
Zeitschriftenartikel
252, S. 305 - 313 (1998)
Functional analysis of the guanylate kinase-like domain in the synapse-associated protein SAP97. European Journal of Biochemistry
Zeitschriftenartikel
37, S. 3677 - 3686 (1998)
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation. Biochemistry
Zeitschriftenartikel
95, S. 14045 - 14050 (1998)
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences USA
Zeitschriftenartikel
273, S. 5662 - 5670 (1998)
Transient kinetic studies on phosphoryl transfer reactions of human nucleoside diphosphate kinase. Journal of Biological Chemistry
Zeitschriftenartikel
3 (8), S. 922 - 924 (1997)
The bottleneck in AZT activation. Nature Medicine
Zeitschriftenartikel
272 (25), S. 15599 - 15602 (1997)
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding. Journal of Biological Chemistry
Zeitschriftenartikel
72 (2), S. TH387 - TH387 (1997)
Transient kinetic studies of phosphate-transfer reactions in human-beta nucleoside diphosphate kinase. Biophysical Journal
Zeitschriftenartikel
4, S. 601 - 604 (1997)
Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature Structural Biology