Publikationen von Tiago F. Outeiro

Brasil, A. A.; Magalhães, R. S. S.; De Carvalho, M. D. C.; Paiva, I.; Gerhardt, E.; Pereira, M. D.; Outeiro, T. F.; Eleutherio, E. C. A.: Implications of fALS mutations on Sod1 function and oligomerization in cell models. Molecular Neurobiology 55, S. 5269 - 5281 (2018)

Carmona-Gutierrez, D.; Bauer, M. A.; Zimmermann, A.; Aguilera, A.; Austriaco, N.; Ayscough, K.; Balzan, R.; Bar-Nun, S.; Barrientos, A.; Belenky, P. et al.; Blondel, M.; Braun, R. J.; Breitenbach, M.; Burhans, W. C.; Büttner, S.; Cavalieri, D.; Chang, M.; Cooper, K. F.; Côrte-Real, M.; Costa, V.; Cullin, C.; Dawes, I.; Dengjel, J.; Dickman, M. B.; Eisenberg, T.; Fahrenkrog, B.; Fasel, N.; Fröhlich, K.-U.; Gargouri, A.; Giannattasio, S.; Goffrini, P.; Gourlay, C. W.; Grant, C. M.; Greenwood, M. T.; Guaragnella, N.; Heger, T.; Heinisch, J.; Herker, E.; Herrmann, J. M.; Hofer, S.; Jiménez-Ruiz, A.; Jungwirth, H.; Kainz, K.; Kontoyiannis, D. P.; Ludovico, P.; Manon, S.; Martegani, E.; Mazzoni, C.; Megeney, L. A.; Meisinger, C.; Nielsen, J.; Nyström, T.; Osiewacz, H. D.; Outeiro, T. F.; Park, H.-O.; Pendl, T.; Petranovic, D.; Picot, S.; Polčic, P.; Powers, T.; Ramsdale, M.; Rinnerthaler, M.; Rockenfeller, P.; Ruckenstuhl, C.; Schaffrath, R.; Segovia, M.; Severin, F. F.; Sharon, A.; Sigrist, S. J.; Sommer-Ruck, C.; Sousa, M. J.; Thevelein, J. M.; Thevissen, K.; Titorenko, V.; Toledano, M. B.; Tuite, M.; Vögtle, F.-N.; Westermann, B.; Winderickx, J.; Wissing, S.; Wölfl, S.; Zhang, Z. J.; Zhao, R. Y.; Zhou, B.; Galluzzi, L.; Kroemer, G.; Madeo, F.: Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 5 (1), S. 4 - 31 (2018)

König, A.; Miranda, H. V.; Outeiro, T. F.: Alpha-synuclein glycation and the action of anti-diabetic agents in Parkinson's disease. Journal of Parkinson's Disease: JPD 8 (1), S. 33 - 43 (2018)

Paiva, I.; Jain, G.; Lázaro, D. F.; Gotovac Jercic, K.; Hentrich, T.; Kerimoglu, C.; Pinho, R.; Szego, È. M.; Burkhardt, S.; Capece, V. et al.; Halder, R.; Islam, R.; Xylaki, M.; Caldi Gomes, L. A.; Roser, A.-E.; Lingor, P.; Schulze-Hentrich, J. M.; Borovecki, F.; Fischer, A.; Outeiro, T. F.: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function. Neurobiology of Disease 119, S. 121 - 135 (2018)

Pujols, J.; Peña-Díaz, S.; Lázaro, D. F.; Peccati, F.; Pinheiro, F.; González, D.; Carija, A.; Navarro, S.; Conde-Giménez, M.; García, J. et al.; Guardiola, S.; Giralt, E.; Salvatella, X.; Sancho, J.; Sodupe, M.; Outeiro, T. F.; Dalfó, E.; Ventura, S.: Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America 115 (41), S. 10481 - 10486 (2018)

Bozek, T.; Blazekovic, A.; Nikolac Perkovic, M.; Gotovac Jercic, K.; Sustar, A.; Smircic-Duvnjak, L.; Outeiro, T. F.; Pivac, N.; Borovecki, F.: The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus. Diabetology & Metabolic Syndrome 9, 97 (2017)

Ferreira, D. G.; Temido-Ferreira, M.; Miranda, H. V.; Batalha, V. L.; Coelho, J. E.; Szegö, É. M.; Marques-Morgado, I.; Vaz, S. H.; Rhee, J. S.; Schmitz, M. et al.; Zerr, I.; Lopes, L. V.; Outeiro, T. F.: Alpha-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience 20 (11), S. 1569 - 1579 (2017)

Miranda, H. V.; Cássio, R.; Correia-Guedes, L.; Gomes, M. A.; Chegão, A.; Miranda, E.; Soares, T.; Coelho, M.; Rosa, M. M.; Ferreira, J. J. et al.; Outeiro, T. F.: Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease. Scientific Reports 7, 13713 (2017)

Guedes, L. C.; Reimão, S.; Paulino, P.; Nunes, R. G.; Bouça-Machado, R.; Abreu, D.; Gonçalves, N.; Soares, T.; Fabbri, M.; Godinho, C. et al.; Lobo, P. P.; Neutel, D.; Quadri, M.; Coelho, M.; Rosa, M. M.; Campos, J.; Outeiro, T. F.; Sampaio, C.; Bonifati, V.; Ferreira, J. J.: Neuromelanin magnetic resonance imaging of the Substantia Nigra in LRRK2-related Parkinson's disease. Movement Disorders 32 (9), S. 1331 - 1333 (2017)

Moreira, S.; Fonseca, I.; Nunes, M. J.; Rosa, A.; Lemos, L.; Rodrigues, E.; Neves Carvalho, A.; Outeiro, T. F.; Pereira Rodrigues, C. M.; Gama, M. J. et al.; Castro-Caldas, M.: Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease. Experimental Neurology 295, S. 77 - 87 (2017)

Szegö, É. M.; Gerhardt, E.; Outeiro, T. F.: Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway. Neurobiology of Aging 56, S. 7 - 16 (2017)

Pardo, J.; Abba , M. C.; Lacunza, E.; Ogundele, O. M.; Paiva, I.; Morel, G. R.; Outeiro, T. F.; Goya, R. G.: IGF-I gene therapy in aging rats modulates hippocampal genes relevant to memory function. Journals of Gerontology: Series A, Biological Sciences and Medical Sciences 73 (4), S. 459 - 467 (2017)

Paiva, I.; Pinho, R.; Pavlou, M. A.; Hennion, M.; Wales, P.; Schütz, A.-L.; Rajput, A.; Szegö, É. M.; Kerimoglu, C.; Gerhardt, E. et al.; Rego, A. C.; Fischer, A.; Bonn, S.; Outeiro, T. F.: Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. Human Molecular Genetics 26 (12), S. 2231 - 2246 (2017)

Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. et al.; Becker, D.: Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25), S. E4971 - E4977 (2017)

Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J. et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25), S. E4971 - E4977 (2017)

Miranda, H. V.; Szegö, É. M.; Oliveira, L. M. A.; Breda, C.; Darendelioglu, E.; Oliveira, R. M. d.; Ferreira, D. G.; Gomes, M. A.; Rott, R.; Oliveira, M. et al.; Munari, F.; Enguita, F. J.; Simões, T.; Rodrigues, E. F.; Heinrich, M.; Martins, I. C.; Zamolo, I.; Riess, O.; Cordeiro, C.; Ponces-Freire, A.; Lashuel, H. A.; Santos, N. C.; Lopes, L. V.; Xiang, W.; Jovin, T. M.; Penque, D.; Engelender, S.; Zweckstetter, M.; Klucken, J.; Giorgini, F.; Quintas, A.; Outeiro, T. F.: Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies. Brain 140, S. 1399 - 1419 (2017)

Pavlou, M. A. S.; Pinho, R.; Paiva, I.; Outeiro, T. F.: The yin and yang of α-synuclein-associated epigenetics in Parkinson's disease. Brain 140, S. 878 - 886 (2017)

Machado de Oliveira, R.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegö, É. M.; Martinho, R.; Munari, F.; Lázaro, D. F.; Moniot, S.; Guerreiro, P. et al.; Fonseca, L.; Marijanovic, Z.; Antas, P.; Gerhardt, E.; Enguita, F. J.; Fauvet, B.; Penque, D.; Pais, T. F.; Tong, Q.; Becker, S.; Kügler, S.; Lashuel, H. A.; Steegborn, C.; Zweckstetter, M.; Outeiro, T. F.: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 15 (3), e1002601 (2017)

Menges, S.; Minakaki, G.; Schaefer, P. M.; Meixner, H.; Prots, I.; Schlötzer-Schrehardt, U.; Friedland, K.; Winner, B.; Outeiro, T. F.; Winklhofer, K. F. et al.; von Arnim, C. A. F.; Xiang, W.; Winkler, J.; Klucken, J.: Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Scientific Reports 7, 42942 (2017)

Branco-Santos, J.; Herrera, F.; Poças, G. M.; Pires-Afonso, Y.; Giorgini, F.; Domingos, P. M.; Outeiro, T. F.: Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity. Human Molecular Genetics 26 (19), S. 3763 - 3775 (2017)