Publikationen von R. Lührmann
Alle Typen
Zeitschriftenartikel (189)
1.
Zeitschriftenartikel
12 (3), e759 (2022)
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells. Clinical and Translational Medicine 2.
Zeitschriftenartikel
596 (7871), S. 296 - 300 (2021)
Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature 3.
Zeitschriftenartikel
49 (10), S. 5845 - 5866 (2021)
SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes. Nucleic Acids Research 4.
Zeitschriftenartikel
371 (6526), S. 305 - 309 (2021)
Structure of a transcribing RNA polymerase II–U1 snRNP complex. Science 5.
Zeitschriftenartikel
370 (6523), eabc3753 (2020)
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science 6.
Zeitschriftenartikel
80 (1), S. 127 - 139.e6 (2020)
Structural insights into the roles of metazoan-specific splicing factors in the human step 1 spliceosome. Molecular Cell 7.
Zeitschriftenartikel
583 (7815), S. 310 - 313 (2020)
Molecular architecture of the human 17S U2 snRNP. Nature 8.
Zeitschriftenartikel
77 (6), S. 1322 - 1339.e11 (2020)
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. Molecular Cell 9.
Zeitschriftenartikel
26 (2), S. vii - viii (2020)
Kiyoshi Nagai (1949-2019). RNA 10.
Zeitschriftenartikel
11 (11), a032417 (2019)
Structural insights into nuclear pre-mRNA splicing in higher eukaryotes. Cold Spring Harbor Perspectives in Biology 11.
Zeitschriftenartikel
105 (3), S. 573 - 587 (2019)
Pathogenic abnormal splicing due to intronic deletions that induce biophysical space constraint for spliceosome assembly. American Journal of Human Genetics 12.
Zeitschriftenartikel
10 (1), 3639 (2019)
Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns. Nature Communications 13.
Zeitschriftenartikel
46 (22), S. 12126 - 12138 (2018)
Multiple RNA-RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome. Nucleic Acids Research 14.
Zeitschriftenartikel
9, 4234 (2018)
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 15.
Zeitschriftenartikel
46 (7), S. 3774 - 3790 (2018)
The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation. Nucleic Acids Research 16.
Zeitschriftenartikel
70 (2), S. 265 - 273 (2018)
Structural basis of splicing modulation by antitumor macrolide compounds. Molecular Cell 17.
Zeitschriftenartikel
69 (6), S. 979 - 992 (2018)
Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 18.
Zeitschriftenartikel
172 (3), S. 454 - 464, e1-e5 (2018)
Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 19.
Zeitschriftenartikel
23 (12), S. 1770 - 1779 (2017)
Yeast Prp2 liberates the 5' splice site and the branch site adenosine for catalysis of pre-mRNA splicing. RNA 20.
Zeitschriftenartikel
31 (23-24), S. 2416 - 2429 (2017)
The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development