Publikationen von Simone Eggert

Tyan, S.-H.; Shih, A. Y.-J.; Walsh, J. J.; Maruyama, H.; Sarsoza, F.; Ku, L.; Eggert, S.; Hof, P. R.; Koo, E. H.; Dickstein, D. L.: Amyloid precursor protein (APP) regulates synaptic structure and function. Molecular and Cellular Neuroscience 51 (1-2), S. 43 - 52 (2012)

Baumkötter, F.; Wagner, K.; Eggert, S.; Wild, K.; Kins, S.: Structural aspects and physiological consequences of APP/APLP trans-dimerization. Experimental Brain Research 217, S. 389 - 395 (2012)

Isbert, S.; Wagner, K.; Eggert, S.; Schweitzer, A.; Multhaup, G.; Weggen, S.; Kins, S.; Pietrzik, C. U.: APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms. Cellular and Molecular Life Sciences 69, S. 1353 - 1375 (2012)

Midthune, B.; Tyan, S.-H.; Walsh, J. J.; Sarsoza, F.; Eggert, S.; Hof, P. R.; Dickstein, D. L.; Koo, E. H.: Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. Molecular and Cellular Neuroscience 49 (4), S. 448 - 455 (2012)

Kukar, T. L.; Ladd, T. B.; Robertson, P.; Pintchovski, S. A.; Moore, B.; Bann, M. A.; Ren, Z.; Jansen-West, K.; Malphrus, K.; Eggert, S. et al.; Maruyama, H.; Cottrell, B. A.; Das, P.; Basi, G. S.; Koo, E. H.; Golde, T. E.: Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length. Journal of Biological Chemistry 286 (46), S. 39804 - 39812 (2011)

Eggert, S.; Midthune, B.; Cottrell, B.; Koo, E. H.: Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-β Protein Production. Journal of Biological Chemistry 284 (42), S. 28943 - 28952 (2009)

Kuan, Y.-H.; Gruebl, T.; Soba, P.; Eggert, S.; Nesic, I.; Back, S.; Kirsch, J.; Beyreuther, K.; Kins, S.: PAT1a Modulates Intracellular Transport and Processing of Amyloid Precursor Protein (APP), APLP1, and APLP2. Journal of Biological Chemistry 281 (52), S. 40114 - 40123 (2006)

Soba, P.; Eggert, S.; Wagner, K.; Zentgraf, H.; Siehl, K.; Kreger, S.; Löwer, A.; Langer, A.; Merdes, G.; Paro, R. et al.; Masters, C. L.; Müller, U.; Kins, S.; Beyreuther, K.: Homo- and heterodimerization of APP family members promotes intercellular adhesion. The EMBO Journal 24, S. 3624 - 3634 (2005)

Eggert, S.; Paliga, K.; Soba, P.; Evin, G.; Masters, C. L.; Weidemann, A.; Beyreuther, K.: The Proteolytic Processing of the Amyloid Precursor Protein Gene Family Members APLP-1 and APLP-2 Involves α-, β-, γ-, and ϵ-Like Cleavages. Journal of Biological Chemistry 279 (18), S. 18146 - 18156 (2004)

Walsh, D. M.; Fadeeva, J. V.; LaVoie, M. J.; Paliga, K.; Eggert, S.; Kimberly, W. T.; Wasco, W.; Selkoe, D. J.: γ-Secretase Cleavage and Binding to FE65 Regulate the Nuclear Translocation of the Intracellular C-Terminal Domain (ICD) of the APP Family of Proteins. Biochemistry 42 (22), S. 6664 - 6673 (2003)

Weidemann, A.; Eggert, S.; Reinhard, F. B. M.; Vogel, M.; Paliga, K.; Baier, G.; Masters, C. L.; Beyreuther, K.; Evin, G.: A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing. Biochemistry 41 (8), S. 2825 - 2835 (2002)

Sasmita, A. O.; Depp, C.; Nazarenko, T.; Sun, T.; Siems, S. B.; Yu, X.; Böhler, C.; Ong, E. C.; Bues, B.; Evangelista, L. et al.; Morgado, B.; Wu, Z.; Ruhwedel, T.; Subramanian, S.; Börensen, F.; Overhoff, K.; Spieth, L.; Berghoff, S. A.; Sadleir, K. R.; Vassar, R.; Eggert, S.; Goebbels, S.; Saito, T.; Saido, T.; Möbius, W.; Castelo-Branco, G.; Klafki, H.-W.; Wirths, O.; Wiltfang, J.; Jäkel, S.; Yan, R.; Nave, K.-A.: Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease. bioRxiv (2023)