Publikationen von Henning Urlaub

Zhang, Z.; Kumar, V.; Dybkov, O.; Will, C. L.; Zhong, J.; Ludwig, S. E. J.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature 630, S. 1012 - 1019 (2024)

Harasimov, K.; Gorry, R. L.; Welp, L. M.; Penir, S. M.; Horokhovskyi, Y.; Cheng, S.; Takaoka, K.; Stützer, A.; Frombach, A.-S.; Taylor Tavares, A. L. et al.; Raabe, M.; Haag, S.; Saha, D.; Grewe, K.; Schipper, V.; Rizzoli, S. O.; Urlaub, H.; Liepe, J.; Schuh, M.: The maintenance of oocytes in the mammalian ovary involves extreme protein longevity. Nature Cell Biology 26, S. 1124 - 1138 (2024)

Velychko, T.; Mohammad, E.; Ferrer-Vicens, I.; Parfentev, I.; Werner, M.; Studniarek, C.; Schwalb, B.; Urlaub, H.; Murphy, S.; Cramer, P. et al.; Lidschreiber, M.: CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release. Molecular Cell 84 (12), S. 2287 - 2303.e10 (2024)

James, C.; Möller, U.; Spillner, C.; König, S.; Dybkov, O.; Urlaub, H.; Lenz, C.; Kehlenbach, R. H.: Phosphorylation of ELYS promotes its interaction with VAPB at decondensing chromosomes during mitosis. EMBO Reports 25 (5), S. 2391 - 2417 (2024)

Tarău, D.; Grünberger, F.; Pilsl, M.; Reichelt, R.; Heiß, F.; König, S.; Urlaub, H.; Hausner, W.; Engel, C.; Grohmann, D.: Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Research 52 (10), S. 6017 - 6035 (2024)

Fianu, I.; Ochmann, M.; Walshe, J. L.; Dybkov, O.; Cruz, J. N.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-dependent RNA polymerase II termination. Nature 629, S. 219 - 227 (2024)

Corcoran, S. R.; Phelan, J. D.; Choi, J.; Shevchenko, G.; Fenner, R. E.; Yu, X.; Scheich, S.; Hsiao, T.; Morris, V. M.; Papachristou, E. K. et al.; Kishore, K.; D'Santos, C. S.; Ji, Y.; Pittaluga, S.; Wright, G. W.; Urlaub, H.; Pan, K.-T.; Oellerich, T.; Muppidi, J.; Hodson, D. J.; Staudt, L. M.: Molecular Determinants of Sensitivity to Polatuzumab Vedotin in Diffuse Large B Cell Lymphoma. Cancer Discovery 14 (9), S. 1653 - 1674 (2024)

Zhuang, X.; Woods, J.; Ji, Y.; Scheich, S.; Mo, F.; Rajagopalan, S.; Coulibaly, Z. A.; Voss, M.; Urlaub, H.; Staudt, L. M. et al.; Pan, K.-T.; Long, E. O.: Functional genomics identifies N-acetyllactosamine extension of complex N-glycans as a mechanism to evade lysis by natural killer cells. Cell Reports 43 (4), 114105 (2024)

Atkinson, R.; Georgiou, M.; Yang, C.; Szymanska, K.; Lahat, A.; Vasconcelos, E.J.R.; Ji, Y.; Moya Molina, M.; Collin, J.; Queen, R. et al.; Dorgau, B.; Watson, A.; Kurzawa-Akanbi, M.; Laws, R.; Saxena, A.; Shyan Beh, C.; Siachisumo, C.; Goertler, F.; Karwatka, M.; Davey, T.; Inglehearn, C.F.; McKibbin, M.; Lührmann, R.; Steel, D.H.; Elliott, D.J.; Armstrong, L.; Urlaub, H.; Ali, R.R.; Grellscheid, S.-N.; Johnson, C.A.; Mozaffari-Jovin, S.; Lako, M.: PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects. Nature Communications 15, 3138 (2024)

Siraj, A.; Bouwmeester, R.; Declercq, A.; Welp, L.; Chernev, A.; Wulf, A.; Urlaub, H.; Martens, L.; Degroeve, S.; Kohlbacher, O. et al.; Sachsenberg, T.: Intensity and retention time prediction improves the rescoring of protein‐nucleic acid cross‐links. Proteomics 24 (8), 2300144 (2024)

Xu, M.; Ito-Kureha, T.; Kang, H.-S.; Chernev, A.; Raj, T.; Hoefig, K. P.; Hohn, C.; Giesert, F.; Wang, Y.; Pan, W. et al.; Ziętara, N.; Straub, T.; Feederle, R.; Daniel, C.; Adler, B.; König, J.; Feske, S.; Tsokos, G. C.; Wurst, W.; Urlaub, H.; Sattler, M.; Kisielow, J.; Wulczyn, F. G.; Łyszkiewicz, M.; Heissmeyer, V.: The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression. Nature Communications 15, 2194 (2024)

Kokic, G.; Yakoub, G.; van den Heuvel, D.; Wondergem, A. P.; van der Meer, P. J.; van der Weegen, Y.; Chernev, A.; Fianu, I.; Fokkens, T. J.; Lorenz, S. et al.; Urlaub, H.; Cramer, P.; Luijsterburg, M. S.: Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nature Structural & Molecular Biology 31, S. 536 - 547 (2024)

Kanwal, N.; Krogh, N.; Memet, I.; Lemus-Diaz, N.; Thomé, C. C.; Welp, L. M.; Mizi, A.; Hackert, P.; Papantonis, A.; Urlaub, H. et al.; Nielsen, H.; Bohnsack, K. E.; Bohnsack, M. T.: GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners. Nucleic Acids Research 52 (4), S. 1953 - 1974 (2024)

Zhang, Z.; Kumar, V.; Dybkov, O.; Will, C. L.; Urlaub, H.; Stark, H.; Lührmann, R.: Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. The EMBO Journal 43, S. 1065 - 1088 (2024)

Phelan, J. D.; Scheich, S.; Choi, J.; Wright, G. W.; Häupl, B.; Young, R. M.; Rieke, S. A.; Pape, M.; Ji, Y.; Urlaub, H. et al.; Bolomsky, A.; Doebele, C.; Zindel, A.; Wotapek, T.; Kasbekar, M.; Collinge, B.; Huang, D. W.; Coulibaly, Z. A.; Morris, V. M.; Zhuang, X.; Enssle, J. C.; Yu, X.; Xu, W.; Yang, Y.; Zhao, H.; Wang, Z.; Tran, A. D.; Shoemaker, C. J.; Shevchenko, G.; Hodson, D. J.; Shaffer, A. L.; Staudt, L. M.; Oellerich, T.: Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy. Cancer Cell 42 (2), S. 238 - 252.e9 (2024)

Düring, J.; Wolter, M.; Toplak, J. J.; Torres, C.; Dybkov, O.; Fokkens, T. J.; Bohnsack, K. E.; Urlaub, H.; Steinchen, W.; Dienemann, C. et al.; Lorenz, S.: Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Nature Structural & Molecular Biology 31, S. 364 - 377 (2024)

Soh, W. T.; Roetschke, H. P.; Cormican, J. A.; Teo, B.F.; Chiam, N. C.; Raabe, M.; Pflanz, R.; Henneberg, F.; Becker, S.; Chari, A. et al.; Liu, H.; Urlaub, H.; Liepe, J.; Mishto, M.: Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications 15 (1), 1147 (2024)

Cepeda, A. P.; Ninov, M.; Neef, J.; Parfentev, I.; Kusch, K.; Reisinger, E.; Jahn, R.; Moser, T.; Urlaub, H.: Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair Cells. Molecular & Cellular Proteomics 23 (2), 100704 (2024)

Altas, B.; Rhee, H. J.; Ju, A.; Solis, H. C.; Karaca, S.; Winchenbach, J.; Kaplan-Arabaci, O.; Schwark, M.; Ambrozkiewicz, M.; Lee, C. et al.; Spieth, L.; Wieser, G. L.; Chaugule, V. K.; Majoul, I.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Koganezawa, N.; Hanamura, K.; Rotin, D.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Poulopoulos, A.; Urlaub, H.; Jahn, O.; Saher, G.; Brose, N.; Rhee, J.; Kawabe, H.: Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 223 (1), e201902050 (2024)

Binotti, B.; Ninov, M.; Cepeda, A. P.; Ganzella, M.; Matti, U.; Riedel, D.; Urlaub, H.; Sambandan, S.; Jahn, R.: ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals. Autophagy 20 (4), S. 883 - 901 (2024)