Publikationen von R. Luehrmann

Makarova, O.; Makarov, E. M.; Liu, S.; Vornlocher, H. P.; Luehrmann, R.: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6 center dot U5 tri-snRNP formation and pre-mRNA splicing. EMBO Journal 21 (5), S. 1148 - 1157 (2002)

Huber, J.; Dickmanns, A.; Luehrmann, R.: The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro. Journal of Cell Biology 156 (3), S. 467 - 479 (2002)

Urlaub, H.; Hartmuth, K.; Luehrmann, R.: A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles. Methods 26 (2), S. 170 - 181 (2002)

Mougin, A.; Gottschalk, A.; Fabrizio, P.; Luehrmann, R.; Branlant, C.: Direct probing of RNA structure and RNA-protein interactions in purifies HeLa cells and yeast spliceosomal U4/U6.U5 tri-snRNP particles. Journal of Biological Chemistry 317 (5), S. 631 - 649 (2002)

Achsel, T.; Stark, H.; Luehrmann, R.: The Sm domain is an ancient RNA binding motif with oligo[U] specificity. Proceedings of the National Academy of Sciences USA 98, S. 3685 - 3689 (2001)

Brahms, H.; Meheus, L.; De Brabandere, V.; Fischer, U.; Luehrmann, R.: Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA 7, S. 1531 - 1542 (2001)

Gottschalk, A.; Kastner, B.; Luehrmann, R.; Fabrizio, P.: The yeast U5 snRNP co-isolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7, S. 1554 - 1566 (2001)

Gottschalk, A.; Neubauer, G.; Luehrmann, R.; Fabrizio, P.: A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly. Molecular and Cellular Biology 21, S. 3037 - 3046 (2001)

Kues, T.; Dickmanns, A.; Luehrmann, R.; Peters, R.; Kubitscheck, U.: High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking. Proceedings of the National Academy of Sciences USA 98, S. 12021 - 12026 (2001)

Makarova, O.; Makarov, E. M.; Luehrmann, R.: The 65-kD and 110-kD SR-related proteins of the human [U4/U6.U5] tri-snRNP are essential for association of the tri-snRNP with pre-spliceosomes. EMBO Journal 10, S. 2553 - 2563 (2001)

Pillai, R. S.; Will, C. L.; Luehrmann, R.; Schuemperli, D.; Mueller, B.: Purified U7 snRNPs lack the Sm proteins D 1 and D 2 but contain Lsm 10, a new 14-kDa Sm D 1-like protein. EMBO Journal 20, S. 5470 - 5479 (2001)

Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: Arrangement of RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, S. 539 - 542 (2001)

Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: The 3-D arrangement for RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, S. 539 - 542 (2001)

Urlaub, H.; Raker, V. A.; Kostka, S.; Luehrmann, R.: Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. EMBO Journal 20, S. 187 - 196 (2001)

Vidovic, I.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Ficner, R.: Crystal structure of the spliceosomal 15.5 kD protein bound to a U4 snRNA fragment. Molecular Cell 6, S. 1331 - 1342 (2001)

Will, C. L.; Luehrmann, R.: Spliceosomal U snRNP biogenesis, structure and function. Current Opinion in Cell Biology 13, S. 290 - 301 (2001)

Will, C. L.; Luehrmann, R.: RNP remodeling with DExH/D Boxes. Science 291, S. 1916 - 1917 (2001)

Will, C. L.; Schneider, C.; MacMilan, A. M.; Neubauer, G.; Wilm, M.; Luehrmann, R.; Query, C. C.: A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. EMBO Journal 20, S. 4536 - 4546 (2001)

Brahms, H.; Raymackers, J.; Union, A.; de Keyser, F.; Meheus, L.; Luehrmann, R.: The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D 1 and D 3 contain symmetrical dimethylarginines which form a major B-cell epitope for anti-Sm autoantibodies. Journal of Biological Chemistry 275, S. 17122 - 17129 (2000)

Makarov, E. M.; Makarova, O.; Achsel, T.; Luehrmann, R.: The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. Journal of Molecular Biology 298, S. 567 - 575 (2000)