Publications of M. Zweckstetter

Karpinar, P.; Gajula Balija, M. B.; Kügler, S.; Opazo, F.; Rezaei-Ghaleh, N.; Wender, N.; Kim, H. Y.; Taschenberger, G.; Falkenburger, B. H.; Heise, H. et al.; Kumar, A.; Riedel, D.; Fichtner, L.; Voigt, A.; Braus, G. H.; Giller, K.; Becker, S.; Herzig, A.; Baldus, M.; Jäckle, H.; Eimer, S.; Schulz, J. B.; Griesinger, C.; Zweckstetter, M.: Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), pp. 3256 - 3268 (2009)

Mukrasch, M.; Bibow, S.; Korukottu, J.; Jeganathan, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)

Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nehmat-Gorgani, M.: Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), pp. 28 - 36 (2009)

Coudevylle, N.; Montaville, P.; Leonov, M.; Zweckstetter, M.; Becker, S.: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), pp. 35918 - 35928 (2008)

Rumpel, S.; Lakshmi, R.; Becker, S.; Zweckstetter, M.: Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), pp. 2015 - 2019 (2008)

Soragni, A.; Zambelli, B.; Mukrasch, M.; Biernat, J.; Jeganathan, S.; Griesinger, C.; Ciurli, S.; Mandelkow, E.; Zweckstetter, M.: Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), pp. 10841 - 10851 (2008)

Bayrhuber, M.; Meins, T.; Habeck, M.; Becker, S.; Giller, K.; Villinger, S.; Vonrhein, C.; Griesinger, C.; Zweckstetter, M.; Zeth, K.: Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), pp. 15370 - 15375 (2008)

El-Turk, F.; Cascella, M.; Ouertatami-Sakonhi, H.; Lakshmi, R. N.; Leng, L.; Bucala, R.; Zweckstetter, M.; Rothlisberger, U.; Lashuel, H. A.: The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), pp. 10740 - 10756 (2008)

Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), pp. 11801 - 11812 (2008)

Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), pp. 5046 - 5048 (2008)

Korukottu, J.; Schneider, R.; Vijayan, V.; Lange, A.; Pongs, O.; Becker, S.; Baldus, M.; Zweckstetter, M.: High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)

Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, pp. 16895 - 16905 (2008)

Sevvana, M.; Vijayan, V.; Zweckstetter, M.; Reinelt, S.; Madden, D. R.; Herbst-Irmer, R.; Sheldrick, G. M.; Bott, M.; Griesinger, C.; Becker, S.: A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), pp. 512 - 523 (2008)

Zweckstetter, M.: NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), pp. 679 - 690 (2008)

Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), pp. 1025 - 1034 (2008)

Rumpel, S.; Becker, S.; Zweckstetter, M.: High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), pp. 1 - 13 (2008)

Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), pp. 708 - 722 (2007)

Mukrasch, M.; von Bergen, M.; Biernat, J.; Fischer, D.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), pp. 12230 - 12239 (2007)

Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), pp. 3032 - 3033 (2007)

Fischer, D.; Mukrasch, M.; von Bergen, M.; Klos-Witkowska, A.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), pp. 2574 - 2582 (2007)