Publications of Stefan Jakobs

Preminger, N.; Zucker, B.; Hassdenteufel, S.; Stephan, T.; Jakobs, S.; Kozlov, M. M.; Schuldiner, M.: A data-driven model for mitochondrial inner membrane remodeling as a driving force of organelle shaping. Journal of Cell Science (2025)

Lange, F.; Ratz, M.; Dohrke, J.-N.; Le Vasseur, M.; Wenzel, D.; Ilgen, P.; Riedel, D.; Jakobs, S.: In situ architecture of the human prohibitin complex. Nature Cell Biology 27, pp. 633 - 640 (2025)

Saller, B. S.; Wöhrle, S.; Fischer, L.; Dufossez, C.; Ingerl, I. L.; Kessler, S.; Mateo-Tortola, M.; Gorka, O.; Lange, F.; Cheng, Y. et al.; Neuwirt, E.; Marada, A.; Koentges, C.; Urban, C.; Aktories, P.; Reuther, P.; Giese, S.; Kirschnek, S.; Mayer, C.; Pilic, J.; Falquez-Medina, H.; Oelgeklaus, A.; Deepagan, V. G.; Shojaee, F.; Zimmermann, J. A.; Weber, D.; Tai, Y.-H.; Crois, A.; Ciminski, K.; Peyronnet, R.; Brandenburg, K. S.; Wu, G.; Baumeister, R.; Heimbucher, T.; Rizzi, M.; Riedel, D.; Helmstädter, M.; Buescher, J.; Neumann, K.; Misgeld, T.; Kerschensteiner, M.; Walentek, P.; Kreutz, C.; Maurer, U.; Rambold, A. S.; Vince, J. E.; Edlich, F.; Malli, R.; Häcker, G.; Kierdorf, K.; Meisinger, C.; Köttgen, A.; Jakobs, S.; Weber, A. N.R.; Schwemmle, M.; Groß, C. J.; Groß, O.: Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity 58 (1), pp. 90 - 107.e11 (2025)

Elancheliyan, P.; Maruszczak, K. K.; Serwa, R. A.; Stephan, T.; Gulgec, A. S.; Borrero-Landazabal, M. A.; Ngati, S.; Gosk, A.; Jakobs, S.; Wasilewski, M. et al.; Chacinska, A.: OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase. Cell Reports 43 (12), 115038 (2024)

Scholz, J.; Stephan, T.; Pérez, A. G.; Csiszár, A.; Hersch, N.; Fischer, L. S.; Brühmann, S.; Körber, S.; Litschko, C.; Mijanovic, L. et al.; Kaufmann, T.; Lange, F.; Springer, R.; Pich, A.; Jakobs, S.; Peckham, M.; Tarantola, M.; Grashoff, C.; Merkel, R.; Faix, J.: Decisive role of mDia-family formins in cell cortex function of highly adherent cells. Science Advances 10 (44), eadp5929 (2024)

Sahl, S. J.; Matthias, J.; Inamdar, K.; Weber, M.; Khan, T. A.; Brüser, C.; Jakobs, S.; Becker, S.; Griesinger, C.; Broichhagen, J. et al.; Hell, S. W.: Direct optical measurement of intramolecular distances with angstrom precision. Science 386 (6718), pp. 180 - 187 (2024)

Reshetniak, S.; Bogaciu, C. A.; Bonn, S.; Brose, N.; Cooper, B. H.; D'Este, E.; Fauth, M.; Fernández‐Busnadiego, R.; Fiosins, M.; Fischer, A. et al.; Georgiev, S. V.; Jakobs, S.; Klumpp, S.; Köster, S.; Lange, F.; Lipstein, N.; Macarrón‐Palacios, V.; Milovanovic, D.; Moser, T.; Müller, M.; Opazo, F.; Outeiro, T. F.; Pape, C.; Priesemann, V.; Rehling, P.; Salditt, T.; Schlüter, O.; Simeth, N.; Steinem, C.; Tchumatchenko, T.; Tetzlaff, C.; Tirard, M.; Urlaub, H.; Wichmann, C.; Wolf, F.; Rizzoli, S. O.: The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function. The Journal of Physiology (2024)

Naas, J.; Nies, G.; Li, H.; Stoldt, S.; Schmitzer, B.; Jakobs, S.; Munk, A.: MultiMatch: geometry-informed colocalization in multi-color super-resolution microscopy. Communications Biology 7, 1139 (2024)

Stephan, T.; Ilgen, P.; Jakobs, S.: Visualizing mitochondrial dynamics at the nanoscale. Light: Science & Applications 13, 244 (2024)

Aich, A.; Boshnakovska, A.; Witte, S.; Gall, T.; Unthan-Fechner, K.; Yousefi, R.; Chowdhury, A.; Dahal, D.; Methi, A.; Kaufmann, S. et al.; Silbern, I.; Prochazka, J.; Nichtova, Z.; Palkova, M.; Raishbrook, M.; Koubkova, G.; Sedlacek, R.; Tröder, S.E.; Zevnik, B.; Riedel, D.; Michanski, S.; Möbius, W.; Ströbel, P.; Lüchtenborg, C.; Giavalisco, P.; Urlaub, H.; Fischer, A.; Brügger, B.; Jakobs, S.; Rehling, P.: Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nature Communications 15, 6914 (2024)

Saleem, H. N.; Ignatyeva, N.; Stuut, C.; Jakobs, S.; Habeck, M.; Ebert, A.: 3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models. Cells 13 (11), p. 923 (2024)

Chen, J.; Stephan, T.; Gaedke, F.; Liu, T.; Li, Y.; Schauss, A.; Chen, P.; Wulff, V.; Jakobs, S.; Jüngst, C. et al.; Chen, Z.: An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells. PNAS 121 (19), e2317703121 (2024)

Schweighofer, S. V.; Jans, D. C.; Keller-Findeisen, J.; Folmeg, A.; Ilgen, P.; Bates, M.; Jakobs, S.: Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria. Cell Death & Differentiation 31, pp. 469 - 478 (2024)

Hintze, A.; Lange, F.; Steyer, A. M.; Anstatt, J.; Möbius, W.; Jakobs, S.; Wichmann, C.: Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus. iScience 27 (1), 108700 (2024)

Stephan, T.; Stoldt, S.; Barbot, M.; Carney, T. D.; Lange, F.; Bates, M.; Bou Dib, P.; Inamdar, K.; Shcherbata, H. R.; Meinecke, M. et al.; Riedel, D.; Dennerlein, S.; Rehling, P.; Jakobs, S.: Drosophila MIC10b can polymerize into cristae-shaping filaments. Life science alliance 7 (4), e202302177 (2024)

Kim, D.; Stoldt, S.; Weber, M.; Jakobs, S.; Belov, V. N.; Hell, S. W.: A Bright Surprise: Live-Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag. Chemistry Methods 3 (9), e202200076 (2023)

Michanski, S.; Henneck, T.; Mukhopadhyay, M.; Steyer, A. M.; Gonzalez, P.A.; Grewe, K.; Ilgen, P.; Gültas, M.; Fornasiero, E.F.; Jakobs, S. et al.; Möbius, W.; Vogl, C.; Pangršič, T.; Rizzoli, S.O.; Wichmann, C.: Age-dependent structural reorganization of utricular ribbon synapses. Frontiers in Cell and Developmental Biology 11, 1178992 (2023)

Ebrahimi, V.; Stephan, T.; Kim, J.; Carravilla, P.; Eggeling, C.; Jakobs, S.; Han, K. Y.: Deep learning enables fast, gentle STED microscopy. Communications Biology 6 (1), 674 (2023)

Liu, T.; Stephan, T.; Chen, P.; Keller-Findeisen, J.; Chen, J.; Riedel, D.; Yang, Z.; Jakobs, S.; Chen, Z.: Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain. Proceedings of the National Academy of Sciences of the United States of America 119 (52), e2215799119 (2022)

Stejerean-Todoran, I.; Zimmermann, K.; Gibhardt, C. S.; Vultur, A.; Ickes, C.; Shannan, B.; Rio, Z. B. d.; Wölling, A.; Cappello, S.; Sung, H.-M. et al.; Shumanska, M.; Zhang, X.; Nanadikar, M.; Latif, M. U.; Wittek, A.; Lange, F.; Waters, A.; Brafford, P.; Wilting, J.; Urlaub, H.; Katschinski, D. M.; Rehling, P.; Lenz, C.; Jakobs, S.; Ellenrieder, V.; Roesch, A.; Schön, M. P.; Herlyn, M.; Stanisz, H.; Bogeski, I.: MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Reports 23, e54746 (2022)