Mary Osborn

Selected publications

Weber, K. and Osborn, M.
The reliability of molecular weight determination by dodecylsulfate polyacrylamide gel electrophoresis.
J. Biol. Chem. 244:4406-4412 (1969).

Osborn, M. and Weber, K.
SV40 gene A function and maintenance of transformation.
J. Virol. 15:636-644 (1975).

Osborn, M. and Weber, K.
Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane.
Proc. Natl. Acad. Sci. USA 73:867-870 (1976).

Osborn, M., Franke, W.W. and Weber, K.
Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (PtK2) by immunofluorescence microscopy.
Proc. Natl. Acad. Sci. USA 74:2490-2494 (1977).

Osborn, M., Born, T., Koitzsch, H.J. and Weber, K.
Stereo immunofluorescence microscopy. I. Three-dimensional arrangement of microfilaments, microtubules and tonofilaments.
Cell 14:477-488 (1978).

Osborn, M., Webster, R.E. and Weber, K.
Individual microtubules viewed by immunofluorescence and electron microscopy in the same PtK2 cell.
J. Cell Biol. 77:R27-R34 (1978).

Osborn, M. and Weber, K.
Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology.
Lab. Invest. 48:372-394 (1983).

Domagala, W., Lasota, J., Chosia, M., Szadowska, A., Weber, K. and Osborn, M.
Diagnosis of major tumor categories in fine needle aspirates is more accurate when light microscopy is combined with intermediate filament typing: a study of 403 cases.
Cancer 63:504-517 (1989).

Kallajoki, M., Weber, K. and Osborn, M.
A 210 kD nuclear matrix protein is a functional part of the mitotic spindle; a microinjection study using SPN monoclonal antibodies.
EMBO J. 10:3351-3362 (1991).

Harborth, J., Weber, K., and Osborn, M.
Epitope mapping and direct visualization of the parallel, in-register arrangement of the double-stranded coiled-coil in the NuMA protein.
EMBO J. 14:2447-2460 (1995).

Harborth, J., Wang, J., Gueth-Hallonet, C., Weber, K. and Osborn, M.
Self assemby of NuMA: multiarm oligomers as structural units of a nuclear lattice.
EMBO J. 18:1689-1700 (1999).

Gruber, J., Lampe, T., Osborn, M. and Weber K.
RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome.
J. Cell Sci. 118:689-696 (2005).

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