Zeitschriftenartikel (133)
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biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes. Proceedings of the National Academy of Sciences of the United States of America 113 (19), S. E2564 - E2569 (2016)
52.
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Molecular architecture of the human U4/U6.U5 tri-snRNP. Science 351 (6280), S. 1416 - 1420 (2016)
53.
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Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy. Microscopy 65 (1), S. 23 - 34 (2016)
54.
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Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 4, e11349 (2015)
55.
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ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods 12 (9), S. 859 - 865 (2015)
56.
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GraDeR: Membrane protein complex preparation for single-particle cryo-EM. Structure 23 (9), S. 1769 - 1775 (2015)
57.
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Expression of enterovirus 71 virus-like particles in transgenic enoki (Flammulina velutipes). Applied Microbiology and Biotechnology 99 (16), S. 6765 - 6774 (2015)
58.
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Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), S. 1079 - 1089 (2015)
59.
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RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex. Proceedings of the National Academy of Sciences of the United States of America 112 (17), S. 5272 - 5279 (2015)
60.
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Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 520 (7548), S. 567 - 570 (2015)
61.
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Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly. Molecular Cell 56 (2), S. 246 - 260 (2014)
62.
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Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit. Structure 22 (6), S. 923 - 930 (2014)
63.
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Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), S. 1390 - 1396 (2013)
64.
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Structural determinants and mechanism of mammalian CRM1 allostery. Structure 21 (8), S. 1350 - 1360 (2013)
65.
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Electron microscopy structure of human APC/C-CDH1-EMI1 reveals multimodal mechanism of E3 ligase shutdown. Nature Structural and Molecular Biology 20 (7), S. 827 - 835 (2013)
66.
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Structural basis of assembly chaperone- mediated snRNP formation. Molecular Cell 49 (4), S. 692 - 703 (2013)
67.
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Automated correlation of single particle tilt pairs for Random Conical Tilt and Orthogonal Tilt Reconstructions. Journal of Structural Biology 181 (2), S. 149 - 154 (2013)
68.
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Structural basis for cooperativity of CRM1 export complex formation. Proceedings of the National Academy of Sciences of the United States of America 110 (3), S. 960 - 965 (2013)
69.
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Novel insights into the architecture and protein interaction network of yeast eIF3. RNA 18 (12), S. 2306 - 2319 (2012)
70.
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APC15 mediates CDC20 autoubiquitylation by APC/C-MCC and disassembly of the mitotic checkpoint complex. Nature Structural and Molecular Biology 19 (11), S. 1116 - 1123 (2012)
71.
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Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy. Journal of Biological Chemistry 286 (44), S. 38748 - 38756 (2011)
72.
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Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Molecular and Cellular Proteomics 10 (11), S. 10.1074/mcp.M110.005371-1 - 10.1074/mcp.M110.005371–16 (2011)
73.
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Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. Nature Structural and Molecular Biology 18, S. 6 - 13 (2010)
74.
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3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core. Molecular Cell 40 (6), S. 927 - 938 (2010)
75.
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Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA 16 (12), S. 2384 - 2403 (2010)
76.
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The MIS12 complex is a protein interaction hub for outer kinetochore assembly. Journal of Cell Biology 190 (5), S. 835 - 852 (2010)
77.
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An approach for de novo structure determination of dynamic molecular assemblies by electron cryomicroscopy. Structure 18 (6), S. 667 - 676 (2010)
78.
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Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 328 (5978), S. 593 - 599 (2010)
79.
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Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy. Nature 466 (7304), S. 329 - 333 (2010)
80.
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Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion. Molecular and Cellular Proteomics 9, S. 1729 - 1741 (2010)
81.
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Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: Influence of macromolecular structure on gene vector particle properties and transfection efficiency. Biomacromolecules 11 (1), S. 39 - 50 (2010)
82.
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Reconstitution of both steps of S. cerevisiae splicing with purified spliceosomal components. Nature Structural and Molecular Biology 16 (12), S. 1237 - 1243 (2009)
83.
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Self-assembly of ternary insulin−polyethylenimine (PEI)−DNA nanoparticles for enhanced gene delivery and expression in alveolar epithelial cells. Biomacromolecules 10 (10), S. 2912 - 2920 (2009)
84.
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Exon, intron and splice site locations in the spliceosomal B complex. EMBO Journal 28, S. 2283 - 2292 (2009)
85.
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Self-assembly of a nanoscale DNA box with a controllable lid. Nature 459 (7243), S. 73 - 76 (2009)
86.
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Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo. EMBO Journal 28 (6), S. 766 - 778 (2009)
87.
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Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 323 (5920), S. 1477 - 1481 (2009)
88.
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The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Molecular Cell 36 (4), S. 593 - 608 (2009)
89.
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Structural mapping of spliceosomes by electron microscopy. Current Opinion in Structural Biology 19, S. 96 - 102 (2009)
90.
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DNA translocation activity of the multifunctional replication protein ORF904 from the archaeal plasmid pRN1. Nucleic Acids Research 37 (20), S. 6831 - 6848 (2009)
91.
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Parallel, distributed and GPU computing technologies in single-particle electron microscopy. Acta Crystallographica D 65 (7), S. 659 - 671 (2009)
92.
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Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopy. RNA 14, S. 2528 - 2537 (2008)
93.
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Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nature Structural and Molecular Biology 15 (11), S. 1206 - 1212 (2008)
94.
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An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Cell 135 (3), S. 497 - 509 (2008)
95.
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GraFix: sample preparation for single-particle electron cryomicroscopy. Nature Methods 5 (1), S. 53 - 55 (2008)
96.
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Structural insight into filament formation by mammalian septins. Nature 449 (7160), S. 311 - 315 (2007)
97.
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Improved identification of enriched peptide–RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Research 35 (15), e95 (2007)
98.
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Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 26 (6), S. 1737 - 1748 (2007)
99.
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Spontaneous reverse movement of mRNA-bound tRNA through the ribosome. Nature Structural Molecular Biology 14, S. 318 - 324 (2007)
100.
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Organization of Core Spliceosomal Components U5 snRNA Loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as Revealed by Electron Cryomicroscopy. Molecular Cell 24 (2), S. 267 - 278 (2006)