Zeitschriftenartikel (129)

51.
Zeitschriftenartikel
Outeiro, T. F.; Vieira, T. C. R. G.: AI and protein structure and function in neurological disease: relevance to disease management. Nature Reviews Neurology 19 (8), S. 453 - 454 (2023)
52.
Zeitschriftenartikel
Outeiro, T. F.; Alcalay, R. N.; Antonini, A.; Attems, J.; Bonifati, V.; Cardoso, F.; Chesselet, M.-F.; Hardy, J.; Madeo, G.; McKeith, I. et al.; Mollenhauer, B.; Moore, D. J.; Rascol, O.; Schlossmacher, M. G.; Soreq, H.; Stefanis, L.; Ferreira, J. J.: Defining the riddle in order to solve it: There is more than one "Parkinson's Disease". Movement Disorders 38 (7), S. 1127 - 1142 (2023)
53.
Zeitschriftenartikel
Silva, J. L.; Foguel, D.; Ferreira, V. F.; Vieira, T. C. R. G.; Marques, M. A.; Ferretti, G. D. S.; Outeiro, T. F.; Cordeiro, Y.; de Oliveira, G. A. P.: Targeting Biomolecular Condensation and Protein Aggregation against Cancer. Chemical Reviews 123 (14), S. 9094 - 9138 (2023)
54.
Zeitschriftenartikel
Domingos, J.; Teixeira Bastos, M. d. C.; Couto, R.; Cameira, A. R.; Cardoso, A. L.; Reffóios, A.; Magalhães, S.; Massano, J.; Outeiro, T. F.: People with early onset Parkinson’s disease: empowered to improve care. Journal of Parkinson's Disease: JPD 13 (4), S. 633 - 636 (2023)
55.
Zeitschriftenartikel
Gatzemeier, L. M.; Meyer, F.; Diederichsen, U.; Outeiro, T. F.: Chemical Synthesis of Alpha-Synuclein Proteins via Solid-Phase Peptide Synthesis and Native Chemical Ligation. Chemistry – A European Journal 29 (33), e202300649 (2023)
56.
Zeitschriftenartikel
Rosado-Ramos, R.; Poças, G. M.; Marques, D.; Foito, A.; Sevillano, D. M.; Lopes-da-Silva, M.; Gonçalves, L. G.; Menezes, R.; Ottens, M.; Stewart, D. et al.; de Opakua, A. I.; Zweckstetter, M.; Seabra, M. C.; Mendes, C. S.; Outeiro, T. F.; Domingos, P. M.; Santos, C. N.: Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage. Nature Communications 14, 1918 (2023)
57.
Zeitschriftenartikel
Xylaki, M.; Paiva, I.; Al-Azzani, M.; Gerhardt, E.; Jain, G.; Islam, M. R.; Vasili, E.; Wassouf, Z.; Schulze-Hentrich, J. M.; Fischer, A. et al.; Outeiro, T. F.: miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy. Journal of Parkinson's Disease: JPD 13 (2), S. 179 - 196 (2023)
58.
Zeitschriftenartikel
Quesnel, A.; Coles, N.; Angione, C.; Dey, P.; Polvikoski, T. M.; Outeiro, T. F.; Islam, M.; Khundakar, A. A.; Filippou, P. S.: Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy. BMC Cancer 23, 174 (2023)
59.
Zeitschriftenartikel
Outeiro, T. F.; El-Agnaf, O. M.: The immune system in Parkinson's disease: From biology to diagnosis and therapeutic targets. Neurobiology of Disease 177, 105995 (2023)
60.
Zeitschriftenartikel
Habek, M.; Blazekovic, A.; Gotovac Jercic, K.; Pivac, N.; Outeiro, T. F.; Borovecki, F.; Brinar, V.: Genome-Wide Expression Profile in People with Optic Neuritis Associated with Multiple Sclerosis. Biomedicines 11 (8), 2209 (2023)
61.
Zeitschriftenartikel
Marsili, L.; Sharma, J.; Outeiro, T. F.; Colosimo, C.: Stem Cell Therapies in Movement Disorders: Lessons from Clinical Trials. Biomedicines 11 (2), 505 (2023)
62.
Zeitschriftenartikel
Cullinane, P. W.; de Fernandez, E. P.; König, A.; Outeiro, T. F.; Jaunmuktane, Z.; Warner, T. T.: Type 2 Diabetes and Parkinson's Disease: A Focused Review of Current Concepts. Movement Disorders 38 (2), S. 162 - 177 (2022)
63.
Zeitschriftenartikel
Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M. et al.; Gollisch, T.; Outeiro, T. F.: Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, S. 2397 - 2422 (2022)
64.
Zeitschriftenartikel
Berkhoudt Lassen, L.; Schneider Thomsen, M.; Basso, E.; Füchtbauer, E.-M.; Füchtbauer, A.; Outeiro, T. F.; Jensen, P. H.; Moos, T.: Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation. Cells 11 (22), 3673 (2022)
65.
Zeitschriftenartikel
Brás, I. C.; Khani, M. H.; Riedel, D.; Parfentev, I.; Gerhardt, E.; van Riesen, C.; Urlaub, H.; Gollisch, T.; Outeiro, T. F.: Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 269, 104721 (2022)
66.
Zeitschriftenartikel
Magalhaes, R. S. S.; Boechat, F. C.; Brasil, A. A.; Neto, J. R. M.; Ribeiro, G. D.; Paranhos, L. H.; de Souza, N. N.; Vieira, T.; Outeiro, T. F.; Neves, B. C. et al.; Eleutherio, E. C. A.: Hexokinase 2: The preferential target of trehalose-6-phosphate over hexokinase 1. Journal of Cellular Biochemistry (2022)
67.
Zeitschriftenartikel
Koss, D. J.; Erskine, D.; Porter, A.; Palmoski, P.; Menon, H.; Todd, O. G. J.; Leite, M.; Attems, J.; Outeiro, T. F.: Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies. Acta Neuropathologica Communications 10 (1), 98 (2022)
68.
Zeitschriftenartikel
Domingues, R.; Sant'Anna, R.; Carvalho da Fonseca, A. C.; Robbs, B. K.; Foguel, D.; Outeiro, T. F.: Extracellular alpha-synuclein: Sensors, receptors, and responses. Neurobiology of Disease 168, 105696 (2022)
69.
Zeitschriftenartikel
Oliveira, L. M. A.; Gasser, T.; Edwards, R.; Zweckstetter, M.; Melki, R.; Stefanis, L.; Lashuel, H. A.; Sulzer, D.; Vekrellis, K.; Halliday, G. M. et al.; Tomlinson, J. J.; Schlossmacher, M.; Jensen, P. H.; Schulze-Hentrich, J.; Riess, O.; Hirst, W.D.; El-Agnaf, O.; Mollenhauer, B.; Lansbury, P.; Outeiro, T. F.: Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)
70.
Zeitschriftenartikel
Wong-Guerra, M.; Montano-Peguero, Y.; Ramírez-Sánchez, J.; Jiménez-Martin, J.; Fonseca-Fonseca, L. A.; Hernández-Enseñat, D.; Nonose, Y.; Valdés, O.; Mondelo-Rodriguez, A.; Ortiz-Miranda, Y. et al.; Bergado, G.; Carmenate, T.; Soto del Valle, R. M.; Pardo-Andreu, G.; Outeiro, T. F.; Padrón-Yaquis, A. S.; Martimbianco de Assis, A.; O Souza, D.; Nuñez-Figueredo, Y.: JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats. NeuroToxicology 87, S. 70 - 85 (2021)
71.
Zeitschriftenartikel
Masaracchia, C.; Koenig, A.; Valiente-Gabioud, A. A.; Peralta, P.; Favretto, F.; Strohäker, T.; Lazaro, D. F.; Zweckstetter, M.; Fernandez, C. O.; Outeiro, T. F.: Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2020)
72.
Zeitschriftenartikel
Vaz, R.; Chapela, D.; Coelho, J.; Lopez, L.; Ferreira, J.; Alfonso, N.; Sousa, S.; Outeiro, T. F.: Tapentadol Prevent Motor Impairments in a Mouse Model of Dyskinesia. Neuroscience 404, S. 58 - 71 (2020)
73.
Zeitschriftenartikel
Brasil, A.D.; de Carvalho, M.D.C.; Gerhardt, E.; Queiroz, D.D.; Pereira, M.D.; Outeiro, T. F.; Eleutherio, E.C.A.: Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1. Proceedings of the National Academy of Sciences of the United States of America 116 (51), S. 25991 - 2600 (2019)
74.
Zeitschriftenartikel
Szegö, É. M.; Dominguez-Meijide, A.; Gerhardt, E.; König, A.; Koss, D. J.; Li, W.; Pinho, R.; Fahlbusch, C.; Johnson, M.; Santos, P. et al.; Villar-Piqué, A.; Thom, T.; Rizzoli, S.; Schmitz, M.; Li, J.; Zerr, I.; Attems, J.; Jahn, O.; Outeiro, T. F.: Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 28, S. 65 - 77 (2019)
75.
Zeitschriftenartikel
Rossetti, G.; Kless, A.; Lai, L.; Outeiro, T. F.; Carloni, P.: Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions 47, S. 909 - 918 (2019)
76.
Zeitschriftenartikel
Wu, J.; Ardah, M.; Haikal, C.; Svanbergsson, A.; Diepenbroek, M.; Vaikath, N. N.; Li, W.; Wang, Z.-Y.; Outeiro, T. F.; El-Agnaf, O. M. et al.; Li, J.-Y.: Dihydromyricetin and salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Translational neurodegeneration 8, 18 (2019)
77.
Zeitschriftenartikel
Outeiro, T. F.; Harvey, K.; Dominguez-Meijide, A.; Gerhardt, E.: LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? Biochemical Society Transactions 47 (3), S. 827 - 838 (2019)
78.
Zeitschriftenartikel
Candelise, N.; Schmitz, M.; Llorens, F.; Villar-Piqué, A.; Cramm, M.; Thom, T.; da Silva Correia, S. M.; Gomes da Cunha, J. E.; Möbius, W.; Outeiro, T. F. et al.; González Álvarez, V.; Banchelli, M.; D'Andrea, C.; de Angelis, M.; Zafar, S.; Rabano, A.; Matteini, P.; Zerr, I.: Seeding variability of different alpha synuclein strains in synucleinopathies. Annals of Neurology 85 (5), S. 691 - 703 (2019)
79.
Zeitschriftenartikel
Vasili, E.; Dominguez-Meijide, A.; Outeiro, T. F.: Spreading of α-synuclein and tau: a systematic comparison of the mechanisms involved. Frontiers in Molecular Neuroscience 12, 107 (2019)
80.
Zeitschriftenartikel
Carija, A.; Pinheiro, F.; Pujols, J.; Brás, I. C.; Fernandes Lázaro, D.; Santambrogio, C.; Grandori, R.; Outeiro, T. F.; Navarro, S.; Ventura, S.: Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity. Redox Biology 22, 101135 (2019)
81.
Zeitschriftenartikel
Harvey, K.; Outeiro, T. F.: The role of LRRK2 in cell signalling. Biochemical Society Transactions 47, S. 197 - 207 (2019)
82.
Zeitschriftenartikel
Prasad, V.; Wasser, Y.; Hans, F.; Goswami, A.; Katona, I.; Outeiro, T. F.; Kahle, P. J.; Schulz, J. B.; Voigt, A.: Monitoring α-synuclein multimerization in vivo. The FASEB Journal 33 (2), S. 2116 - 2131 (2019)
83.
Zeitschriftenartikel
Outeiro, T. F.; Koss, D. J.; Erskine, D.; Walker, L.; Kurzawa-Akanbi, M.; Burn, D.; Donaghy, P.; Morris, C.; Taylor, J.-P.; Thomas, A. et al.; Atterns, J.; McKeith, I.: Dementia with Lewy bodies: an update and outlook. Molecular neurodegeneration 14, 5 (2019)
84.
Zeitschriftenartikel
Chiang, A. N.; Liang, M.; Dominguez-Meijide, A.; Masaracchia, C.; Goeckeler-Fried, J. L.; Mazzone, C. S.; Newhouse, D. W.; Kendsersky, N. M.; Yates, M. E.; Manos-Turvey, A. et al.; Needham, P. G.; Outeiro, T. F.; Wipf, P.; Brodsky, J. L.: Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry 27 (1), S. 79 - 91 (2019)
85.
Zeitschriftenartikel
Pinho , R.; Paiva, I.; Jercic, K. G.; Fonseca-Ornelas, L.; Gerhardt, E.; Fahlbusch, C.; Garcia-Esparcia, P.; Kerimoglu, C.; Pavlou, M. A.S.; Villar-Piqué, A. et al.; Szegö, É.; Lopes da Fonseca, T.; Odoardi, F.; Soeroes, S.; Rego, A. C.; Fischle, W.; Schwamborn, J. C.; Meyer, T.; Kügler, S.; Ferrer, I.; Attems, J.; Fischer, A.; Becker, S.; Zweckstetter, M.; Borovecki, F.; Outeiro, T. F.: Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein. Human Molecular Genetics 28 (1), S. 31 - 50 (2019)
86.
Zeitschriftenartikel
Brás, I. C.; Tenreiro, S.; Silva, A. M.; Outeiro, T. F.: Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research 18 (8), foy108 (2018)
87.
Zeitschriftenartikel
Brás, I. C.; Lopes, L. V.; Outeiro, T. F.: Sensing α-Synuclein from the outside via the prion problem: implications for neurodegeneration. Movement Disorders 33 (11), S. 1675 - 1684 (2018)
88.
Zeitschriftenartikel
Biosa, A.; Outeiro, T. F.; Bubacco, L.; Bisaglia, M.: Diabetes mellitus as a risk factor for Parkinson's disease: a molecular point of view. Molecular Neurobiology 55, S. 8754 - 8763 (2018)
89.
Zeitschriftenartikel
Gustafsson, G.; Lööv, C.; Persson, E.; Lázaro, D. F.; Takeda, S.; Bergström, J.; Erlandsson, A.; Sehlin, D.; Balaj, L.; György, B. et al.; Hallbeck, M.; Outeiro, T. F.; Breakefield, X. O.; Hyman, B. T.; Ingelsson, M.: Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells. Cellular and Molecular Neurobiology 38, S. 1539 - 1550 (2018)
90.
Zeitschriftenartikel
Magalhães, R. S.S.; Popova, B.; Braus, G. H.; Outeiro, T. F.; Eleutherio, E. C.A.: The trehalose protective mechanism during thermal stress in Saccharomyces cerevisiae: the roles of Ath1 and Agt1. FEMS Yeast Research 18 (6), foy066 (2018)
91.
Zeitschriftenartikel
Masaracchia, C.; Hnida, M.; Gerhardt, E.; Lopes da Fonseca, T.; Villar-Pique, A.; Branco, T.; Stahlberg, M. A.; Dean, C.; Fernández, C. O.; Milosevic, I. et al.; Outeiro, T. F.: Membrane binding, internalization, and sorting of alpha-synuclein in the cell. Acta Neuropathologica Communications 6, 79 (2018)
92.
Zeitschriftenartikel
Temido-Ferreira, M.; Ferreira, D. G.; Batalha, V. L.; Marques-Morgado, I.; Coelho, J. E.; Pereira, P.; Gomes, R.; Pinto, A.; Carvalho, S.; Canas, P. M. et al.; Cuvelier, L.; Buée-Scherrer, V.; Faivre, E.; Baqi, Y.; Müller, C. E.; Pimentel, J.; Schiffmann, S. N.; Buée, L.; Bader, M.; Outeiro, T. F.; Blum, D.; Cunha, R. A.; Marie, H.; Pousinha, P. A.; Lopes, L. V.: Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors. Molecular Psychiatry, 10.1038/s41380-018-0110-9 (2018)
93.
Zeitschriftenartikel
Macedo, D.; Jardim, C.; Figueira, I.; Almeida, A. F.; McDougall, G. J.; Stewart, D.; Yuste, J. E.; Tomás-Barberán, F. A.; Tenreiro, S.; Outeiro, T. F. et al.; Santos, C. N.: (Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis. Scientific Reports 8, 6965 (2018)
94.
Zeitschriftenartikel
Valiente-Gabioud, A. A.; Riedel, D.; Outeiro, T. F.; Menacho-Márquez, M. A.; Griesinger, C.; Fernández, C. O.: Binding modes of phthalocyanines of amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 114 (5), S. 1036 - 1045 (2018)
95.
Zeitschriftenartikel
Pinho, R.; Wang, B.; Becker, A.; Rothenberger, A.; Outeiro, T. F.; Herrmann-Lingen, C.; Meyer, T.: Attention-deficit/hyperactivity disorder is associated with reduced levels of serum low-density lipoprotein cholesterol in adolescents. Data from the population-based German KiGGS study. World journal of biological psychiatry, 10.1080/15622975.2017.1417636 (2018)
96.
Zeitschriftenartikel
Richter, K. N.; Revelo, N. H.; Seitz, K. J.; Helm, M. S.; Sarkar, D.; Saleeb, R. S.; D'Este, E.; Eberle, J.; Wagner, E.; Vogl, C. et al.; Lazaro, D. F.; Richter, F.; Coy-Vergara, J.; Coceano, G.; Boyden, E. S.; Duncan, R. R.; Hell, S. W.; Lauterbach, M. A.; Lehnart, S. E.; Moser, T.; Outeiro, T. F.; Rehling, P.; Schwappach, B.; Testa, I.; Zapiec, B.; Rizzoli, S. O.: Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO Journal 37 (1), S. 139 - 159 (2018)
97.
Zeitschriftenartikel
Brasil, A. A.; Magalhães, R. S. S.; De Carvalho, M. D. C.; Paiva, I.; Gerhardt, E.; Pereira, M. D.; Outeiro, T. F.; Eleutherio, E. C. A.: Implications of fALS mutations on Sod1 function and oligomerization in cell models. Molecular Neurobiology 55, S. 5269 - 5281 (2018)
98.
Zeitschriftenartikel
Carmona-Gutierrez, D.; Bauer, M. A.; Zimmermann, A.; Aguilera, A.; Austriaco, N.; Ayscough, K.; Balzan, R.; Bar-Nun, S.; Barrientos, A.; Belenky, P. et al.; Blondel, M.; Braun, R. J.; Breitenbach, M.; Burhans, W. C.; Büttner, S.; Cavalieri, D.; Chang, M.; Cooper, K. F.; Côrte-Real, M.; Costa, V.; Cullin, C.; Dawes, I.; Dengjel, J.; Dickman, M. B.; Eisenberg, T.; Fahrenkrog, B.; Fasel, N.; Fröhlich, K.-U.; Gargouri, A.; Giannattasio, S.; Goffrini, P.; Gourlay, C. W.; Grant, C. M.; Greenwood, M. T.; Guaragnella, N.; Heger, T.; Heinisch, J.; Herker, E.; Herrmann, J. M.; Hofer, S.; Jiménez-Ruiz, A.; Jungwirth, H.; Kainz, K.; Kontoyiannis, D. P.; Ludovico, P.; Manon, S.; Martegani, E.; Mazzoni, C.; Megeney, L. A.; Meisinger, C.; Nielsen, J.; Nyström, T.; Osiewacz, H. D.; Outeiro, T. F.; Park, H.-O.; Pendl, T.; Petranovic, D.; Picot, S.; Polčic, P.; Powers, T.; Ramsdale, M.; Rinnerthaler, M.; Rockenfeller, P.; Ruckenstuhl, C.; Schaffrath, R.; Segovia, M.; Severin, F. F.; Sharon, A.; Sigrist, S. J.; Sommer-Ruck, C.; Sousa, M. J.; Thevelein, J. M.; Thevissen, K.; Titorenko, V.; Toledano, M. B.; Tuite, M.; Vögtle, F.-N.; Westermann, B.; Winderickx, J.; Wissing, S.; Wölfl, S.; Zhang, Z. J.; Zhao, R. Y.; Zhou, B.; Galluzzi, L.; Kroemer, G.; Madeo, F.: Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 5 (1), S. 4 - 31 (2018)
99.
Zeitschriftenartikel
König, A.; Miranda, H. V.; Outeiro, T. F.: Alpha-synuclein glycation and the action of anti-diabetic agents in Parkinson's disease. Journal of Parkinson's Disease: JPD 8 (1), S. 33 - 43 (2018)
100.
Zeitschriftenartikel
Paiva, I.; Jain, G.; Lázaro, D. F.; Gotovac Jercic, K.; Hentrich, T.; Kerimoglu, C.; Pinho, R.; Szego, È. M.; Burkhardt, S.; Capece, V. et al.; Halder, R.; Islam, R.; Xylaki, M.; Caldi Gomes, L. A.; Roser, A.-E.; Lingor, P.; Schulze-Hentrich, J. M.; Borovecki, F.; Fischer, A.; Outeiro, T. F.: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function. Neurobiology of Disease 119, S. 121 - 135 (2018)
Zur Redakteursansicht