Publications

2022

Ehrenreich H, Garcia-Agudo LF, Steixner-Kumar AA, Wilke JBH, Butt UJ. (2022) Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance.
Mol Psychiatry. Apr 12 doi: 10.1038/s41380-022-01551-5. Online ahead of print.

 

Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W. (2022) White matter integrity in mice requires continuous myelin synthesis at the inner tongue.
Nat Commun. 13(1):1163.

 

Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kučinskas V, Kučinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M Jr, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadić I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbaşoğlu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Müller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S; Indonesia Schizophrenia Consortium; PsychENCODE; Psychosis Endophenotypes International Consortium; SynGO Consortium, Adolfsson R, Arango C, Baune BT, Belangero SI, Børglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Jönsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Nöthen MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefánsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ, Roussos P, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O'Donovan MC; Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2022) Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Nature. Apr 8. doi: 10.1038/s41586-022-04434-5. Online ahead of print.

 

Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC), Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. (2022) Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
JAMA Psychiatry. 79(3):260-269.

 

Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, Müller-Myhsok B, Świątkowska B, Schulze TG, Nöthen MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Landén M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Baune BT, Air T, Preisig M, Uher R, Levinson DF, Weissman MM, Potash JB, Shi J, Knowles JA, Perlis RH, Lucae S, Boomsma DI, Penninx BWJH, Hottenga JJ, de Geus EJC, Willemsen G, Milaneschi Y, Tiemeier H, Grabe HJ, Teumer A, Van der Auwera S, Völker U, Hamilton SP, Magnusson PKE, Viktorin A, Mehta D, Mullins N, Adams MJ, Breen G, McIntosh AM, Lewis CM; Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium; iPSYCH, Hougaard DM, Nordentoft M, Mors O, Mortensen PB, Werge T, Als TD, Børglum AD, Petryshen TL, Smoller JW, Goldstein JM. (2022) Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Biol Psychiatry. 91, 102-117


2021

Arinrad S, Wilke JBH, Seelbach A, Doeren J, Hindermann M, Butt UJ, Steixner-Kumar AA, Spieth L, Ronnenberg A, Pan H, Berghoff SA, Hollmann M, Lühder F, Nave KA, Bechter K, Ehrenreich H.(2021) NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance.
Mol Psychiatry. Dec 6. doi: 10.1038/s41380-021-01392-8. Online ahead of print.

 

Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Yang J, Visscher PM, Wray NR.(2021) A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Biol Psychiatry. 90, 611-620

 

Wilke JBH, Hindermann M, Berghoff SA, Zihsler S, Arinrad S, Ronnenberg A, Barnkothe N, Steixner-Kumar AA, Röglin S, Stöcker W, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis. (2021)
Mol Psychiatry. Jul 30. doi: 10.1038/s41380-021-01238-3. Online ahead of print.

 

Begemann M, Gross O, Wincewicz D, Hardeland R, Daguano Gastaldi V, Vieta E, Weissenborn K, Miskowiak KW, Moerer O, Ehrenreich H.(2021) Addressing the 'hypoxia paradox' in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues.
Mol Med. 27, 120

 

Hodel F, Chong AY, Scepanovic P, Xu ZM, Naret O, Thorball CW, Rüeger S, Marques-Vidal P, Vollenweider P, Begemann M, Ehrenreich H, Brenner N, Bender N, Waterboer T, Mentzer AJ, Hill AVS, Hammer C, Fellay J. (2021) Human genomics of the humoral immune response against polyomaviruses.
Virus Evol. 11, veab058

 

 

Fernandez Garcia-Agudo L, Steixner-Kumar AA, Curto Y, Barnkothe N, Hassouna I, Jähne S, Butt UJ, Grewe K, Weber MS, Green K, Rizzoli S, Nacher J, Nave KA, Ehrenreich H. (2021) Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus.
Cell Rep. 36, 109548

 

Wilke JBH, Hindermann M, Moussavi A, Butt UJ, Dadarwal R, Berghoff SA, Sarcheshmeh AK, Ronnenberg A, Zihsler S, Arinrad S, Hardeland R, Seidel J, Lühder F, Nave KA, Boretius S, Ehrenreich H. (2021) Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis.
Acta Neuropathol Commun. 9, 121

 

Deutsch NR, Worthmann H, Steixner-Kumar AA, Schuppner R, Grosse GM, Pan H, Gabriel MM, Hasse I, van Gemmeren T, Lichtinghagen R, Ehrenreich H, Weissenborn K. (2021) Autoantibodies against the NMDAR subunit NR1 are associated with neuropsychiatric outcome after ischemic stroke.
Brain Behav Immun. May 16:S0889-1591(21)00192-6. doi: 10.1016/j.bbi.2021.05.011. Online ahead of print.

 

Steixner-Kumar AA, Daguano Gastaldi V, Seidel J, Rosenberger A, Begemann M, Ehrenreich H.(2021) Preadult polytoxicomania-strong environmental underpinnings and first genetic hints.
Mol Psychiatry. Apr 7. doi: 10.1038/s41380-021-01069-2. Online ahead of print.   

 

Butt UJ, Hassouna I, Fernandez Garcia-Agudo L, Steixner-Kumar AA, Depp C, Barnkothe N, Zillmann MR, Ronnenberg A, Bonet V, Goebbels S, Nave KA, Ehrenreich H. (2021) CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge.
Int J Mol Sci. 22, 3164

 

Ehrenreich H, Neubauer AP, Miskowiak K. (2021) Effect of Early Recombinant Human Erythropoietin on Neurodevelopmental Outcomes at Age 5 Years.
JAMA. 325, 1470-1471

 

Butt UJ, Steixner-Kumar AA, Depp C, Sun T, Hassouna I, Wüstefeld L, Arinrad S, Zillmann MR, Schopf N, Fernandez Garcia-Agudo L, Mohrmann L, Bode U, Ronnenberg A, Hindermann M, Goebbels S, Bonn S, Katschinski DM, Miskowiak KW, Nave KA, Ehrenreich H.(2021) Hippocampal neurons respond to brain activity with functional hypoxia.
Mol Psychiatry. Feb 9. doi: 10.1038/s41380-020-00988-w. Online ahead of print. PMID: 33564132.  

 

Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, Bækvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stefánsson H, Stefánsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ.(2021) A polygenic resilience score moderates the genetic risk for schizophrenia.
Mol Psychiatry. 26, 800-815

 

Pan H, Steixner-Kumar AA, Seelbach A, Deutsch N, Ronnenberg A, Tapken D, von Ahsen N, Mitjans M, Worthmann H, Trippe R, Klein-Schmidt C, Schopf N, Rentzsch K, Begemann M, Wienands J, Stöcker W, Weissenborn K, Hollmann M, Nave KA, Lühder F, Ehrenreich H. (2021) Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury.
Mol Psychiatry. 26, 2471-2482

 

Ehrenreich H, Wilke J, Steixner-Kumar AA (2021) Spontaneous serum autoantibody fluctuations: To be or not to be.
Mol Psychiatry. 26, 1723-1725


2020

Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA (2020).
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
Nat Genet. 51, 659-674
 

Ehrenreich H, Weissenborn K, Begemann M, Busch M, Vieta E, Miskowiak K. (2020) Erythropoietin as candidate for supportive treatment of severe COVID-19.
Molecular Medicine. 26, 58

 

Begemann M, Seidel J, Poustka L, Ehrenreich H. (2020) Accumulated environmental risk in young refugees: A prospective evaluation.
EClinicalMedicine. 22, 100345

 

Ehrenreich H, Neubauer AP, Miskowiak K. (2020) Erythropoietin in Preterm Infants.
N Engl J Med. 382, 1862

 

Wakhloo D, Scharkowski F, Curto Y, Butt UJ, Bansal V, Steixner-Kumar A, Wüstefeld L, Rajput A, Arinrad S, Zillmann MR, Seelbach A, Hassouna I, Schneider K, Ibrahim AQ, Werner HB, Martens H, Miskowiak K, Wojcik SM, Bonn S, Nacher J, Nave KA, Ehrenreich H. (2020) Functional Hypoxia Drives Neuroplasticity and Neurogenesis via Brain Erythropoietin
Nat Commun. 11, 1313

 

Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Boehnke M, Kimberly RP, Kaufman KM, Harley JB, Langefeld CD, Seidman CE, Pato MT, Pato CN, Ophoff RA, Graham RR, Criswell LA, Vyse TJ, McCarroll SA. (2020) Complement genes contribute sex-biased vulnerability in diverse disorders.
Nature. 582, 577-581

 

Seidel J, Bockhop F, Mitkovski M, Martin S, Ronnenberg A, Krueger-Burg D, Schneider K, Röhse H, Wüstefeld L, Cosi F, Bröking K, Schacht A, Ehrenreich H (2020).
Vascular response to social cognitive performance measured by infrared thermography: A translational study from mouse to man. FASEB Bioadv
FASEB Bioadv. 2, 18-32


2019

Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, Martens H, Weber MS, Boretius S, Nave KA, Ehrenreich H (2019).
Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.
FASEB J. 33, 8634-8647
 

Pan H, Oliveira B, Saher G, Dere E, Tapken D, Mitjans M, Seidel J, Wesolowski J, Wakhloo D, Klein-Schmidt C, Ronnenberg A, Schwabe K, Trippe R, Mätz-Rensing K, Berghoff S, Al-Krinawe Y, Martens H, Begemann M, Stöcker W, Kaup FJ, Mischke R, Boretius S, Nave KA, Krauss JK, Hollmann M, Lühder F, Ehrenreich H. (2019) Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model.
Molecular Psychiatry. 24, 1489-1501

 

Mitjans M, Seidel J, Begemann M, Bockhop F, Moya-Higueras J, Bansal V, Wesolowski J, Seelbach A, Ibáñez MI, Kovacevic F, Duvar O, Fañanás L, Wolf HU, Ortet G, Zwanzger P, Klein V, Lange I, Tänzer A, Dudeck M, Penke L, van Elst LT, Bittner RA, Schmidmeier R, Freese R, Müller-Isberner R, Wiltfang J, Bliesener T, Bonn S, Poustka L, Müller JL, Arias B, Ehrenreich H. (2019) Violent aggression predicted by multiple pre-adult environmental hits.
Molecular Psychiatry. 24, 1549-1564

 

Nave KA, Ehrenreich H (2019).
Time to revisit oligodendrocytes in multiple sclerosis.
Nat Med. 25, 36-366


2018

Oliveira B, Ehrenreich H (2018).
Pursuing functional connectivity in NMDAR1 autoantibody carriers.
Lancet Psychiatry. 5, 21-22

Nave KA, Ehrenreich H (2018).
A bloody brake on myelin repair.
Nature 553, 31-32

Ehrenreich H, Mitjans M, Van der Auwera S, Centeno TP, Begemann M, Grabe HJ, Bonn S, Nave KA (2018).
OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals.
Mol Psychiatry. 23, 476-486


Dere E, Ronnenberg A, Tampe B, Arinrad S, Schmidt M, Zeisberg E, Ehrenreich H (2018).
Cognitive, emotional and social phenotyping of mice in an observer-independent setting.
Neurobiol Learn Mem. 150, 136-150
 


Ehrenreich H (2018).
Autoantibodies against N-methyl-d-aspartate receptor 1 in health and disease.
Curr Opin Neurol. 31, 306-312
 

Ni G, Moser G; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray NR, Lee SH (2018).
Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.
Am J Hum Genet. 102, 1185-1194

Ursini G, Punzi G, Chen Q, Marenco S, Robinson JF, Porcelli A, Hamilton EG, Mitjans M, Maddalena G, Begemann M, Seidel J, Yanamori H, Jaffe AE, Berman KF, Egan MF, Straub RE, Colantuoni C, Blasi G, Hashimoto R, Rujescu D, Ehrenreich H, Bertolino A, Weinberger DR (2018).
Convergence of placenta biology and genetic risk for schizophrenia.
Nat Med. 24, 792-801

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2018).
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.
Cell 173, 1705-1715

Oliveira B, Mitjans M, Nitsche MA, Kuo MF, Ehrenreich H (2018).
Excitation-inhibition dysbalance as predictor of autistic phenotypes.
J Psychiatr Res. 104, 96-99

Bansal V, Mitjans M, Burik CAP, Linnér RK, Okbay A, Rietveld CA, Begemann M, Bonn S, Ripke S, de Vlaming R, Nivard MG, Ehrenreich H, Koellinger PD (2018).
Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.
Nat Commun. 9, 3078-3078

Babaev O, Cruces-Solis H, Piletti Chatain C, Hammer M, Wenger S, Ali H, Karalis N, de Hoz L, Schlüter OM, Yanagawa Y, Ehrenreich H, Taschenberger H, Brose N, Krueger-Burg D (2018).
IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses.
Nat Commun. 9, 5400-5400


2017

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium.; Schizophrenia Working Group of the Psychiatric Genomics Consortium (2017).
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
Nat Commun. 8, 14774-14774

Ehrenreich H (2017).
Autoantibodies against the N-Methyl-d-Aspartate Receptor Subunit NR1: Untangling Apparent Inconsistencies for Clinical Practice.
Front Immunol. 8, 181-181

Ehrenreich H (2017).
The impact of environment on abnormal behavior and mental disease: To alleviate the prevalence of mental disorders, we need to phenotype the environment for risk factors.
EMBO Rep. 18, 661-665

Bonnas C, Wüstefeld L, Winkler D, Kronstein-Wiedemann R, Dere E, Specht K, Boxberg M, Tonn T, Ehrenreich H, Stadler H, Sillaber I (2017).
EV-3, an endogenous human erythropoietin isoform with distinct functional relevance.
Sci Rep. 7, 3684-3684

Lepeta K, Purzycka KJ, Pachulska-Wieczorek K, Mitjans M, Begemann M, Vafadari B, Bijata K, Adamiak RW, Ehrenreich H, Dziembowska M, Kaczmarek L (2017).
A normal genetic variation modulates synaptic MMP-9 protein levels and the severity of schizophrenia symptoms.
EMBO Mol Med. 9, 1100-1116

Mitjans M, Begemann M, Ju A, Dere E, Wüstefeld L, Hofer S, Hassouna I, Balkenhol J, Oliveira B, van der Auwera S, Tammer R, Hammerschmidt K, Völzke H, Homuth G, Cecconi F, Chowdhury K, Grabe H, Frahm J, Boretius S, Dandekar T, Ehrenreich H (2017).
Sexual dimorphism of AMBRA1-related autistic features in human and mouse.
Transl Psychiatry. 7, e1247-e1247

Bartels C, Wagner M, Wolfsgruber S, Ehrenreich H, Schneider A; Alzheimer’s Disease Neuroimaging Initiative (2017).
Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer's Dementia in Individuals With Previous Depression.
Am J Psychiatry. 175, 232-241

Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, Bittner RA, Pan H, Goebbels S, Begemann M, Gerwig UC, Langner S, Werner HB, Kittel-Schneider S, Homuth G, Davatzikos C, Völzke H, West BL, Reif A, Grabe HJ, Boretius S, Ehrenreich H, Nave KA (2017).
Microglia ablation alleviates myelin-associated catatonic signs in mice.
J Clin Invest. 128, 734-745
 


2016

Hassouna I, Ott C, Wüstefeld L, Offen N, Neher RA, Mitkovski M, Winkler D, Sperling S, Fries L, Goebbels S, Vreja IC, Hagemeyer N, Dittrich M, Rossetti MF, Kröhnert K, Hannke K, Boretius S, Zeug A, Höschen C, Dandekar T, Dere E, Neher E, Rizzoli SO, Nave KA, Sirén AL, Ehrenreich H (2016).
Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus.
Mol Psychiatry. 21, 1752-1767
 

Wüstefeld L, Winkler D, Janc OA, Hassouna I, Ronnenberg A, Ostmeier K, Müller M, Brose N, Ehrenreich H, Wojcik SM (2016).
Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition.
J Neurochem. 136, 698-705

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium 2; Enigma Consortium, O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF (2016).
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
Nat Neurosci. 19, 420-431

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA (2016).
Schizophrenia risk from complex variation of complement component 4.
Nature 530, 177-183

Castillo-Gomez E, Kästner A, Steiner J, Schneider A, Hettling B, Poggi G, Ostehr K, Uhr M, Asif AR, Matzke M, Schmidt U, Pfander V, Hammer C, Schulz TF, Binder L, Stöcker W, Weber F, Ehrenreich H (2016).
The brain as immunoprecipitator of serum autoantibodies against N-Methyl-D-aspartate receptor subunit NR1.
Ann Neurol. 79, 144-151

Tuoc T, Dere E, Radyushkin K, Pham L, Nguyen H, Tonchev AB, Sun G, Ronnenberg A, Shi Y, Staiger JF, Ehrenreich H, Stoykova A (2016).
Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.
Mol Neurobiol. 54, 4618-4635

Poggi G, Boretius S, Möbius W, Moschny N, Baudewig J, Ruhwedel T, Hassouna I, Wieser GL, Werner HB, Goebbels S, Nave KA, Ehrenreich H (2016).
Cortical network dysfunction caused by a subtle defect of myelination.
Glia 64, 2025-2040

Castillo-Gómez E, Oliveira B, Tapken D, Bertrand S, Klein-Schmidt C, Pan H, Zafeiriou P, Steiner J, Jurek B, Trippe R, Prüss H, Zimmermann WH, Bertrand D, Ehrenreich H, Hollmann M (2016).
All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class.
Mol Psychiatry. 22, 1776-1784
 

Krueger-Burg D, Winkler D, Mitkovski M, Daher F, Ronnenberg A, Schlüter OM, Dere E, Ehrenreich H (2016).
The SocioBox: A Novel Paradigm to Assess Complex Social Recognition in Male Mice.
Front Behav Neurosci. 10, 151-151
 


2015

Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N, Daly MJ, Price AL, Neale BM (2015).
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nat Genet. 47, 291-295

Netrakanti PR, Cooper BH, Dere E, Poggi G, Winkler D, Brose N, Ehrenreich H (2015).
Fast Cerebellar Reflex Circuitry Requires Synaptic Vesicle Priming by Munc13-3.
Cerebellum 14, 264-283
 

Hammer C, Wanitchakool P, Sirianant L, Papiol S, Monnheimer M, Faria D, Ousingsawat J, Schramek N, Schmitt C, Margos G, Michel A, Kraiczy P, Pawlita M, Schreiber R, Schulz TF, Fingerle V, Tumani H, Ehrenreich H, Kunzelmann K (2015).
A coding variant of ANO10, affecting volume regulation of macrophages, is associated with Borrelia seropositivity.
Mol Med. 21, 26-37

Zerche M, Weissenborn K, Ott C, Dere E, Asif AR, Worthmann H, Hassouna I, Rentzsch K, Tryc AB, Dahm L, Steiner J, Binder L, Wiltfang J, Sirén AL, Stöcker W, Ehrenreich H (2015).
Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke.
Stroke 46, 1180-1186

Mitkovski M, Dahm L, Heinrich R, Monnheimer M, Gerhart S, Stegmüller J, Hanisch UK, Nave KA, Ehrenreich H (2015).
Erythropoietin dampens injury-induced microglial motility.
J Cereb Blood Flow Metab. 35, 1233-1236

Kästner A, Begemann M, Michel TM, Everts S, Stepniak B, Bach C, Poustka L, Becker J, Banaschewski T, Dose M, Ehrenreich H (2015).
Autism beyond diagnostic categories: characterization of autistic phenotypes in schizophrenia.
BMC Psychiatry. 15, 115-115

Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D (2015).
Neuroligin 2 Deletion Alters Inhibitory Synapse Function and Anxiety-Associated Neuronal Activation in the Amygdala.
Neuropharmacology 100, 56-65

Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, Stadler H, Kawabe H, Zimmermann WH, Nave KA, Schulz-Schaeffer W, Jahn O, Ehrenreich H (2015).
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Mol Med. 1, 803-815

Stepniak B, Papiol S, Hammer C, Ramin A, Everts S, Hennig L, Begemann M, Ehrenreich H (2015).
Accumulated environmental risk determining age at schizophrenia onset: a deep phenotyping-based study.
Lancet Psychiatry. 1, 444-453

Hammer M, Krueger-Burg D, Tuffy LP, Cooper BH, Taschenberger H, Goswami SP, Ehrenreich H, Jonas P, Varoqueaux F, Rhee JS, Brose N (2015).
Perturbed Hippocampal Synaptic Inhibition and ?-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.
Cell Rep. 13, 516-523

Hammer C, Begemann M, McLaren PJ, Bartha I, Michel A, Klose B, Schmitt C, Waterboer T, Pawlita M, Schulz TF, Ehrenreich H, Fellay J (2015).
Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses.
Am J Hum Genet. 97, 738-743
 

Ehrenreich H, Steiner J (2015).
Serum autoantibodies against N-methyl-D-aspartate receptor subunit NR1 are no disease indicator.
Ann Neurol. 77, 184


Stepniak B, Kästner A, Poggi G, Mitjans M, Begemann M, Hartmann A, Van der Auwera S, Sananbenesi F, Krueger-Burg D, Matuszko G, Brosi C, Homuth G, Völzke H, Benseler F, Bagni C, Fischer U, Dityatev A, Grabe HJ, Rujescu D, Fischer A, Ehrenreich H (2015).
Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.
EMBO Mol Med. 7, 1565-1579

Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK (2015).
CD14 is a key organizer of microglial responses to CNS infection and injury.
Glia 64, 635-649
 


2014

Tantra M, Hammer C, Kästner A, Dahm L, Begemann M, Bodda C, Hammerschmidt K, Giegling I, Stepniak B, Castillo Venzor A, Konte B, Erbaba B, Hartmann A, Tarami A, Schulz-Schaeffer W, Rujescu D, Mannan AU, Ehrenreich H (2014).
Mild expression differences of MECP2 influencing aggressive social behavior.
EMBO Mol Med. 6, 662-684

Nave KA, Ehrenreich H (2014).
Myelination and Oligodendrocyte Functions in Psychiatric Diseases.
JAMA Psychiatry. 71, 582-584

 

Ehrenreich H, Nave KA (2014).
Phenotype-Based Genetic Association Studies (PGAS)-Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes.
Genes (Basel) 5, 97-105

Ju A, Hammerschmidt K, Tantra M, Krueger D, Brose N, Ehrenreich H (2014).
Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.
Behav Brain Res. 270, 159-164

Dahm L, Ott C, Steiner J, Stepniak B, Teegen B, Saschenbrecker S, Hammer C, Borowski K, Begemann M, Lemke S, Rentzsch K, Probst C, Martens H, Wienands J, Spalletta G, Weissenborn K, Stöcker W, Ehrenreich H (2014).
Seroprevalence of autoantibodies against brain antigens in health and disease.
Ann Neurol. 77, 184-184

Dere E, Dahm L, Lu D, Hammerschmidt K, Ju A, Tantra M, Kästner A, Chowdhury K, Ehrenreich H (2014).
Heterozygous ambra1 deficiency in mice: a genetic trait with autism-like behavior restricted to the female gender.
Front Behav Neurosci. 8, 181-181
 

Hammer C, Zerche M, Schneider A, Begemann M, Nave KA, Ehrenreich H (2014).
Apolipoprotein E4 carrier status plus circulating anti-NMDAR1 autoantibodies: association with schizoaffective disorder.
Mol Psychiatry. 19, 1054-1056

Gurvich A, Begemann M, Dahm L, Sargin D, Miskowiak K, Ehrenreich H (2014).
A role for prostaglandins in rapid cycling suggested by episode-specific gene expression shifts in peripheral blood mononuclear cells: a preliminary report.
Bipolar Disord. 16, 881-888

Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014).
Biological insights from 108 schizophrenia-associated genetic loci.
Nature 511, 421-427

Miskowiak KW, Ehrenreich H, Christensen EM, Kessing LV, Vinberg M (2014).
Recombinant human erythropoietin to target cognitive dysfunction in bipolar disorder: a double-blind, randomized, placebo-controlled phase 2 trial.
J Clin Psychiatry. 75, 1347-55

Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium (2014).
Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases.
Am J Hum Genet. 95, 535-552

Miskowiak KW, Vinberg M, Macoveanu J, Ehrenreich H, Køster N, Inkster B, Paulson OB, Kessing LV, Skimminge A, Siebner HR (2014).
Effects of Erythropoietin on Hippocampal Volume and Memory in Mood Disorders.
Biol Psychiatry. 78, 270-277


2013

El-Kordi A, Kästner A, Grube S, Klugmann M, Begemann M, Sperling S, Hammerschmidt K, Hammer C, Stepniak B, Patzig J, de Monasterio-Schrader P, Strenzke N, Flügge G, Werner HB, Pawlak R, Nave KA, Ehrenreich H (2013).
A single gene defect causing claustrophobia.
Transl Psychiatry. 3, e254-e254

Wojcik SM, Tantra M, Stepniak B, Man KN, Müller-Ribbe K, Begemann M, Ju A, Papiol S, Ronnenberg A, Gurvich A, Shin Y, Augustin I, Brose N, Ehrenreich H (2013).
Genetic Markers of a Munc13 Protein Family Member, BAIAP3, Are Gender-Specifically Associated with Anxiety and Benzodiazepine Abuse in Mouse and Man.
Mol Med. 19, 135-148

Hammer C, Stepniak B, Schneider A, Papiol S, Tantra M, Begemann M, Sirén AL, Pardo LA, Sperling S, Mohd Jofrry S, Gurvich A, Jensen N, Ostmeier K, Lühder F, Probst C, Martens H, Gillis M, Saher G, Assogna F, Spalletta G, Stöcker W, Schulz TF, Nave KA, Ehrenreich H (2013).
Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity.
Mol Psychiatry. 19, 1143-1149

El-Kordi A, Winkler D, Hammerschmidt K, Kästner A, Krueger D, Ronnenberg A, Ritter C, Jatho J, Radyushkin K, Bourgeron T, Fischer J, Brose N, Ehrenreich H (2013).
Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.
Behav Brain Res. 251, 41-49
 

Miskowiak KW, Vinberg M, Christensen EM, Bukh JD, Harmer CJ, Ehrenreich H, Kessing LV (2013).
Recombinant Human Erythropoietin for Treating Treatment-Resistant Depression: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial.
Neuropsychopharmacology 39, 1399-1408

Offen N, Flemming J, Kamawal H, Ahmad R, Wolber W, Geis C, Zaehres H, Schöler HR, Ehrenreich H, Müller AM, Sirén AL (2013).
Effects of erythropoietin in murine-induced pluripotent cell-derived panneural progenitor cells.
Mol Med. 19, 399-408
 


2012

Hagemeyer N, Goebbels S, Papiol S, Kästner A, Hofer S, Begemann M, Gerwig UC, Boretius S, Wieser GL, Ronnenberg A, Gurvich A, Heckers SH, Frahm J, Nave KA, Ehrenreich H (2012).
A myelin gene causative of a catatonia-depression syndrome upon aging.
EMBO Mol Med. 4, 528-539

Kästner A, Grube S, El-Kordi A, Stepniak B, Friedrichs H, Sargin D, Schwitulla J, Begemann M, Giegling I, Miskowiak KW, Sperling S, Hannke K, Ramin A, Heinrich R, Gefeller O, Nave KA, Rujescu D, Ehrenreich H (2012).
Common variants of the genes encoding erythropoietin and its receptor modulate cognitive performance in schizophrenia.
Mol Med. 18, 1029-1040
 


2011

Wüstenberg T, Begemann M, Bartels C, Gefeller O, Stawicki S, Hinze-Selch D, Mohr A, Falkai P, Aldenhoff JB, Knauth M, Nave KA, Ehrenreich H (2011).
Recombinant human erythropoietin delays loss of gray matter in chronic schizophrenia.
Mol Psychiatry. 16, 26-36

Grube S, Gerchen MF, Adamcio B, Pardo LA, Martin S, Malzahn D, Papiol S, Begemann M, Ribbe K, Friedrichs H, Radyushkin KA, Müller M, Benseler F, Riggert J, Falkai P, Bickeböller H, Nave KA, Brose N, Stühmer W, Ehrenreich H (2011).
A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia.
EMBO Mol Med. 3, 309-319

Sargin D, El-Kordi A, Agarwal A, Muller M, Wojcik SM, Hassouna I, Sperling S, Nave KA, Ehrenreich H (2011).
Expression of constitutively active erythropoietin receptor in cortical neurons boosts higher cognitive functions in mice.
BMC Biol. 9, 27-27

Ribbe K, Ackermann V, Schwitulla J, Begemann M, Papiol S, Grube S, Sperling S, Friedrichs H, Jahn O, Sillaber I, Gefeller O, Krampe H, Ehrenreich H (2011).
Prediction of the Risk of Comorbid Alcoholism in Schizophrenia by Interaction of Common Genetic Variants in the Corticotropin-Releasing Factor System.
Arch Gen Psychiatry. 68, 1247-1256

Papiol S, Malzahn D, Kästner A, Sperling S, Begemann M, Stefansson H, Bickeböller H, Nave K-A and Ehrenreich H (2011). Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia
Translational Psychiatry 1, e45-e45

Treiber H, Hagemeyer N, Ehrenreich H, Simons M (2011).
BACE1 in central nervous system myelination revisited.
Mol Psychiatry. 17, 237-239
 


2010

Begemann M, Grube S, Papiol S, Malzahn D, Krampe H, Ribbe K, Friedrichs H, Radyushkin KA, El-Kordi A, Benseler F, Hannke K, Sperling S, Schwerdtfeger D, Thanhäuser I, Gerchen MF, Ghorbani M, Gutwinski S, Hilmes C, Leppert R, Ronnenberg A, Sowislo J, Stawicki S, Stödtke M, Szuszies C, Reim K, Riggert J, Eckstein F, Falkai P, Bickeböller H, Nave KA, Brose N, Ehrenreich H (2010). Modification of Cognitive Performance in Schizophrenia by Complexin 2 Gene Polymorphisms.
Arch Gen Psychiatry. 67, 879-888

Radyushkin K, El-Kordi A, Boretius S, Castaneda S, Ronnenberg A, Reim K, Bickeböller H, Frahm J, Brose N, Ehrenreich H (2010).
Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia.
Genes Brain Behav. 9, 592-602

Brzózka MM, Radyushkin K, Wichert SP, Ehrenreich H, Rossner MJ (2010).
Cognitive and Sensorimotor Gating Impairments in Transgenic Mice Overexpressing the Schizophrenia Susceptibility Gene Tcf4 in the Brain.
Biol Psychiatry. 68, 33-40
 


2009

Radyushkin K, Hammerschmidt K, Boretius S, Varoqueaux F, El-Kordi A, Ronnenberg A, Winter D, Frahm J, Fischer J, Brose N, Ehrenreich H. (2009).
Neuroligin-3 deficient mice: Model of a monogenic heritable form of autism with an olfactory deficit.
Genes Brain Behav. 8, 416-425

El-Kordi A, Radyushkin K, Ehrenreich H (2009).
Erythropoietin improves operant conditioning and stability of cognitive performance in mice.
BMC Biol. 7, 37-37
 


2008

Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, Varoqueaux F, Ramanantsoa N, Gallego J, Ronnenberg A, Winter D, Frahm J, Fischer J, Bourgeron T, Ehrenreich H, Brose N. (2008).
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.
Proc Natl Acad Sci U S A. 105, 1710-1715

Adamcio B, Sargin D, Stradomska A, Medrihan L, Gertler C, Theis F, Zhang M, Muller M, Hassouna I, Hannke K, Sperling S, Radyushkin K, El-Kordi A, Schulze L, Ronnenberg A, Wolf F, Brose N, Rhee JS, Zhang W, Ehrenreich H (2008).
Erythropoietin enhances hippocampal long-term potentiation and memory.
BMC Biol. 6, 37-

Sargin D, Hassouna I, Sperling S, Sirén AL, Ehrenreich H (2008).
Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion.
Glia 57, 693-702

Brinkmann BG, Agarwal A, Sereda MW, Garratt AN, Müller T, Wende H, Stassart RM, Nawaz S, Humml C, Velanac V, Radyushkin K, Goebbels S, Fischer TM, Franklin RJ, Lai C, Ehrenreich H, Birchmeier C, Schwab MH, Nave KA (2008).
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Neuron 59, 581-595
 


2007

Ehrenreich H, Hinze-Selch D, Stawicki S, Aust C, Knolle-Veentjer S, Wilms S, Heinz G, Erdag S, Jahn H, Degner D, Ritzen M, Mohr A, Wagner M, Schneider U, Bohn M, Huber M, Czernik A, Pollmächer T, Maier W, Sirén AL, Klosterkötter J, Falkai P, Rüther E, Aldenhoff JB, Krampe H. (2007).
Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin.
Mol Psychiatry. 12, 206-220

Ehrenreich H, Fischer B, Norra C, Schellenberger F, Stiefel M, Sirén AL, Paulus W, Nave KA, Gold R, Bartels C (2007).
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis.
Brain 130, 2577-2588
 

Nave KA, Sereda MW, Ehrenreich H (2007).
Mechanisms of disease: inherited demyelinating neuropathies-from basic to clinical research.
Nat Clin Pract Neurol. 8, 453-464
 


2006

Sirén, A.L., Radyushkin, K., Boretius, S., Kämmer, D., Riechers, C.C., Natt, O., Sargin, D., Watanabe, T., Sperling, S., Michaelis, T., Price, J., Meyer, B., Frahm, J., Ehrenreich, H. (2006).
Global brain atrophy after unilateral parietal lesion and its prevention by erythropoietin
Brain 129, 480-489
 


- 2005

Ehrenreich, H., Hasselblatt, M., Knerlich, F., von Ahsen, N., Jacob, S., Sperling, S., Woldt, H., Vehmeyer, K., Nave, K.-A., Sirén, A.-L. (2005).
A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain
Proc Natl Acad Sci U S A. 102, 862-867

Ehrenreich, H. (2004).
A boost for translational neuroscience
Science 305, 184-185

Ehrenreich, H., Degner, D., Meller, J., Brines, M., Behe, M., Hasselblatt, M., Woldt, H., Falkai, P., Knerlich, F., Jacob, S., von Ahsen, N., Maier, W., Bruck, W., Rüther, E., Cerami, A., Becker, W., Sirén, A.-L. (2004).
Erythropoietin: a candidate compound for neuroprotection in schizophrenia
Mol Psychiatry. 9, 42-54

Sirén AL, Fratelli M, Brines M, Goemans C, Casagrande S, Lewczuk P, Keenan S, Gleiter C, Pasquali C, Capobianco A, Mennini T, Heumann R, Cerami A, Ehrenreich H, Ghezzi P (2001).
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress.
Proc Natl Acad Sci U S A. 98, 4044-4049

Ehrenreich H, Anderson RW, Fox CH, Rieckmann P, Hoffman GS, Travis WD, Coligan JE, Kehrl JH, Fauci AS (1990).
Endothelins, peptides with potent vasoactive properties, are produced by human macrophages.
J Exp Med. 172, 1741-1748

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