Publikationen von C. L. Will
Alle Typen
Zeitschriftenartikel (66)
21.
Zeitschriftenartikel
7, 11997 (2016)
A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. Nature Communications 22.
Zeitschriftenartikel
22 (2), S. 265 - 277 (2016)
Multiple protein-protein interactions converging on the Prp38 protein during activation of the human spliceosome. RNA 23.
Zeitschriftenartikel
59 (22), S. 10190 - 10197 (2016)
Rational design of cyclic peptide inhibitors of U2AF homology motif (UHM) domains to modulate pre-mRNA splicing. Journal of Medicinal Chemistry 24.
Zeitschriftenartikel
21 (11), S. 1993 - 2005 (2015)
Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 25.
Zeitschriftenartikel
22 (2), S. 138 - 144 (2015)
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 26.
Zeitschriftenartikel
11 (4), S. 298 - 312 (2014)
Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology 27.
Zeitschriftenartikel
8 (9), e74851 (2013)
The Prp19 complex directly functions in mitotic spindle assembly. PLoS One 28.
Zeitschriftenartikel
341 (6141), S. 80 - 84 (2013)
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science 29.
Zeitschriftenartikel
26 (23), S. 2422 - 2434 (2012)
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes and Development 30.
Zeitschriftenartikel
3, 994 (2012)
Retention of posttranscriptional spliceosomes in nuclear speckles until splicing completion. Nature communications 31.
Zeitschriftenartikel
45 (4), S. 567 - 580 (2012)
Dynamic protein-protein interaction wiring of the human spliceosome. Molecular Cell 32.
Zeitschriftenartikel
31 (13), S. 2667 - 2682 (2011)
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Molecular and Cellular Biology 33.
Zeitschriftenartikel
331 (6018), S. 760 - 764 (2011)
HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science 34.
Zeitschriftenartikel
16 (12), S. 2384 - 2403 (2010)
Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA 35.
Zeitschriftenartikel
30 (9), S. 2105 - 2119 (2010)
Molecular architecture of the human Prp19/CDC5L complex. Molecular and Cellular Biology 36.
Zeitschriftenartikel
38 (2), S. 223 - 235 (2010)
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Molecular Cell 37.
Zeitschriftenartikel
37 (6), S. 821 - 833 (2010)
An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing. Molecular Cell 38.
Zeitschriftenartikel
17 (2), S. 216 - 222 (2010)
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nature Structural and Molecular Biology 39.
Zeitschriftenartikel
136 (4), S. 701 - 718 (2009)
The spliceosome: design principles of a dynamic RNP machine. Cell 40.
Zeitschriftenartikel
29 (1), S. 281 - 301 (2009)
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Molecular and Cellular Biology