Publikationen von R. Lührmann
Alle Typen
Zeitschriftenartikel (189)
61.
Zeitschriftenartikel
27 (4), S. 413 - 428 (2013)
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes and Development 62.
Zeitschriftenartikel
26 (23), S. 2422 - 2434 (2012)
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes and Development 63.
Zeitschriftenartikel
109 (43), S. 17418 - 17423 (2012)
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proceedings of the National Academy of Sciences of the United States of America 64.
Zeitschriftenartikel
18 (9), S. 1605 - 1611 (2012)
Molecular architecture of Zinc chelating small molecules that inhibit spliceosome assembly at an early stage. RNA 65.
Zeitschriftenartikel
3, 994 (2012)
Retention of posttranscriptional spliceosomes in nuclear speckles until splicing completion. Nature communications 66.
Zeitschriftenartikel
18 (7), S. 1347 - 1357 (2012)
Antisense-targeted immuno-EM localization of the pre-mRNA path in the spliceosomal C complex. RNA 67.
Zeitschriftenartikel
31 (6), S. 1591 - 1604 (2012)
Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO Journal 68.
Zeitschriftenartikel
13 (5), S. 640 - 644 (2012)
Psoromic acid derivatives: A new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay. ChemBioChem 69.
Zeitschriftenartikel
45 (4), S. 567 - 580 (2012)
Dynamic protein-protein interaction wiring of the human spliceosome. Molecular Cell 70.
Zeitschriftenartikel
18 (6), S. 1244 - 1256 (2012)
Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 71.
Zeitschriftenartikel
31 (9), S. 2222 - 2234 (2012)
Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO Journal 72.
Zeitschriftenartikel
17 (9), S. 1655 - 1663 (2011)
Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31. RNA 73.
Zeitschriftenartikel
31 (13), S. 2667 - 2682 (2011)
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Molecular and Cellular Biology 74.
Zeitschriftenartikel
286 (12), S. 10126 - 10136 (2011)
Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. Journal of Biological Chemistry 75.
Zeitschriftenartikel
331 (6018), S. 760 - 764 (2011)
HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science 76.
Zeitschriftenartikel
40 (6), S. 927 - 938 (2010)
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core. Molecular Cell 77.
Zeitschriftenartikel
16 (12), S. 2384 - 2403 (2010)
Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA 78.
Zeitschriftenartikel
18 (6), S. 667 - 676 (2010)
An approach for de novo structure determination of dynamic molecular assemblies by electron cryomicroscopy. Structure 79.
Zeitschriftenartikel
30 (9), S. 2105 - 2119 (2010)
Molecular architecture of the human Prp19/CDC5L complex. Molecular and Cellular Biology 80.
Zeitschriftenartikel
38 (2), S. 223 - 235 (2010)
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Molecular Cell