Zeitschriftenartikel (690)

101.
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Aillaud, I.; Kaniyappan, S.; Chandupatla, R. R.; Ramirez, L. M.; Alkhashrom, S.; Eichler, J.; Horn, A. H. C.; Zweckstetter, M.; Mandelkow, E.-M.; Sticht, H. et al.; Funke, S. A.: A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro. Alzheimer's Research & Therapy 14, 15 (2022)
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102.
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Chakrabarti, K. S.; Olsson, S.; Pratihar, S.; Giller, K.; Overkamp, K.; Lee, K. O.; Gapsys, V.; Ryu, K.-S.; de Groot, B. L.; Noé, F. et al.; Becker, S.; Lee, D.; Weikl, T. R.; Griesinger, C.: A litmus test for classifying recognition mechanisms of transiently binding proteins. Nature Communications 13, 3792 (2022)
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103.
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Le Marchand, T.; Schubeis, T.; Bonaccorsi, M.; Paluch, P.; Lalli, D.; Pell, A. J.; Andreas, L. B.; Jaudzems, K.; Stanek, J.; Pintacuda, G.: 1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning. Chemical Reviews 122 (10), S. 9943 - 10018 (2022)
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104.
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Moll, A.; Ramirez, L. M.; Ninov, M.; Schwarz, J.; Urlaub, H.; Zweckstetter, M.: Hsp multichaperone complex buffers pathologically modified Tau. Nature Communications 13, 3668 (2022)
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105.
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Bodenhausen, G.; Ernst, M.; Griesinger, C.; Keller, T.; Kessler, H.; Meier, B.; Wokaun, A.: Richard Ernst (1933–2021). Angewandte Chemie International Edition 60 (45), S. 23944 - 23945 (2021)
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106.
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Dauer née Joppe, K.; Tatenhorst, L.; Caldi Gomes, L.; Zhang, S.; Parvaz, M.; Carboni, E.; Roser, A.-E.; El DeBakey, H.; Bähr, M.; Vogel-Mikuš, K. et al.; Ip, C. W.; Becker, S.; Zweckstetter, M.; Lingor, P.: Brain iron enrichment attenuates α-synuclein spreading after injection of preformed fibrils. Journal of Neurochemistry 159 (3), S. 554 - 573 (2021)
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107.
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Vemulapalli, S. P.; Becker, S.; Griesinger, C.; Rezaei-Ghaleh, N.: Combined high-pressure and multiquantum NMR and molecular simulation propose a role for N-terminal salt bridges in amyloid-beta. The Journal of Physical Chemistry Letters 12 (40), S. 9933 - 9939 (2021)
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108.
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Mese, K.; Bunz, O.; Volkwein, W.; Vemulapalli, S. P.; Zhang, W. L.; Schellhorn, S.; Heenemann, K.; Rueckner, A.; Sing, A.; Vahlenkamp, T.W. et al.; Severing, A. L.; Gao, J.; Aydin, M.; Jung, D.; Bachmann, H. S.; Zanker, K. S.; Busch, U.; Baiker, A.; Griesinger, C.; Griesinger, C.; Ehrhardt, A.: Enhanced antiviral function of magnesium chloride-modified Heparin on a broad spectrum of viruses. Journal of Molecular Sciences 22 (18), 10075 (2021)
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109.
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Korchak, S.; Kaltschnee, L.; Dervisoglu, R.; Andreas, L. B.; Griesinger, C.; Glöggler, S.: Spontaneous enhancement of magnetic resonance signals using a RASER. Angewandte Chemie International Edition 60 (38), S. 20984 - 20990 (2021)
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110.
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Vemulapalli, S. P.; Fuentes-Monteverde, J. C.; Karschin, N.; Oji, T.; Griesinger, C.; Wolkenstein, K.: Structure and absolute configuration of phenanthro-perylene quinone pigments from the deep-sea crinoid Hypalocrinus naresianus. Marine Drugs 19 (8), 445 (2021)
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111.
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Martinez Hernandez, A.; Silbern, I.; Geffers, I.; Tatenhorst, L.; Becker, S.; Urlaub, H.; Zweckstetter, M.; Griesinger, C.; Eichele, G.: Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 15, 643391 (2021)
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112.
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Babu, M.; Favretto, F.; Ibáñez de Opakua, A.; Rankovic, M.; Becker, S.; Zweckstetter, M.: Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis. Nature Communications 12, 3396 (2021)
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113.
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Kuebler, L.; Buss, S.; Leonov, A.; Ryazanov, S.; Schmidt, F.; Maurer, A.; Weckbecker, D.; Landau, A. M.; Lillethorup, T. P.; Bleher, D. et al.; Saw, R. S.; Pichler, B. J.; Griesinger, C.; Giese, A.; Herfert, C.: [11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates. European Journal of Nuclear Medicine and Molecular Imaging 48 (6), S. 1759 - 1772 (2021)
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114.
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Nimerovsky, E.; Tekwani Movellan, K.; Zhang, X. C.; Forster, M. C.; Najbauer, E.; Xue, K.; Dervisoglu, R.; Giller, K.; Griesinger, C.; Becker, S. et al.; Andreas, L. B.: Proton detected solid-state NMR of membrane proteins at 28 Tesla (1.2 GHz) and 100 kHz magic-angle spinning. Biomolecules 11 (5), 752 (2021)
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115.
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Antonschmidt, L.; Dervisoglu, R.; Sant, V.; Tekwani Movellan, K.; Mey, I.; Riedel, D.; Steinem, C.; Becker, S.; Andreas, L. B.; Griesinger, C.: Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes. Science Advances 7 (20), eabg2174 (2021)
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116.
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Najbauer, E.; Becker, S.; Giller, K.; Zweckstetter, M.; Lange, A.; Steinem, C.; de Groot, B. L.; Griesinger, C.; Andreas, L. B.: Structure, gating and interactions of the voltage-dependent anion channel. European Biophysics Journal 50 (2), S. 159 - 172 (2021)
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117.
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Rivière, G.; Jaipuria, G.; Andreas, L. B.; Leonov, A.; Giller, K.; Becker, S.; Zweckstetter, M.: Membrane-embedded TSPO: an NMR view. European Biophysics Journal 50 (2), S. 173 - 180 (2021)
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118.
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Liu, H.; Koros, C.; Strohäker, T.; Schulte, C.; Bozi, M.; Varvaresos, S.; de Opakua, A. I.; Simitsi, A. M.; Bougea, A.; Voumvourakis, K. et al.; Maniati, M.; Papageorgiou, S. G.; Hauser, A.‐.; Becker, S.; Zweckstetter, M.; Stefanis, L.; Gasser, T.: A novel SNCA A30G mutation causes familial Parkinsonʼs disease. Movement Disorders, In Press (2021)
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119.
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Schlauersbach, J.; Hanio, S.; Lenz, B.; Vemulapalli, S. P.; Griesinger, C.; Pöppler, A.-C.; Harlacher, C.; Galli, B.; Meinel, L.: Leveraging bile solubilization of poorly water-soluble drugs by rational polymer selection. Journal of Controlled Release 330, S. 36 - 48 (2021)
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120.
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Sieger, A.; Rankovic, M.; Favretto, F.; Ukmar‐Godec, T.; Strohäker, T.; Becker, S.; Zweckstetter, M.: Interplay between tau and α‐synuclein liquid–liquid phase separation. Protein Science, In Press (2021)
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121.
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Stopp, M.; Steinmetz, P. A.; Schubert, C.; Griesinger, C.; Schneider, D.; Unden, G.: Transmembrane signaling and cytoplasmic signal conversion by dimeric transmembrane helix 2 and a linker domain of the DcuS sensor kinase. Journal of Biological Chemistry 296 (1), 100148 (2021)
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122.
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Favretto, F.; Flores, D.; Baker, J. D.; Strohäker, T.; Andreas, L. B.; Blair, L. J.; Becker, S.; Zweckstetter, M.: Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war. Nature Communications 11, 6046 (2020)
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123.
Zeitschriftenartikel
Dominguez-Meijide, A.; Vasili, E.; König, A.; Cima-Omori, M.-S.; Ibáñez de Opakua, A.; Leonov, A.; Ryazanov, S.; Zweckstetter, M.; Griesinger, C.; Outeiro, T. F.: Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization. Scientific Reports 10, 12827 (2020)
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124.
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Gerdes, C.; Waal, N.; Offner, T.; Fornasiero, E. F.; Wender, N.; Verbarg, H.; Manzini, I.; Trenkwalder, C.; Mollenhauer, B.; Strohäker, T. et al.; Zweckstetter, M.; Becker, S.; Rizzoli, S. O.; Basmanav, F. B.; Opazo, F.: A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol. Nature Communications 11, 2729 (2020)
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125.
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Dobrev, P.; Vemulapalli, S. P.; Nath, N.; Griesinger, C.; Grubmüller, H.: Probing the accuracy of explicit solvent constant pH molecular dynamics simulations for peptides. Journal of Chemical Theory and Computation 16 (4), S. 2561 - 2569 (2020)
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126.
Zeitschriftenartikel
Favretto, F.; Baker, J.; Strohäker, T.; Andreas, L.; Blair, L.; Becker, S.; Zweckstetter, M.: Molecular basis of the interaction of cyclophilin A with alpha-synuclein. Angewandte Chemie International Edition 132 (14), S. 5692 - 5695 (2020)
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127.
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Maurer, A.; Leonov, A.; Ryazanov, S.; Herfert, K.; Kuebler, L.; Buss, S.; Schmidt, F.; Weckbecker, D.; Linder, R.; Bender, D. et al.; Giese, A.; Pichler, B. J.; Griesinger, C.: 11 C radiolabeling of anle253b: A putative PET tracer for Parkinson's disease that binds to α-synuclein fibrils in vitro and crosses the blood-brain barrier. ChemMedChem 15 (5), S. 411 - 415 (2020)
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128.
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Mamone, S.; Rezaei-Ghaleh, N.; Opazo, F.; Griesinger, C.; Glöggler, S.: Singlet-filtered NMR spectroscopy. Science Advances 6 (8), eaaz1955 (2020)
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129.
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Liu, P.; Pang, B.; Dechert, S.; Zhang, X.; Andreas, L.; Fischer, S.; Meyer, F.; Zhang, K.: Structure selectivity of universal alkaline periodate oxidation on lignocellulose for facile isolation of cellulose nanocrystals. Angewandte Chemie International Edition 59 (8), S. 3218 - 3225 (2020)
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130.
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Wong, L. E.; Bhatt, A.; Erdmann, P. S.; Hou, Z.; Maier, J.; Pirkuliyeva, S.; Engelke, M.; Becker, S.; Plitzko, J.; Wienands, J. et al.; Griesinger, C.: Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness. Nature Communications 11, 848 (2020)
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131.
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Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F.; Leonov, A.; Ryazanov, S.; Griesinger, C.; Giese, A. et al.; Cauchi, R. J.; Vassallo, N.: Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin. Biochimica et Biophysica Acta. Biomembranes 1862 (2), 183064 (2020)
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132.
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Tekwani Movellan, K.; Wegstroth, M.; Overkamp, K.; Leonov, A.; Becker, S.; Andreas, L. B.: Imidazole-imidazole hydrogen bonding in the pH-sensing histidine side chains of influenza A M2. Journal of the American Chemical Society 142 (6), S. 2704 - 2708 (2020)
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133.
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Smith, C. A.; Mazur, A.; Rout, A. K.; Becker, S.; Lee, D.; de Groot, B. L.; Griesinger, C.: Enhancing NMR derived ensembles with kinetics on multiple timescales. Journal of Biomolecular NMR 74 (1), S. 27 - 43 (2020)
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134.
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Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Nicolai, J.; Praest, P.; Giese, A.; Winter, R.; Khemtemourian, L.; Griesinger, C.; Killian, J. A.: The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers. Scientific Reports 9 (1), 19023 (2019)
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135.
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Strohäker, T.; Jung, B. C.; Liou, S. H.; Fernandez, C. O.; Riedel, D.; Becker, S.; Halliday, G. M.; Bennati, M.; Kim, W. S.; Lee, S. J. et al.; Zweckstetter, M.: Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts. Nature Communications 10, 5535 (2019)
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136.
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Cukierman, D. S.; Bodnar, N.; Evangelista, B. N.; Nagy, L.; Kllay, C.; Rey, N. A.: Impact of pyridine-2-carboxaldehyde-derived aroylhydrazones on the copper-catalyzed oxidation of the M112A PrP103-112 mutant fragment. Journal of Biological Inorganic Chemistry 24 (8), S. 1231 - 1244 (2019)
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137.
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González, N.; Gentile, I.; Garro, H. A.; Delgado-Ocaña, S.; Ramunno, C. F.; Buratti, F. A.; Griesinger, C.; Fernandez, C. O.: Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: A structural and cell-based study. Journal of Biological Inorganic Chemistry 24 (8), S. 1269 - 1278 (2019)
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138.
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de Melo Sousa, C. M.; Giordani, R. B.; de Almeida, W. A. M.; Griesinger, C.; Gil, R. R.; Navarro‐Vázquez, A.; Hallwass, F.: Effect of the solvent on the conformation of monocrotaline as determined by isotropic and anisotropic NMR parameters. Magnetic Resonance in Chemistry, (in press) (2019)
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139.
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Rezaei-Ghaleh, N.; Munari, F.; Becker, S.; Assfalg, M.; Griesinger, C.: A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media. Chemical Communications 55 (82), S. 12404 - 12407 (2019)
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140.
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Wegrzynowicz, M.; Bar-On, D.; Calo’, L.; Anichtchik, O.; Iovino, M.; Xia, J.; Ryazanov, S.; Leonov, A.; Giese, A.; Dalley, J. W. et al.; Griesinger, C.; Ashery, U.; Spillantini, M. G.: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica 138 (4), S. 575 - 595 (2019)
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141.
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Gonzalez, N.; Arcos-Lopez, T.; König, A.; Quintanar, L.; Marquez, M. M.; Outeiro, T. F.; Fernandez, C. O.: Effects of alpha-synuclein post-translational modifications on metal binding. Journal of Neurochemistry 150 (5), S. 507 - 521 (2019)
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142.
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González, N.; Arcos‐López, T.; König, A.; Quintanar, L.; Márquez, M. M.; Outeiro, T. F.; Fernandez, C. O.: Effects of alpha-synuclein posttranslational modifications on metal binding. Journal of Neurochemistry 150 (5), S. 507 - 521 (2019)
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143.
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Mavroeidi, P.; Arvanitaki, F.; Karakitsou, A. K.; Vetsi, M.; Kloukina, I.; Zweckstetter, M.; Giller, K.; Becker, S.; Sorrentino, Z. A.; Giasson, B. I. et al.; Jensen, P. H.; Stefanis, L.; Xilouri, M.: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica 138 (3), S. 415 - 441 (2019)
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144.
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Kaltschnee, L.; Jagtap, A.; McCormick, J.; Wagner, S.; Bouchard, L. S.; Utz, M.; Griesinger, C.; Glöggler, S.: Hyperpolarization of amino acids in water utilizing parahydrogen on a rhodium nanocatalyst. Chemistry - A European Journal 25 (47), S. 11031 - 11035 (2019)
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145.
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Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C.; Becker, S.; S: Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 5 (8), eaaw4988 (2019)
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146.
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Brendel, M.; Deussing, M.; Blume, T.; Kaiser, L.; Probst, F.; Overhoff, F.; Peters, F.; von Ungern-Sternberg, B.; Ryazanov, S.; Leonov, A. et al.; Griesinger, C.; Zwergal, A.; Levin, J.; Bartenstein, P.; Yakushev, I.; Cumming, P.; Boening, G.; Ziegler, S.; Herms, J.; Giese, A.; Rominger, A.: Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research and Therapy 11 (1), 67 (2019)
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147.
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Hwang, S.; Öster, C.; Chevelkov, V.; Giller, K.; Lange, S.; Becker, S.; Lange, A.: Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations. Journal of Biomolecular NMR 73 (6-7), S. 281 - 291 (2019)
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148.
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Bartels, M.; Weckbecker, D.; Kuhn, P. H.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Lichtenthaler, S. F.; Bötzel, K.; Giese, A.: Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Scientific Reports 9, 9100 (2019)
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149.
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Gong, J.; Szego, E. M.; Leonov, A.; Benito, E.; Becker, S.; Fischer, A.; Zweckstetter, M.; Outeiro, T.; Schneider, A.: Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 39 (19), S. 3752 - 3769 (2019)
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150.
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Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18), S. 8699 - 8708 (2019)
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