Publikationen von Patrick Cramer

Velychko, T.; Mohammad, E.; Ferrer-Vicens, I.; Parfentev, I.; Werner, M.; Studniarek, C.; Schwalb, B.; Urlaub, H.; Murphy, S.; Cramer, P. et al.; Lidschreiber, M.: CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release. Molecular Cell (2024)

Žumer, K.; Ochmann, M.; Aljahani, A.; Zheenbekova, A.; Devadas, A.; Maier, K. C.; Rus, P.; Neef, U.; Oudelaar, A. M.; Cramer, P.: FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo. Molecular Cell (2024)

Patil, S.; Cremosnik, G.; Dötsch, L.; Flegel, J.; Schulte, B.; Maier, K. C.; Žumer, K.; Cramer, P.; Janning, P.; Sievers, S. et al.; Ziegler, S.; Waldmann, H.: Tafbromin selectively targets the TAF1 bromodomain. Angewandte Chemie International Edition (2024)

Zhan, Y.; Grabbe, F.; Oberbeckmann, E.; Dienemann, C.; Cramer, P.: Three-step mechanism of promoter escape by RNA polymerase II. Molecular Cell 84 (9), S. 1699 - 1710.e6 (2024)

Fianu, I.; Ochmann, M.; Walshe, J. L.; Dybkov, O.; Cruz, J. N.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-dependent RNA polymerase II termination. Nature (2024)

Cramer, P.: Good reasons for structural biology. Nature Structural & Molecular Biology 31, S. 393 - 394 (2024)

Kokic, G.; Yakoub, G.; van den Heuvel, D.; Wondergem, A. P.; van der Meer, P. J.; van der Weegen, Y.; Chernev, A.; Fianu, I.; Fokkens, T. J.; Lorenz, S. et al.; Urlaub, H.; Cramer, P.; Luijsterburg, M. S.: Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nature Structural & Molecular Biology 31, S. 536 - 547 (2024)

Oberbeckmann, E.; Quililan, K.; Cramer, P.; Oudelaar, A. M.: In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization. Nature Genetics 56, S. 483 - 492 (2024)

Chen, Y.; Cramer, P.: RNA polymerase II elongation factors use conserved regulatory mechanisms. Current Opinion in Structural Biology 84, 102766 (2024)

Sun, Y.; Wiese, M.; Hmadi, R.; Karayol, R.; Seyfferth, J.; Martinez Greene, J.A.; Erdogdu, N.U.; Deboutte, W.; Arrigoni, L.; Holz, H. et al.; Renschler, G.; Hirsch, N.; Foertsch, A.; Basilicata, M.F.; Stehle, T.; Shvedunova, M.; Bella, C.; Pessoa Rodrigues, C.; Schwalb, B.; Cramer, P.; Manke, T.; Akhtar, A.: MSL2 ensures biallelic gene expression in mammals. Nature 624 (7990), S. 173 - 181 (2023)

Chen, Y.; Kokic, G.; Dienemann, C.; Dybkov, O.; Urlaub, H.; Cramer, P.: Structure of the transcribing RNA polymerase II–Elongin complex. Nature Structural & Molecular Biology 30, S. 1925 - 1935 (2023)

Palau, A.; Segerberg, F.; Lidschreiber, M.; Lidschreiber, K.; Naughton, A.J.; Needhamsen, M.; Jung, L.A.; Jagodic, M.; Cramer, P.; Lehmann, S. et al.; Carlsten, M.; Lennartsson, A.: Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells. Leukemia 37, S. 1830 - 1841 (2023)

Garg, G.; Dienemann, C.; Farnung, L.; Schwarz, J.; Linden, A.; Urlaub, H.; Cramer, P.: Structural insights into human co-transcriptional capping. Molecular Cell 83 (14), S. 2464 - 2477.e5 (2023)

Rouvière, J. O.; Salerno-Kochan, A.; Lykke-Andersen, S.; Garland, W.; Dou, Y.; Rathore, O.; Molska, E. Š.; Wu, G.; Schmid, M.; Bugai, A. et al.; Jakobsen, L.; Zumer, K.; Cramer, P.; Andersen, J. S.; Conti, E.; Jensen, T. H.: ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. Molecular Cell 83 (13), S. 2240 - 2257 (2023)

Abril-Garrido, J.; Dienemann, C.; Grabbe, F.; Velychko, T.; Lidschreiber, M.; Wang, H.; Cramer, P.: Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 83 (11), S. 1798 - 1809.e7 (2023)

Rengachari, S.; Schilbach, S.; Cramer, P.: Mediator structure and function in transcription initiation. Biological Chemistry, aop (2023)

Schilbach, S.; Wang, H.; Dienemann, C.; Cramer, P.: Yeast PIC-mediator structure with RNA polymerase II C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 120 (15), e2220542120 (2023)

Wang, H.; Schilbach, S.; Ninov, M.; Urlaub, H.; Cramer, P.: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nature Structural and Molecular Biology 30, S. 226 - 232 (2023)

Flores-Solis, D.; Lushpinskaia, I.P.; Polyansky, A.A.; Changiarath, A.; Boehning, M.; Mirkovic, M.; Walshe, J.; Pietrek, L.M.; Cramer, P.; Stelzl, L.S. et al.; Zagrovic, B.; Zweckstetter, M.: Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II. Nature Communications 14 (1), 5979 (2023)

Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.; Urlaub, H.; Dienemann, C.; Vannini, A.; Cramer, P.: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 29, S. 1159 - 1169 (2022)