Publikationen von Ashwin Chari
Alle Typen
Zeitschriftenartikel (43)
Zeitschriftenartikel
15 (1), 1147 (2024)
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications
Zeitschriftenartikel
15, 411 (2024)
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design. Nature Communications
Zeitschriftenartikel
52, S. 391 - 411 (2023)
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy. Annual Review of Biophysics
Zeitschriftenartikel
EIGER2 hybrid-photon-counting X-ray detectors for advanced synchrotron diffraction experiments. Journal of Synchrotron Radiation, S. 723 - 738 (2023)
Zeitschriftenartikel
186 (23), e16, S. 5054 - 5067 (2023)
Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots. Cell
Zeitschriftenartikel
50 (9), S. 5282 - 5298 (2022)
Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research
Zeitschriftenartikel
11, 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life
Zeitschriftenartikel
11 (12), 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life
Zeitschriftenartikel
587 (7832), S. 157 - 161 (2020)
Atomic-resolution protein structure determination by cryo-EM. Nature
Zeitschriftenartikel
6 (30), eaba3916 (2020)
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances
Zeitschriftenartikel
180 (6), S. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell
Zeitschriftenartikel
27 (7), S. 1124 - 1136 (2019)
Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure
Zeitschriftenartikel
17 (7), S. 471 - 492 (2018)
Cryo-EM in drug discovery: Achievements, limitations and prospects. Nature Reviews Drug Discovery
Zeitschriftenartikel
8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications
Zeitschriftenartikel
353 (6306), S. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science
Zeitschriftenartikel
16 (12), S. 3103 - 3112 (2016)
The ribosome cooperates with the assembly chaperone pICln to initiate formation of snRNPs. Cell Reports
Zeitschriftenartikel
353 (6299), S. 594 - 598 (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science
Zeitschriftenartikel
65 (1), S. 23 - 34 (2016)
Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy. Microscopy
Zeitschriftenartikel
12 (9), S. 859 - 865 (2015)
ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods
Zeitschriftenartikel
34 (14), S. 1925 - 1941 (2015)
Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization. EMBO Journal