Publications of Gesine Saher

Journal Article (31)

Journal Article
Paul, D.; Hoppe, S.; Saher, G.; Krijnse-Locker, J.; Bartenschlager, R.: Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment. Journal of Virology 87 (19), pp. 10612 - 10627 (2013)
Journal Article
Saher, G.; Rudolphi, F.; Corthals, K.; Ruhwedel, T.; Schmidt, K.-F.; Löwel, S.; Dibaj, P.; Barrette, B.; Möbius, W.; Nave, K.-A.: Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet. Nature Medicine 18 (7), pp. 1130 - 1135 (2012)
Journal Article
Fünfschilling, U.; Jockusch, W. J.; Sivakumar, N.; Möbius, W.; Corthals, K.; Li, S.; Quintes, S.; Kim, Y.; Schaap, I. A. T.; Rhee, J.-S. et al.; Nave, K.-A.; Saher, G.: Critical time window of neuronal cholesterol synthesis during neurite outgrowth. The Journal of Neuroscience 32 (22), pp. 7632 - 7645 (2012)
Journal Article
Chrast, R.; Saher, G.; Nave, K.-A.; Verheijen, M. H. G.: Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models. Journal of Lipid Research 52 (3), pp. 419 - 434 (2011)
Journal Article
Kassmann, C. M.; Quintes, S.; Rietdorf, J.; Möbius, W.; Sereda, M. W.; Nientiedt, T.; Saher, G.; Baes, M.; Nave, K.-A.: A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity. FEBS Letters 585 (14), pp. 2205 - 2211 (2011)
Journal Article
Saher, G.; Quintes, S.; Nave, K.-A.: Cholesterol: a novel regulatory role in myelin formation. The Neuroscientist 17 (1), pp. 79 - 93 (2011)
Journal Article
Quintes, S.; Goebbels, S.; Saher, G.; Schwab, M. H.; Nave, K.-A.: Neuron-glia signaling and the protection of axon function by Schwann cells. Journal of the Peripheral Nervous System 15 (1), pp. 10 - 16 (2010)
Journal Article
Saito, K.; Dubreuil, V.; Arai, Y.; Wilsch-Bräuninger, M.; Schwudke, D.; Saher, G.; Miyata, T.; Breier, G.; Thiele, C.; Shevchenko, A. et al.; Nave, K.-A.; Huttner, W. B.: Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proceedings of the National Academy of Sciences of the United States of America 106 (20), pp. 8350 - 8355 (2009)
Journal Article
Saher, G.; Quintes, S.; Möbius, W.; Wehr, M. C.; Krämer-Albers, E.-M.; Brügger, B.; Nave, K.-A.: Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction. The Journal of Neuroscience 29 (19), pp. 6094 - 6104 (2009)
Journal Article
Fünfschilling, U.; Saher, G.; Xiao, L.; Möbius, W.; Nave, K.-A.: Survival of adult neurons lacking cholesterol synthesis in vivo. BMC Neuroscience 8, 1 (2007)
Journal Article
Saher, G.; Brügger, B.; Lappe-Siefke, C.; Möbius, W.; Tozawa, R.-i.; Wehr, M. C.; Wieland, F.; Ishibashi, S.; Nave, K.-A.: High cholesterol level is essential for myelin membrane growth. Nature Neuroscience 8 (4), pp. 468 - 475 (2005)

Book Chapter (1)

Book Chapter
Saher, G.; Simons, M.: Cholesterol and myelin biogenesis. In: Cholesterol Binding and Cholesterol Transport Proteins: Structure and Function in Health and Disease, 10.1007/978-90-481-8622-8_18, pp. 489 - 508 (Ed. Harris, J. R.). Springer, Dordrecht (2010)

Preprint (2)

Depp, C.; Sun, T.; Sasmita, A. O.; Spieth, L.; Berghoff, S. A.; Steixner-Kumar, A. A.; Subramanian, S.; Möbius, W.; Göbbels, S.; Saher, G. et al.; Zampar, S.; Wirths, O.; Thalmann, M.; Saito, T.; Saido, T.; Krüger-Burg, D. D.; Kawaguchi, R.; Willem, M.; Haass, C.; Geschwind, D.; Ehrenreich, H.; Stassart, R.; Nave, K.-A.: Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer's disease. (2021)
Altas, B.; Ju, A.; Cruces Solís, H.; Karaca, S.; Winchenbach, J.; Kaplan, Ö.; Schwark, M.; Wieser, G. L.; Chaugule, V. K.; Majoul, I. et al.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Urlaub, H.; Jahn, O.; Saher, G.; Rhee, J. S.; Kawabe, H.: Physiological and pathophysiological homeostasis of astroglial channel proteins by Nedd4-2. (2019)
Go to Editor View