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Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 152.
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A trap mutant reveals the physiological client spectrum of TRC40. Journal of Cerll Science, (in press) (2019)
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Hypoxia-induced changes in SUMO conjugation affect transcriptional regulation under low oxygen. Molecular and Cellular Proteomics 154.
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Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 155.
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Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 156.
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9 (1), 4188 (2019)
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Scientific Reports 157.
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216 (3), 704 (2019)
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. Journal of Experimental Medicine 158.
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218 (2), 598 (2019)
ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 159.
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The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 160.
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13 (3), 1800083 (2019)
Proteome profiling by label‐free mass spectrometry reveals differentiated response of Campylobacter jejuni 81–176 to sublethal concentrations of bile acids. Proteomics 161.
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10, 2572 (2019)
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 162.
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4 (1), S. 89 - 96 (2019)
Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiology 163.
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25 (13), S. 3618 - 3630 (2018)
Plk1/Polo phosphorylates Sas-4 at the onset of mitosis for an efficient recruitment of pericentriolar material to centrosomes. Cell Reports 164.
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9, 5383 (2018)
RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes. Nature Communications 165.
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46 (22), S. 12109 - 12125 (2018)
Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Research 166.
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Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. The EMBO Journal, In press (e99876) (2018)
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The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 168.
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9, 4532 (2018)
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 169.
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9, 4234 (2018)
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 170.
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9, 4230 (2018)
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nature Communications 171.
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46 (16), S. 8471 - 8482 (2018)
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Research 172.
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13, S. 26 - 38 (2018)
Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. Journal of Clinical and Translational Endocrinology 173.
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10 (9), e8428 (2018)
Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. EMBO Molecular Medicine 174.
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560 (7720), S. 607 - 612 (2018)
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 175.
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Structure of paused transcription complex Pol II–DSIF–NELF. Nature 176.
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28 (13), S. 2046 - 2057 (2018)
Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica. Current Biology 177.
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217 (7), S. 2329 - 2340 (2018)
Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 178.
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3 (12), e99941 (2018)
Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight 179.
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8, 8880 (2018)
Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Scientific Reports 180.
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15 (6), S. 463 - 466 (2018)
Integrative omics - from data to biology. Expert Review of Proteomics 181.
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Protein profiling of non-model plant Cuminum cyminum by gel-based proteomic approach. Phytochemical Analysis 182.
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Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis. The Journal of Biological Chemistry 183.
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22 (3), S. 1375 - 1384 (2018)
A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients. Clinical Oral Investigations 184.
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69 (6), S. 979 - 992 (2018)
Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 185.
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3 (3), S. 367 - 377 (2018)
The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiology 186.
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107 (5), S. 595 - 609 (2018)
sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. Molecular Microbiology 187.
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46 (3), S. 1470 - 1485 (2018)
Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa. Nucleic Acids Research 188.
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172 (3), S. 454 - 464, e1-e5 (2018)
Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 189.
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9 (419), eaam7816 (2017)
BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science Translational Medicine 190.
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31 (23-24), S. 2416 - 2429 (2017)
The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development 191.
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45 (20), S. 12025 - 12038 (2017)
Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex. Nucleic Acids Research 192.
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Mechanism of transcription anti-termination in human mitochondria. Cell 193.
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Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 194.
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Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. EMBO Reports 195.
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Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding. Scientific Reports 196.
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Combining cryo-electron microscopy (cryo-EM) and cross-linking mass spectrometry (CX-MS) for structural elucidation of large protein assemblies. Current Opinion in Structural Biology 197.
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45 (15), S. 8957 - 8967 (2017)
The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus. Nucleic Acids Research 198.
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Hypoxia-stimulated membrane trafficking requires T-plastin. Acta Physiologica 199.
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Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 200.
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A new role for FBP21 as regulator of Brr2 helicase activity. Nucleic Acids Research